Publications

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2022
Hamada, M. A., R. A. Hassan, A. M. Abdou, Y. M. Elsaba, A. S. Aloufi, H. Sonbol, and S. M. Korany, "Bio_Fabricated Levan Polymer from Bacillus subtilis MZ292983.1 with Antibacterial, Antibiofilm, and Burn Healing Properties", Applied Sciences, vol. 12,, pp. 6413, 2022.
Sonousi, A., R. A. Hassan, E. O. Osman, A. M. Abdou, and S. H. Emam, "Design and synthesis of novel quinazolinone-based derivatives as EGFR inhibitors with antitumor activity", Journal of enzyme inhibition and medicinal chemistry, vol. 37, issue 1, pp. 2644-2659, 2022.
Hassan, R. A., S. H. Emam, D. Hwang, G. - D. Kim, S. O. Hassanin, M. G. Khalil, A. M. Abdou, and A. Sonousi, Design, synthesis and evaluation of anticancer activity of new pyrazoline derivatives by down-regulation of VEGF: Molecular docking and apoptosis inducing activity, , 2022.
Hassan, R. A., Mohammed I.A. Hamed c, A. M. Abdou, and Y. El-Dash, "Novel antiproliferative agents bearing substituted thieno[2,3-d]pyrimidine scaffold as dual VEGFR-2 and BRAF kinases inhibitors and apoptosis inducers; design, synthesis and molecular docking", Bioorganic Chemistry, vol. 125, pp. 105861, 2022.
Halim, P. A., R. A. Hassan, K. O. Mohamed, S. O. Hassanin, M. G. Khalil, A. M. Abdou, and E. O. Osman, "Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 37, issue 1, pp. 189-201, 2022.
2021
Emam, S. H., A. Sonousi, E. O. Osman, D. Hwang, G. - D. Kim, and R. A. Hassan, "Design and synthesis of methoxyphenyl- and coumarin-based chalcone derivatives as anti-inflammatory agents by inhibition of NO production and down-regulation of NF-κB in LPS-induced RAW264.7 macrophage cells", Bioorganic Chemistry, vol. 107, pp. 104630, 2021.
El-Malah, A., Z. Mahmoud, H. HamedSalem, A. M. Abdou, M. M. H. Soliman, and R. A. Hassan, "Design, ecofriendly synthesis, anticancer and antimicrobial screening of innovative Biginelli dihydropyrimidines using β-aroylpyruvates as synthons", Green Chemistry Letters and Reviews, vol. 14, issue 2, pp. 220-232, 2021. design_ecofriendly_synthesis_anticancer_and_antimicrobial_screening_of_innovative_biginelli_dihydropyrimidines_using_aroylpyruvates_as_synthons.pdf
KASSAB, A. S. M. A. A. E., E. M. Gedawy, M. I. A. Hamed, A. S. Doghish, and R. A. Hassan, "Design, synthesis, anticancer evaluation, and molecular modelling studies of novel tolmetin derivatives as potential VEGFR-2 inhibitors and apoptosis inducers", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 36, issue 1, pp. 922-939, 2021.
El-Dash, Y., E. Elzayat, A. M. Abdou, and R. A. Hassan, Novel thienopyrimidine-aminothiazole hybrids: Design, synthesis, antimicrobial screening, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and VEGFR-2 inhibition, , 2021.
2020
Bakr, R. O., S. S. Zaghloul, R. A. Hassan, A. Sonousi, R. Wasfi, and M. A. A. Fayed, "Antimicrobial activity of Vitex agnus-castus Essential Oil and Molecular Docking Study of Its Major Constituents", Journal of Essential Oil Bearing Plants, vol. 23, issue 1, pp. 184-193, 2020.
2018
KASSAB, A. S. M. A. A. E., and R. A. Hassan, "Novel benzotriazole N-acylarylhydrazone hybrids: Design, synthesis, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and FAK inhibition", Bioorganic Chemistry, vol. 80, pp. 531-544, 2018. benzotriazole_anticancer_1.pdf
2015
Abdou, A. M., S. Botros, R. A. Hassan, D. F. Taber, A. T. Taher, and M. M. Kamel, "Useful four-carbon synthons en route to monastrol analogs", Tetrahedron, vol. 71, pp. 139-141, 2015. 1-s2.0-s0040402014015804-main.pdf
2014
Hassan, R. A., S. Botros, A. T. Taher, and M. M. Kamel, "Progress toward the synthesis of Brasilicardin A", 5th International Scientific Conference of Faculty of Pharmacy, Cairo University, Cairo university, April 23, 24, 2014.
2013
Taber, D. F., R. A. Hassan, and P. W. DeMatteo, "Simplified Preparation of Dimethyldioxirane (DMDO)", Organic Syntheses, vol. 90, pp. 350-357, 2013. dmdo.pdf
2006
Mahmoud, R. A., S. Botros, A. K. El-Ansary, and M. M. Kamel, "Synthesis of certain substituted Pyridazines and pyrimido[4,5-c]pyridazines of anticipated antimicrobial activity", Bulletin of Faculty of Pharmacy, Cairo University, vol. 43, issue 3, pp. 35-41, 2006. my_master_paper.pdf
2004
Mahmoud, R. A., S. Botros, A. K. El-Ansary, and M. M. Kamel, "Synthesis of Fused Pyridazine Heterocycles of Pharmaceutical Interest", 9th IBN SINA INTERNATIONAL CONFERENCE ON PURE AND APPLIED HETEROCYCLIC CHEMISTRY, Sharm Elshiek, December 11-14, , 2004.