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2023
Monsef, W. A. E. S., A. A. Ragab, S. M. M. Shanab, G. I. Mahmoud, and E. A. Shalaby, "Biological activities of polysaccharides fraction from Arthrospira platensis and Nostoc muscorum cultivated under abiotic stress conditions", Egyptian Pharmaceutical Journal, vol. 22, issue (4), pp. 582-599, 2023. biological_activities_of_polysaccharides_fraction.7.pdf
Shalaby, E. A., S. M. M. Shanab, H. M. Rehab, and E. A. El-Ansary, "Biological Activities of Some Citrus Fruit Peels extracts.", Egyptian Journal of chemistry, vol. 66, pp. 51-61, 2023.
Shalaby, E. A., S. M. M. Shanab, H. M. Rehab, and E. A. El-Ansary, "Biological Activities of Some Citrus Fruit Peels extracts.", Egyptian Journal of chemistry , 2023. ejchem_volume_66_issue_7_pages_51-61.pdf
Abdel-Wareth, M. T. A., E. A. M. Ali, and M. A. El-Shazly, "Biological Activity and GC-MS/MS Analysis of Extracts of Endophytic Fungi Isolated from Eichhornia crassipes (Mart.) Solms", Journal of Applied Biotechnology Reports, vol. 10, issue 1, pp. 895 - 909, 2023.
Omar, S., A. Fahmi, M. Abdur-Rahman, and M. Ghareeb, "Biological and Chemical Evaluation of Secondary Metabolites from Endophytic Fungi Isolated from Egyptian Ornamental Plants", Egyptian Journal of Chemistry, vol. 68, issue 8, pp. 267-282 , 2023.
Abdel-Hamid, M. A. M., M. A. Khalil, M. S. Abbas, A. S. Soliman, and others, "Biological control and molecular differences among some isolates of Alternaria solani, the causative agent of early blight in potatoes", Egyptian Journal of Chemistry, vol. 66, no. 9: National Information and Documentation Centre (NIDOC), Academy of Scientific …, pp. 421–438, 2023. Abstract
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and Mohamed A. M. Abdel-Hamid, M. A. Khalil, M. A. A. - E. - M. - M. A. S. S. S. L., "Biological control and molecular differences among some isolates of Alternaria solani, the causative agent of early blight in potatoes", Egyptian Journal of Chemistry, vol. 66, issue 9, pp. 421 - 438, 2023.
Farouk, A. T., O. E. Hassanein, O. I. Fahmy, A. M. Elkady, and H. E. L. Nahass, "Biological evaluation of indirect restorations in endodontically treated posterior teeth with deeply located proximal margins following deep margin elevation versus surgical crown lengthening: a randomized controlled trial.", Clinical oral investigations, vol. 28, issue 1, pp. 24, 2023. Abstract

OBJECTIVE: The current clinical trial was conducted to evaluate the effect of proximal indirect restorations in endodontically treated posterior teeth with deeply located margins following deep margin elevation compared to surgical crown lengthening.

MATERIAL AND METHODS: Deep proximal cavities in endodontically treated posterior teeth were randomly assigned into two groups; deep margin elevation (DME) or crown lengthening (CL). The clinical attachment level (CAL), probing depth (PD), bleeding on probing (BOP), crestal bone level (CBL), and secondary caries were evaluated at the baseline, 1, 3, 6, 9, and 12 months.

RESULTS: A total of 20 proximal cavities were included in the study; there was no significant difference between the two groups regarding mean CAL values at the baseline and 1 month, while there was a significant difference between the two groups in all other periods. Regarding the PD, there was no statistical significance between the two groups except at 9 and 12 months, where CL showed higher mean PD values than DME. There was no statistically significant difference in BOP or CBL between the two groups.

CONCLUSIONS: DME and CL are considered clinically successful with favorable biologic responses.

CLINICAL RELEVANCE: The deep margin elevation approach could provide a more conservative solution when relocating deeply seated cervical margins in a more coronal position. DME reduced the number of visits and time needed for the restoration of endodontically treated teeth. Surgical crown lengthening remains a gold standard procedure in the re-establishment of the supracrestal tissue attachment, especially in cases where cervical margins are beyond the elevation capacity.

Farouk, A. T., O. E. Hassanein, O. I. Fahmy, A. M. Elkady, and H. E. L. Nahass, "Biological evaluation of indirect restorations in endodontically treated posterior teeth with deeply located proximal margins following deep margin elevation versus surgical crown lengthening: a randomized controlled trial.", Clinical oral investigations, vol. 28, issue 1, pp. 24, 2023. Abstract

OBJECTIVE: The current clinical trial was conducted to evaluate the effect of proximal indirect restorations in endodontically treated posterior teeth with deeply located margins following deep margin elevation compared to surgical crown lengthening.

MATERIAL AND METHODS: Deep proximal cavities in endodontically treated posterior teeth were randomly assigned into two groups; deep margin elevation (DME) or crown lengthening (CL). The clinical attachment level (CAL), probing depth (PD), bleeding on probing (BOP), crestal bone level (CBL), and secondary caries were evaluated at the baseline, 1, 3, 6, 9, and 12 months.

RESULTS: A total of 20 proximal cavities were included in the study; there was no significant difference between the two groups regarding mean CAL values at the baseline and 1 month, while there was a significant difference between the two groups in all other periods. Regarding the PD, there was no statistical significance between the two groups except at 9 and 12 months, where CL showed higher mean PD values than DME. There was no statistically significant difference in BOP or CBL between the two groups.

CONCLUSIONS: DME and CL are considered clinically successful with favorable biologic responses.

CLINICAL RELEVANCE: The deep margin elevation approach could provide a more conservative solution when relocating deeply seated cervical margins in a more coronal position. DME reduced the number of visits and time needed for the restoration of endodontically treated teeth. Surgical crown lengthening remains a gold standard procedure in the re-establishment of the supracrestal tissue attachment, especially in cases where cervical margins are beyond the elevation capacity.

Al-Warhi, T., A. A. Al-karmalawy, A. A. Elmaaty, M. A. Alshubramy, M. Abdel-Motaal, T. A. Majrashi, M. Asem, A. Nabil, W. M. Eldehna, and Marwa Sharaky, "Biological evaluation, docking studies, and ADME prediction of some pyrimidine and pyridine derivatives as potential EGFR and EGFR inhibitors.", Journal of enzyme inhibition and medicinal chemistry, vol. 38, issue 1, pp. 176-191, 2023. Abstract

Herein, a set of pyridine and pyrimidine derivatives were assessed for their impact on the cell cycle and apoptosis. Human breast cancer (MCF7), hepatocellular carcinoma (HEPG2), larynx cancer (HEP2), lung cancer (H460), colon cancers (HCT116 and Caco2), and hypopharyngeal cancer (FADU), and normal Vero cell lines were used. Compounds and displayed outstanding effects on the investigated cell lines and were further tested for their antioxidant activity in MCF7, H460, FADU, HEP2, HEPG2, HCT116, Caco2, and Vero cells by measuring superoxide dismutase (SOD), malondialdehyde content (MDA), reduced glutathione (GSH), and nitric oxide (NO) content. Besides, Annexin V-FITC apoptosis detection and cell cycle DNA index using the HEPG-2 cell line were established on both compounds as well. Furthermore, compounds and were assessed for their EGFR kinase (Wild and T790M) inhibitory activities, revealing eligible potential. Additionally, molecular docking, ADME, and SAR studies were carried out for the investigated candidates.

Abdelaziz, M. H., A. S. Mohamed, Tawfik A. Ahmed, and M. H. El-Dakdoky, "Biological impacts of the green synthesized silver nanoparticles on the pregnant albino rats and their fetuses", Birth Defects Research, vol. 115, issue 4, pp. 441-457, 2023.
Abdel-Maksoud, G., H. E. Nasr, and M. S. kassem, "Biopolymer applications for different treatments of the historical paper manuscripts and leather bindings: A Review", Egyptian Journal of Chemistry, vol. 66, issue 11, pp. 637-652., 2023.
Faried, M., A. Khalifa, M. Samer, Y. A. Attia, M. A. Moselhy, A. El-Hussein, R. S. Yousef, K. Abdelbary, and E. M. Abdelsalam, "Biostimulation of green microalgae Chlorella sorokiniana using nanoparticles of MgO, Ca10 (PO4) 6 (OH) 2, and ZnO for increasing biodiesel production", Scientific Reports, vol. 13, issue 1: Nature Publishing Group UK London, pp. 19730, 2023. Abstract
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Faried, M.;, A.; Khalifa, M.; Samer, Y. A.; Attia, M. A.; Moselhy, A.; El-Hussein, R. S.; Yousef, K. Abdelbary, and E. Abdelsalam, "Biostimulation of green microalgae Chlorella sorokiniana using nanoparticles of MgO, Ca10 (PO4) 6 (OH) 2, and ZnO for increasing biodiesel production. ", Scientific Reports, vol. 13, issue 1, pp. 19730, 2023.
Faried, M., A. Khalifa, M. Samer, Y. A. Attia, M. A. Moselhy, A. El-Hussein, R. S. Yousef, K. Abdelbary, and E. M. Abdelsalam, "Biostimulation of green microalgae Chlorella sorokiniana using nanoparticles of MgO, Ca10(PO4)6(OH)2, and ZnO for increasing biodiesel production", Scientifc Reports, vol. 13, issue 1, pp. 19730, 2023.
Faried, M., A. Khalifa, M. Samer, Y. A. Attia, M. A. Moselhy, A. El-Hussein, R. S. Yousef, K. Abdelbary, and E. M. Abdelsalam, "Biostimulation of green microalgae Chlorella sorokiniana using nanoparticles of MgO, Ca10(PO4)6(OH)2, and ZnO for increasing biodiesel production", Scientific Reports, vol. 13, pp. 19730, 2023. faried_et_al-2023-scientific_reports.pdf
Abd El-Ghany, M. N., S. A. Hamdi, S. M. Korany, R. M. Elbaz, and M. G. farahat, "Biosynthesis of Novel Tellurium Nanorods by Gayadomonas sp. TNPM15 Isolated fromMangrove Sediments and Assessment of Their Impact on Spore Germination and Ultrastructure of Phytopathogenic Fungi", Microorganisms, vol. 11, issue 3, pp. 558-566, 2023.
Abdel Maksoud, G., M. Abdel Nasser, S. Hassan, A. M. Eid, A. Abdelnasser, and A. Fouda, "Biosynthesis of titanium dioxide nanoparticles using probiotic bacterial strain, Lactobacillus rhamnosus, and evaluate of their biocompatibility and antifungal activity", Biomass Conversion and Biorefnery, pp. 1-23., 2023.
Taha, S. K., E. A. Hassan, S. Mousa, G. T. El-Bassyouni, H. N. Shalash, and M. A. Abd El Hamid, "Biphasic calcium phosphate doped with zirconia nanoparticles for reconstruction of induced mandibular defects in dogs: cone-beam computed tomographic and histopathologic evaluation.", Journal of materials science. Materials in medicine, vol. 34, issue 6, pp. 27, 2023. Abstract

The present study aimed to evaluate osteogenic potential and biocompatibility of combining biphasic calcium phosphate with zirconia nanoparticles (4Zr TCP/HA) compared to biphasic calcium phosphate (TCP/HA) for reconstruction of induced mandibular defects in dog model. TCP/HA and 4Zr TCP/HA scaffolds were prepared. Morphological, physicochemical, antibacterial, cytocompatibility characterization were tested. In vivo application was performed in 12 dogs where three critical-sized mandibular defects were created in each dog. Bone defects were randomly allocated into: control, TCP/HA, and 4Zr TCP/HA groups. Bone density and bone area percentage were evaluated at 12 weeks using cone-beam computed tomographic, histopathologic, histomorphometric examination. Bone area density was statistically increased (p < 0.001) in TCP/HA and 4Zr TCP/HA groups compared to control group both in sagittal and coronal views. Comparing TCP/HA and 4Zr TCP/HA groups, the increase in bone area density was statistically significant in coronal view (p = 0.002) and sagittal view (p = 0.05). Histopathologic sections of TCP/HA group demonstrated incomplete filling of the defect with osteoid tissue. Doping with zirconia (4Zr TCP/HA group), resulted in statistically significant increase (p < 0.001) in bone formation (as indicated by bone area percentage) and maturation (as confirmed by Masson trichrome staining) compared to TCP/HA group. The newly formed bone was mature and organized with more trabecular thickness and less trabecular space in between. Physicochemical, morphological and bactericidal properties of combining zirconia and TCP/HA were improved. Combining zirconia and TCP/HA resulted in synergistic action with effective osteoinduction, osteoconduction and osteointegration suggesting its suitability to restore damaged bone in clinical practice.

Abdelhamid, I. A., M. R. Shaaban, and A. H. M. Elwahy, "Bis-aldehydes: Versatile precursors for bis-heterocycles", Advances in Heterocyclic Chemistry, vol. 139: Elsevier, pp. 135, 2023. Abstract
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Abdelhamid, I. A., M. R. Shaaban, and A. H. M. Elwahy, "Bis-aldehydes: Versatile precursors for bis-heterocycles", Advances in Heterocyclic Chemistry, vol. 139: Elsevier, pp. 135, 2023. Abstract
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Abdelhamid, I. A., M. R. Shaaban, and A. H. M. Elwahy, "Bis-aldehydes: Versatile precursors for bis-heterocycles", Advances in Heterocyclic Chemistry, vol. 139: Academic Press, pp. 135–200, 2023. Abstract
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Mekawy Ouda, A. M., "Block of ’the Royal Scribe’ Siesi at the Egyptian Museum Cairo (TR. 19.5.25.3)", Chronique d’Egypte , vol. XCVIII, 2023.
Chavda, V. P., N. Raval, S. Sheta, L. K. Vora, F. Elrashdy, E. M. Redwan, V. N. Uversky, and Y. N. Ertas, "Blood filtering system for COVID-19 management: novel modality of the cytokine storm therapeutics", Frontiers in Immunology, vol. 14, 2023.
Mahmoud, N., M. A. Mohamed, R. M. Hafez, and T. A. A. Moussa, "Bloodstream infection with Candida auris in Egypt", bioscience research, vol. 20, issue 4, pp. 1-13, 2023. blood_stream.pdf
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