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2022
Madnay, M. M. Y., W. A. Obaid, S. Selim, A. M. Reyad, E. A. Alsherif, S. M. Korany, M. Abdel-Mawgoud, and H. AbdElgawad, "Rhodospirillum sp. JY3: An innovative tool to mitigate the phytotoxic impact of galaxolide on wheat (Triticum aestivum) and faba bean (Vicia faba) plants", Frontiers in Plant Science, vol. 13: Frontiers Media SA, pp. 1037474, 2022. Abstract
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El-Hawarya, S. S., H. M. EL-Hefnawya, M. N. Elemeeryb, S. M. Osman, M. A. El-Raey, F. A. Mokhtar, Cheol H. Pand, and H. A. Ibrahimi, "The role of active metabolites isolated from Jasminum multiflorum flowers against hepatitis C virus infection and related hepatocellular carcinoma", Natural Product Research, vol. 36, issue 10, pp. 2625-2629, 2022.
Abdelghafar, E. M., A. H. Othman, M. M. Elrawas, A. M. KILANY, and E. H. Shaker, "The role of duloxetine in reducing opioid consumption after thoracotomy: a prospective, randomized, double-blinded, placebo-controlled pilot trial", Minerva Anestesiologica, vol. 88, issue 10, pp. 780-788, 2022.
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El-Saadony, M. T., A. M. Saad, S. M. Soliman, H. M. Salem, A. E. M. Desoky, O. Babalghith, A. M. Eltahan, O. M. Ibrahim, A. A. Ebrahim, T. A. Abd El Mageed, et al., "Role of nanomaterials in enhancing crop tolerance to abiotic stress: a comprehensive review.", . Frontiers in Plant Science, , vol. 2448., 2022. role_of_nanomaterials_in_enhancing_crop_tolerance_to_abiotic_stress.pdf
Seleim, S. M., M. S. Mostafa, N. H. Ouda, and R. Y. shash, "The role of pmrCAB genes in colistin‑resistant Acinetobacter baumannii", Scientific Reports, vol. 12, 2022.
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Albadawy, R., A. H. Hasanin, S. H. A. Agwa, S. Hamady, Y. M. Aboul-Ela, M. H. Raafat, S. S. Kamar, M. Othman, Y. A. Yahia, and M. Matboli, "Rosavin Ameliorates Hepatic Inflammation and Fibrosis in the NASH Rat Model via Targeting Hepatic Cell Death.", International journal of molecular sciences, vol. 23, issue 17, 2022. Abstract

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver disease that urgently needs effective therapy. Rosavin, a major constituent of the Rhodiola Rosea plant of the family Crassulaceae, is believed to exhibit multiple pharmacological effects on diverse diseases. However, its effect on non-alcoholic steatohepatitis (NASH), the progressive form of NAFLD, and the underlying mechanisms are not fully illustrated.

AIM: Investigate the pharmacological activity and potential mechanism of rosavin treatment on NASH management via targeting hepatic cell death-related () mRNAs and their upstream noncoding RNA regulators ( and ) in NASH rats.

RESULTS: High sucrose high fat (HSHF) diet-induced NASH rats were treated with different concentrations of rosavin (10, 20, and 30 mg/kg/day) for the last four weeks of dietary manipulation. The data revealed that rosavin had the ability to modulate the expression of the hepatic cell death-related RNA panel through the upregulation of both () mRNAs and their epigenetic regulators ( and ). Moreover, rosavin ameliorated the deterioration in both liver functions and lipid profile, and thereby improved the hepatic inflammation, fibrosis, and apoptosis, as evidenced by the decreased protein levels of IL6, TNF-α, and caspase-3 in liver sections of treated animals compared to the untreated NASH rats.

CONCLUSION: Rosavin has demonstrated a potential ability to attenuate disease progression and inhibit hepatic cell death in the NASH animal model. The produced effect was correlated with upregulation of the hepatic cell death-related (, , , and ) mRNAs-(-() RNA panel.

Agrawal, P., T. Ganesh, D. Oliva, and A. W. Mohamed, "S-shaped and v-shaped gaining-sharing knowledge-based algorithm for feature selection", Applied Intelligence, vol. 52, issue 1: Springer US New York, pp. 81-112, 2022. Abstract
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D, J., T. H.S, H. W, B. U, E. N. M., A. K, S. O, Y. A, D. A.A, E. - S. H.E, et al., "SARS-CoV-2 genome variations and evolution patterns in Egypt: a multi-center study", Scientific Reports, vol. 12, issue 1, pp. 14511, 2022.
Othman, E. M., A. A. Elgrahi, M. H. Ahmad, and R. O. K. A. I. A. A. TOSON, "Scar prevention by low level laser therapy on surgical wound post hand flexor tendon repair", Fizjoterapia Polska,, 2022.
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Hegab, A. A., H. M. Omar, M. Abuoward, S. G. Ghattas, N. E. Mahmoud, and M. M. Fahmy, "Screening and phylogenetic characterization of tick-borne pathogens in a population of dogs and associated ticks in Egyp", Parasites & Vectors, vol. 15, issue Open Access, pp. 222, 2022.
Hegab, Omar, H., Abuowarda, M.M., Ghattas, S.G., N. E. Mahmoud, and Fahmy, "Screening and phylogenetic characterization of tick-borne pathogens in a population of dogs and associated ticks in Egypt. ", Parasites & Vectors,, vol. 15, issue 1, pp. 222, 2022.
Collaboration, C. M. S., and others, "Search for a W'boson decaying to a vector-like quark and a top or bottom quark in the all-jets final state at $$\backslash$sqrt $\{$s$\}$ $= 13 TeV", arXiv preprint arXiv:2202.12988, 2022. Abstract
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Sirunyan, A. M., A. Tumasyan, W. Adam, F. Ambrogi, T. Bergauer, J. Brandstetter, M. Dragicevic, J. Ero, A. Escalante Del Valle, M. Flechl, et al., "Search for heavy Higgs bosons decaying to a top quark pair in proton-proton collisions at root s= 13 TeV (vol 04, 171, 2020)", JOURNAL OF HIGH ENERGY PHYSICS, no. 3: SPRINGER, 2022. Abstract
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Tumasyan, A., W. Adam, J. W. Andrejkovic, T. Bergauer, S. Chatterjee, M. Dragicevic, E. A. Del Valle, R. Frühwirth, M. Jeitler, N. Krammer, et al., "Search for heavy resonances decaying to W W, W Z, or W H boson pairs in a final state consisting of a lepton and a large-radius jet in proton-proton collisions at s= 13 TeV", Physical Review D, vol. 105, no. 3: APS, pp. 032008, 2022. Abstract
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Tumasyan, A., W. Adam, J. W. Andrejkovic, T. Bergauer, S. Chatterjee, M. Dragicevic, E. A. Del Valle, R. Frühwirth, M. Jeitler, N. Krammer, et al., "Search for heavy resonances decaying to Z ($ν$ $ν${\={}}) V (q q{\={}}′) in proton-proton collisions at s= 13 TeV", Physical Review D, vol. 106, no. 1: APS, pp. 012004, 2022. Abstract
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Benecke, A., A. Bethani, G. Bruno, F. Bury, C. Caputo, P. David, C. Delaere, I. S. Donertas, A. Giammanco, K. Jaffel, et al., "Search for long-lived particles decaying into muon pairs in proton-proton collisions at $$\backslash$sqrt $\{$s$\}$ $= 13 TeV collected with a dedicated high-rate data stream", Journal of High Energy Physics, vol. 4, 2022. Abstract
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Tumasyan, A., W. Adam, J. W. Andrejkovic, T. Bergauer, S. Chatterjee, M. Dragicevic, A. Escalante Del Valle, R. Frühwirth, M. Jeitler, N. Krammer, et al., "Search for long-lived particles decaying into muon pairs in proton-proton collisions at s $$$\backslash$sqrt $\{$s$\}$ $$= 13 TeV collected with a dedicated high-rate data stream", Journal of High Energy Physics, vol. 2022, no. 4: Springer, pp. 1–45, 2022. Abstract
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Belforte, S., V. Candelise, M. Casarsa, A. Da Rold, G. Della Ricca, G. Sorrentino, F. Vazzoler, and others, Search for long-lived particles decaying into muon pairs in proton-proton collisions at sqrt (s)= 13 TeV collected with a dedicated high-rate data stream, , 2022. Abstract
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Blekman, F., E. S. Bols, J. D'Hondt, J. T. De Clercq, M. Delcourt, H. El Faham, S. Lowette, S. Moortgat, A. Morton, D. Müller, et al., "Search for long-lived particles decaying to leptons with large impact parameter in proton-proton collisions at $$\backslash$sqrt $\{$s$\}$ $= 13 TeV", European Physical Journal C-Particles & Fields, vol. 2022, no. 01: Springer Verlag, pp. 177, 2022. Abstract
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Tumasyan, A., W. Adam, J. W. Andrejkovic, T. Bergauer, S. Chatterjee, K. Damanakis, M. Dragicevic, A. Valle, R. Fruehwirth, M. Jeitler, et al., "Search for long-lived particles decaying to leptons with large impact parameter in proton–proton collisions at $$$\backslash$sqrt $\{$s$\}$= 13$\backslash$,$\backslash$text $\{$Te$\}$$\backslash$text $\{$V$\}$ $$", The European Physical Journal C, vol. 82, no. 2: Springer, pp. 1–32, 2022. Abstract
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ALPANA, K., A. Tumasyan, S. DUBE, A. RASTOGI, S. PANDEY, A. LAHA, S. Sharma, B. KANSAL, A. RANE, C. M. S. Collaboration, et al., Search for long-lived particles decaying to leptons with large impact parameter in proton–proton collisions at√ s= 13TeV, : Springer Nature, 2022. Abstract
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Benecke, A., A. Bethani, G. Bruno, F. Bury, C. Caputo, P. David, C. Delaere, I. S. Donertas, A. Giammanco, K. Jaffel, et al., "Search for long-lived particles produced in association with a Z boson in proton-proton collisions at $$\backslash$sqrt $\{$s$\}$ $= 13 TeV", Journal of High Energy Physics, vol. 3, 2022. Abstract
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Tumasyan, A., W. Adam, J. W. Andrejkovic, T. Bergauer, S. Chatterjee, M. Dragicevic, A. Escalante Del Valle, R. Fruehwirth, M. Jeitler, N. Krammer, et al., "Search for long-lived particles produced in association with a Z boson in proton-proton collisions at s $$$\backslash$sqrt $\{$s$\}$ $$= 13 TeV", Journal of High Energy Physics, vol. 2022, no. 3: Springer, pp. 1–37, 2022. Abstract
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Tumasyan, A., W. Adam, T. Bergauer, M. Dragicevic, J. Erö, A. Valle, R. Frühwirth, M. Jeitler, N. Krammer, L. Lechner, et al., Search for low-mass dilepton resonances in Higgs boson decays to four-lepton final states in proton–proton collisions at $$ sqrt $\{$s$\}$= 13, ext $\{$TeV$\}$ $$, , 2022. Abstract
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Tumasyan, A., W. Adam, T. Bergauer, M. Dragicevic, J. Erö, A. Valle, R. Frühwirth, M. Jeitler, N. Krammer, L. Lechner, et al., "Search for low-mass dilepton resonances in Higgs boson decays to four-lepton final states in proton–proton collisions at $$$\backslash$sqrt $\{$s$\}$= 13$\backslash$,$\backslash$text $\{$TeV$\}$ $$ s= 13 TeV", The European Physical Journal C, vol. 82, no. 4: Springer, pp. 1–28, 2022. Abstract
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