Publications

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2023
El-Nassan, H. B., M. M. Farag, H. A. Merey, B. M. Eltanany, M. M. Galal, L. A. Rashed, and A. N. ElMeshad, "Comparative pharmacodynamic study delineating the efficacy of amantadine loaded nano-emulsified organogel via intranasal versus transdermal route in rotenone-induced Parkinson’s disease rat model", Journal of Drug Delivery Science and Technology , vol. 86, pp. 104765, 2023.
El-Nassan, H. B., Y. S. El-Dash, A. M. Mahmoud, and S. S. El-Mosallamy, "Electrochemical Synthesis of 5-Benzylidenebarbiturate Derivatives and Their Application as Colorimetric Cyanide Probe", Chemelectrochem, vol. 10, pp. e202200954, 2023.
El-Nassan, H. B., and M. A. Al-Qadhi, "Recent advances in the discovery of tropomyosin receptor kinases TRKs inhibitors: A mini review", European Journal of Medicinal Chemistry , vol. 258, pp. 115618, 2023.
El-Nassan, H. B., A. M. Mahmoud, and S. S. El-Mosallamy, "Unexpected formation of hexahydroxanthenediones by electrochemical synthesis in deep eutectic solvents", Sustainable Chemistry and Pharmacy, vol. 35, pp. 101207, 2023.
2022
Abdelhaleem, E. F., A. S. M. A. A. E. KASSAB, H. B. El-Nassan, and O. M. Khalil, "Design and Synthesis of Novel Celecoxib Analogues with Potential Cytotoxic and Pro-apoptotic Activity against Breast Cancer Cell Line MCF-7", Medicinal Chemistry, vol. 18, pp. 903-914, 2022. d0008c.pdf
Halim, P. A., H. B. El-Nassan, and Y. S. El-Dash, "Design and Synthesis of Novel Ibuprofen Derivatives as Selective COX-2 Inhibitors and Potential Anti-Inflammatory Agents: Evaluation of PGE2, TNF-α, IL-6 and Histopathological Study", Medicinal Chemistry, vol. 18, pp. 427-443, 2022.
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Abbas, H., Y. A. El-Feky, M. M. Al-Sawahli, N. M. EL-Deeb, H. B. El-Nassan, and M. Zewail, "Development and optimization of curcumin analog nano-bilosomes using 21.31 full factorial design for anti-tumor profiles improvement in human hepatocellular carcinoma: in-vitro evaluation, in-vivo safety assay", Drug Delivery, vol. 29, issue 1, pp. 714-727, 2022.
2021
El-Nassan, H., "Amberlyst 15®: An Efficient Green Catalyst for the Synthesis of Heterocyclic Compounds", Russian Journal of Organic Chemistry, vol. 57, issue 7, pp. 1109-1134, 2021. el-nassan2021_article_amberlyst15anefficientgreencat.pdf
Kamel, M. M., M. K. Abdel-hameid, H. B. El-Nassan, and E. A. E. - Khouly, "Synthesis and Cytotoxic Activity of Novel Mono- and Bis-Indole Derivatives: Analogues of Marine Alkaloid Nortopsentin", Medicinal Chemistry, vol. 17, issue 7, pp. 779 - 789, 2021.
2020
El‑Meligie, S., N. Khalil, H. B. El-Nassan, and A. Ibraheem, "Efcient synthesis of new 3‑amino‑4‑cyanothiophene derivatives", Chemical Papers, vol. 74, pp. 2491-2500, 2020.
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El‑Meligie, S., N. Khalil, H. B. El-Nassan, and A. Ibraheem, "New synthetic approaches to thieno[3,2‑d]pyrimidine and thieno[3,4‑b]pyridine derivatives", Chemical Papers, vol. 74, pp. 2501-2514, 2020.
application/pdf iconel-meligie2020_article_newsyntheticapproachestothieno.pdf
2019
El-Meligie, S. E. M., N. A. Khalil, H. B. El-Nassan, and A. A. M. Ibraheem, "A Review on the Synthetic Routes to β-Keto Amides", Current Organic Chemistry, vol. 23, issue 19, pp. 2005-2015, 2019.
Kamel, M. M., M. K. Abdel-hameid, H. B. El-Nassan, and E. A. E. - Khouly, "Synthesis and Cytotoxicity Evaluation of Novel Indole Derivatives as Potential Anti-Cancer Agents", medicinal chemistry, vol. 15, issue 8, pp. 873-882, 2019.
2018
El-Nassan, H. B., B. H. Naguib, and E. A. Beshay, "Synthesis of new pyridothienopyrimidinone and pyridothienotriazolopyrimidine derivatives as pim-1 inhibitors", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 33, issue 1, pp. 58-66, 2018. synthesis_of_new_pyridothienopyrimidinone_and_pyridothienotriazolopyrimidine_derivatives_as_pim_1_inhibitors.pdf
2017
Naguib, B. H., H. B. El-Nassan, and T. M. Abdelghany, "Synthesis of new pyridothienopyrimidinone derivatives as Pim-1 inhibitors", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 32, issue 1, pp. 457-467, 2017. synthesis_of_new_pyridothienopyrimidinone_derivatives_as_pim_1_inhibitors.pdf
2016
Naguib, B., and H. El-Nassan, "Synthesis of New Thieno[2,3-b]pyridine Derivatives as Pim-1 Inhibitors.", J enzyme inhibition and medicinal chemistry, vol. 31, issue 6, pp. 1718-1725, 2016. synthesis_of_new_thieno_2_3_b_pyridine_derivatives_as_pim_1_inhibitors.pdf
Zaher, A., S. Abuel-Maaty, H. El-Nassan, and S. Amer, "Synthesis, Antitumor Screening and cell cycle analysis of Novel Benzothieno[3,2-b]pyran Derivatives", J enzyme inhibition and medicinal chemistry, vol. 31, issue S4, pp. 145-153, 2016. synthesis_antitumor_screening_and_cell_cycle_analysis_of_novel_benzothieno_3_2_b_pyran_derivatives.pdf
2015
undefined, "Synthesis and antitumor activity of tetrahydrocarbazole hybridized with dithioate derivatives", J Enzyme Inhib Med Chem, vol. 30, issue 2, pp. 308-315, 2015. 147563662e20142e922554.pdf
2014
El-Nassan, H. B., "Recent progress in the identification of BRAF inhibitors as anti-cancer agents", Eur. J. Med. Chem., vol. 72, pp. 170-205, 2014. fkgfahvf.pdf
El-Nassan, H. B., "Synthesis and Structure Activity Relationship Study of N-substituted 3,5-diarylidenepiperidin-4-ones as potential antitumor agents", Anti-Cancer Agents Med. Chem., vol. 14, issue 2, pp. 319-330, 2014. modified_el-nassan-ms.3rd_proof.pdf
2013
El-Nassan, H. B., Advances in the discovery of kinesin spindle protein (Eg5) inhibitors as antitumor agents, : Eur. J. Med. Chem. 62, 614-631 , 2013.
Khalil, N. A., E. M. Ahmed, and H. B. El-Nassan, Synthesis, Characterization and Biological Evaluation of Certain 1,3-Thiazolone Derivatives Bearing Pyrazoline Moiety as Potential Anti-breast Cancer Agents, : Med. Chem. Res. 22,1021-1027, 2013.
2012
Khalil, N. A., E. M. Ahmed, H. B. El-Nassan, and A. A. - A. M. Osama K. Ahmed, Synthesis and Biological Evaluation of Novel Pyrazoline Derivatives as Anti-inflammatory and Antioxidant Agents, : Arch. Pharm. Res. 35, 995-1002 (2012), 2012.
Hameid, M. A. E. K., M. D. Mihovilovic, and H. B. El-Nassan, Synthesis of Novel Pyrazolo[3,4-d]pyrimidine Derivatives as Potential Anti-breast Cancer Agents, : Eur. J. Med. Chem. 57, 323-328 (2012), 2012.
2011
El-Enany, M. M., M. M. Kamel, O. M. Khalil, and H. B. El-Nassan, Synthesis and antitumor activity of novel pyrazolo[1,5-a]pyrimidine derivatives, : Eur. J. Chem. 2, 331-336 (2011), 2011.