Publications

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2023
Maged, A. M., A. El-Mazny, N. Kamal, S. I. Mahmoud, M. Fouad, N. El‑Nassery, amal Kotb, W. S. Ragab, A. I. Ogila, A. A. Metwally, et al., "Diagnostic accuracy of ultrasound in the diagnosis of Placenta accreta spectrum: systematic review and meta‑analysis", BMC pregnancy and childbirth, 2023.
Hassan, E. S., A. Maged, amal Kotb, M. Fouad, N. El-Nassery, and W. M. Kamal, "Effect of laser acupuncture on pain and density of bone in osteoporotic postmenopausal women: a randomized controlled trial", Menopause, vol. 30, issue 5, pp. 545-550, 2023.
Maged, A. M., A. El-Mazny, N. Kamal, S. I. Mahmoud, M. Fouad, N. El‑Nassery, amal Kotb, W. S. Ragab, A. I. Ogila, A. A. Metwally, et al., "The value of platelet‑rich plasma in women with previous implantation failure: a systematic review and meta‑analysis", Journal of Assisted Reproduction and Genetics, 2023.
Shehata, M. M. A., A. Maged, amal Kotb, A. I. Ogila, Y. Lasheen, N. Salah, R. A. Mohsen, M. Fouad, and A. S. Abd-elazeim, "Whole-body vibration versus supervised aerobic exercise on hormonal parameters and inflammatory status in women with premenstrual syndrome: A randomized controlled trial", International journal of Gynecology and Obstetrics, 2023.
2022
Meshaal, H., E. Salah, E. Fawzi, M. Abdel-Rasheed, A. Maged, and H. Saad, "Hysteroscopic management versus ultrasound‑guided evacuation for women with first‑trimester pregnancy loss, a randomised controlled trial", BMC women health, vol. 22, issue 190, 2022.
2020
Maged, A. M., M. Waly, R. M. Fahmy, A. S. Dieb, A. Essam, N. M. Salah, E. A. Hussein, and H. nabil, "Carbetocin versus rectal misoprostol for management of third stage of labor among women with low risk of postpartum hemorrhage", International journal of Gynecology and obstetrics, issue 148, pp. 238-242, 2020.
Maged, A. M., M. E. Hassanin, W. M. Kamal, A. H. Abbassy, M. Alalfy, A. H. M. E. D. N. ASKALANI, A. El-Lithy, M. Nabil, D. Farouk, E. A. Hussein, et al., "Effect of Low-Level Laser Therapy versus Electroacupuncture on Postnatal Scanty Milk Secretion: A Randomized Controlled Trial", American Journal of Perinatology, vol. 37, issue 12, pp. 1243-1249, 2020.
Maged, A. M., A. Elsherief, H. Hassan, D. S. Eldin, K. A. Omran, M. A. Mohamady, S. Dahab, R. Fahmy, A. A. HAK, A. Y. Shoab, et al., "Maternal, fetal, and neonatal outcomes among different types of hypertensive disorders associating pregnancy needing intensive care management", The Journal of Maternal-Fetal & Neonatal Medicine, vol. 33, issue 2, pp. 314-321, 2020.
Maged, A. M., H. nabil, A. S. Dieb, A. Essam, S. Ibrahim, W. Deeb, and R. M. Fahmy, "Prediction of metaphase II oocytes according to different levels of serum AMH in poor responders using the antagonist protocol during ICSI: a cohort study", Gynecological Endocrinology, vol. 36, issue 8, pp. 728-733, 2020.
2019
Maged, A. M., R. M. Fahmy, H. Rashwan, M. Mahmoud, S. Hassan, H. nabil, A. Hany, R. Lotfy, Y. Lasheen, S. Dahab, et al., "Effect of body mass index on the outcome of IVF cycles among patients with poor ovarian response", International journal of gynecology and obstetrics, vol. 144, pp. 161 -166, 2019.
Maged, A. M., A. M. Kamel, F. Abu-hamila, R. O. Elkomy, O. A. Ohida, S. M. Hassan, R. M. Fahmy, and W. Ramadan, "The measurement of endometrial volume and sub-endometrial vascularity to replace the traditional endometrial thickness as predictors of fertilization success.", Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, vol. 35, issue 11, pp. 949-954, 2019. Abstractthe_measurement_of_endometrial_volume_and_sub_endometrial_vascularity_to_replace_the_traditional_endometrial_thickness_as_predictors_of_in_vitro.pdf

To assess the value of endometrial thickness, volume, and sub-endometrial perfusion in women undergoing IVF. In 82 women candidate for ICSI, endometrial thickness and sub-endometrial perfusion were measured with a trans-vaginal 2 D ultrasound and 3 D power Doppler respectively on day of hCG trigger and Embryo transfer (ET). The primary outcome was the clinical pregnancy rate. Endometrial volume showing a statistically significant difference between pregnant and nonpregnant women (4.11 ± 1.19 vs. 3.4 ± 1.1  = .019) on day of triggering and at ET (4.02 ± 1.15 vs. 3.45 ± 0.90,  = .022). VFI was significantly higher in pregnant group at both days of triggering and ET (0.54 ± 0.48 vs. 0.33 ± 0.31 and 0.47 ± 0.22 vs. 0.34 ± 0.2,  = .02). At cutoff values of 3.265 and 2.95 cm3 (70 & 80% sensitivity, specificity 64.5 & 51.6%, a positive predictive value 38.9 & 34.8%, and negative predictive value 87.0 & 88.9%) to predict pregnancy on the day of hCG trigger & ET respectively. Cutoff value for Endometrial VFI on the day of ET was 0.674 (sensitivity of 70%, specificity of 80.6%, PPV 53.8%, and NPV 89.3%). Higher endometrial volume and VFI were associated with pregnancy.

Maged, A. M., T. Fawzi, M. A. Shalaby, A. Samy, M. A. Rabee, A. S. Ali, E. A. Hussein, B. Hammad, and W. S. Deeb, "A randomized controlled trial of the safety and efficacy of preoperative rectal misoprostol for prevention of intraoperative and postoperative blood loss at elective cesarean delivery", international journal of gynecology and obstetrics, vol. 147, issue 1, pp. 102-107, 2019. ijgo.12922.pdf
Maged, A. M., M. N. Mohesen, A. Elhalwagy, Hoda Abdelaal, M. A. Mohamady, A. A. Abdellatif, A. Alsawaf, K. A. Malek, H. nabil, R. M. Fahmy, et al., "Subcuticular interrupted versus continuous skin suturing in elective cesarean section in obese women: a randomized controlled trial", The Journal of Maternal-Fetal & Neonatal Medicine, vol. 32, issue 24, pp. 4114-4119, 2019.
2018
Maged, A. M., H. Rashwan, M. Mahmoud, A. El-Mazny, M. Farouk, Doaa S. Belal, and H. M. Marie, "Effect of Prolonged GnRH Agonist Downregulation on ICSI Outcome in Patients With Endometriomas of Less Than 5 cm: A Randomized Controlled Trial", Reproductive Sciences, vol. 25, issue 10, pp. 1509-1514, 2018. gnrh_in_eo_final.pdf
2016
Maged, A. M., H. Torky, M. A. Fouad, S. H. Gad Allah, N. M. Waked, A. S. Gayed, and A. K. Salem, "Role of antioxidants in gestational diabetes mellitus and relation to fetal outcome: a randomized controlled trial.", The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 29, issue 24, pp. 4049-54, 2016 Dec. Abstract

OBJECTIVE: To examine the effect of antioxidant administration on the oxidative parameters in both blood and placental tissue and its relation to fetal outcome in women with GDM.

PATIENTS AND METHODS: Two-hundred pregnant women with gestational diabetes mellitus (GDM) were randomized into 2 groups, Group1 received 1 gram L-ascorbic acid per day and Group2 received placebo.

RESULTS: The use of antioxidants significantly lower the needed insulin dose for blood sugar control (25.6 ± 20.3 versus 40.5 ± 23.7, respectively). In placental tissue homogenates, glutathione (GSH) was 49.6 ± 5.9 versus 62.34 ± 4.99, malondialdahyde (MDA) was 165.7 ± 9.2 versus 264.15 ± 12, superoxide dismutase (SOD) was 0.3 ± 0.3 versus 0.054 ± 0.16 while catalase (CAT) was 14.06 ± 2.4 versus 15.52 ± 3.97 and glutathione peroxidase (GPx) was 14 ± 4.1 versus 26.3 ± 4.26 in antioxidant group compared to the control group (p < 0.001). In maternal blood, GSH was 1.5 ± 0.3 versus 0.74 ± 0.088, CAT was 380.7 ± 11 versus 325.44 ± 21.8, GPx was 52.3 ± 8.7 versus 75.82 ± 6.84 and SOD was 188 ± 15.3 versus 98.56 ± 11.05 in antioxidant group compared to control group (p < 0.001). In neonatal blood, the level of MDA and SOD showed a statistically significant difference between antioxidants and control groups (4 ± 0.7 versus 6.6 7 ±0.66 and1 8 8 ± 15.3 versus 98.5 ± 11.05, respectively) (p < 0.001). The neonatal blood sugar after 1 and 2 hours of delivery was more stable in antioxidant group (56.7 ± 10.9 versus 39.7 ± 11.1 and 58.5 ± 10.8 versus 41.7 ± 13.1, respectively) (p <0.05). The neonates NICU admission was lower in antioxidant group (5 versus 11) (p <0.05).

CONCLUSION: The use of antioxidants markedly reverses the oxidative stresses in women with GDM with marked improvement on neonatal outcome.

Maged, A. M., M. Elsherbini, W. Ramadan, R. Elkomy, O. Hilal, D. Hatem, M. Fouad, and H. Gaafar, "Periconceptional risk factors of spina bifida among Egyptian population: a case–control study", Journal of maternal fetal and neonatal medicine, vol. 29, issue 14, pp. 2264–2267, 2016. 15_spina_bifida_final.pdf
Maged, A. M., H. Torky, M. A. Fouad, S. H. Gad Allah, N. M. Waked, A. S. Gayed, and A. K. Salem, "Role of antioxidants in gestational diabetes mellitus and relation to fetal outcome: a randomized controlled trial", The journal of maternal-fetal & neonatal medicine, vol. 29, issue 24, pp. 4049–4054, 2016. 7_antioxidants.pdf
Maged, A. M., A. A. Hafiz, W. A. I. Mostafa, N. El-Nassery, M. Fouad, E. Salah, and amal Kotb, "The role of prophylactic use of low dose aspirin and calheparin in patients with unexplained recurrent abortion", Gynecological Endocrinology, vol. 32, issue 12, pp. 970–972, 2016. 5the_role_of_prophylactic_use_of_low_dose_aspirin_and_calheparin_in_patients_with_unexplained_recurrent_abortion.pdf
2015
Maged, A. M., N. Elnassery, M. Fouad, A. A. Hafiz, and W. Al Mostafa, "Third-trimester uterine artery Doppler measurement and maternal postpartum outcome among patients with severe pre-eclampsia.", International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, vol. 131, issue 1, pp. 49-53, 2015 Oct. Abstract

OBJECTIVE: To evaluate the association between uterine artery Doppler measurements and maternal complications among women with severe pre-eclampsia.

METHODS: As part of a cross-sectional study, women with a single intrauterine pregnancy of more than 28 weeks and a diagnosis of severe pre-eclampsia were enrolled at a unit in Cairo, Egypt, between December 2012 and September 2014. Uterine artery Doppler was evaluated and maternal complications were recorded.

RESULTS: Among the 100 participants, 76 (76%) experienced maternal complications. There were significant differences in resistance index (RI) and pulsatility index (PI) between women who experienced no complications and those who had accidental hemorrhage, HELLP syndrome, and acute pulmonary edema (P<0.001 for all), and postpartum hemorrhage (P=0.004 and P<0.001, respectively). There was no significant difference in RI for women with postpartum fits (P=0.360). There was a statistically significant difference regarding RI (P<0.001) and PI (P=0.005) between cases presenting with complications and those without. There was a significant negative correlation between PI and gestational age (r=-0.988; P<0.001) and between RI and gestational age (r=-0. 854; P<0.001), but no significant correlation between PI or RI and age, systolic blood pressure, or diastolic blood pressure.

CONCLUSION: Increased uterine artery resistance in the third trimester of pregnancy could be used to predict postpartum maternal complications.

Maged, A. M., M. Elsherbini, W. Ramadan, R. Elkomy, O. Helal, D. Hatem, M. Fouad, and H. Gaafar, "Periconceptional risk factors of spina bifida among Egyptian population: a case–control study", The Journal of Maternal-Fetal & Neonatal Medicine, 2015. spina_bifida.pdf
Maged, A. M., N. S. Elnassery, M. A. Fouad, A. Abdelhafez, and W. A. I. Mostafa, "Third Trimester Uterine Artery Doppler Measurement in Severe Pre eclampsia Patients and Maternal Postpartum Outcome", International journal of gynecology and obstetrics, vol. 131, issue (2015), pp. 49–53, 2015. doppler_in_pih_final.pdf
2014
Maged, A. M., G. A. Fattah, W. A. I. Mostafa, and D. Ahmed, "Comparative study between different biomarkers for early prediction of gestational diabetes mellitus", The journal of maternal-fetal & neonatal medicine, vol. 27, issue 11, pp. 1108–1112, 2014.
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