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2023
Ismael, H. F., T. A. Sulaiman, and M. S. Osman, "Multi-solutions with specific geometrical wave structures to a nonlinear evolution equation in the presence of the linear superposition principle", Communications in Theoretical Physics, vol. 75, pp. 015001, 2023.
Abdelatty, M. A., N. Aboelmagd, M. F. Osman, M. T. Mohamed, and S. Mohamed, "Multimodality imaging in assessment of intestinal complications pre-stomal reversal", Egyptian Journal of Radiology and Nuclear Medicine, vol. 51, issue 140, 2023.
Eissa, E. - S. H., W. K. Bazina, Y. M. Abd El-Aziz, N. A. Abd Elghany, W. A. Tawfik, M. I. Mossa, Ola Hasan Abd El Megeed, N. N. B. Abd El-Hamed, A. F. El-Saeed, E. El-Haroun, et al., "Nano-selenium impacts on growth performance, digestive enzymes, antioxidant, immune resistance and histopathological scores of Nile tilapia, Oreochromis niloticus against Aspergillus flavus infection", Aquaculture International, vol. 32, issue 2, pp. 1587 - 1611, 2023.
El-Shiekh, R. A., R. M. S. Ashour, M. O. N. A. M. OKBA, A. A. Mandour, O. Kutkat, Y. Moatasim, and R. Elshimy, "Natural compounds as possible anti-SARS-CoV-2 therapeutic agents: an and study.", Natural product research, pp. 1-6, 2023. Abstract

WHO declared severe acute respiratory syndrome coronavirus-2' (SARS-CoV-2) was global health emergency since 2020. In our study eighteen natural compounds were investigated for possible anti-SARS-CoV-2 potential, where the most potent natural compounds were ursolic acid and dioscin with IC value of 4.49 µg/mL and 7.11 µg/mL, respectively. Hesperidin, catechin, diosmin, isorhamnetin-3--glucoside and hyperoside showed medium antiviral activity with IC value of 20.87, 22.57, 38.92, 39.62 and 47.10 µg/mL, respectively. Molecular modelling studies including docking study and predictive ADME study were performed on all tested molecules. Their binding energies after docking were calculated and their orientations at the active sites of both SARS-CoV-2 main protease (Mpro) and spike (S) receptors were visualised and compared to the downloaded ligands. Also, the predictive ADME studies showed good pharmacokinetic properties of most of the tested compounds. The obtained results obtained confirmed that many of the tested compounds are promising SARS-CoV-2 inhibitors.

El-Shiekh, R. A., R. M. S. Ashour, M. O. N. A. M. OKBA, A. A. Mandour, O. Kutkat, Y. Moatasim, and R. Elshimy, "Natural compounds as possible anti–SARS-CoV-2 therapeutic agents: an in-vitro and in-silico study", Natural Product Research: Taylor & Francis, pp. 1–6, 2023. Abstract
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Narayan, V. S., E. Alagha, W. Ouwerkerk, S. E. Uitentuis, J. E. Lommerts, S. Esmat, R. M. Mogawer, N. Ragab, S. Y. Chuah, S. Thng, et al., "NB-UVB phototherapy response of different body regions in non-segmental vitiligo.", Journal of the European Academy of Dermatology and Venereology : JEADV, vol. 37, issue 6, pp. e782-e785, 2023.
El‑Hawary1, S. S., M. A. Albalawi2, A. O. S. Montasser3, 4 Shaimaa R. Ahmed1, Sumera Qasim5, A. A. Shati6, M. Y. Alfaifi6, S. E. I. Elbehairi6, Omnia F. Hassan7, 9 Abdelfattah A. Sadakah8, et al., "Network pharmacology and molecular docking study for biological pathway detection of cytotoxicity of the yellow jasmine flowers", BMC Complementary Medicine and Therapies, vol. 23, issue 164, pp. 1-16, 2023. 1-vetiver_aerial_parts_and_roots_ameliora...pdf
Omar, M. A., R. E. Hawary, A. Eldash, K. M. Sadek, N. A. Soliman, M. O. F. Hanna, and S. M. Shawky, "Neutrophilic Myeloid-Derived Suppressor Cells and Severity in SARS-CoV-2 Infection.", Laboratory medicine, 2023. Abstract

BACKGROUND: While we strive to live with SARS-CoV-2, defining the immune response that leads to recovery rather than severe disease remains highly important. COVID-19 has been associated with inflammation and a profoundly suppressed immune response.

OBJECTIVE: To study myeloid-derived suppressor cells (MDSCs), which are potent immunosuppressive cells, in SARS-CoV-2 infection.

RESULTS: Patients with severe and critical COVID-19 showed higher frequencies of neutrophilic (PMN)-MDSCs than patients with moderate illness and control individuals (P = .005). Severe disease in individuals older and younger than 60 years was associated with distinct PMN-MDSC frequencies, being predominantly higher in patients of 60 years of age and younger (P = .004). However, both age groups showed comparable inflammatory markers. In our analysis for the prediction of poor outcome during hospitalization, MDSCs were not associated with increased risk of death. Still, patients older than 60 years of age (odds ratio [OR] = 5.625; P = .02) with preexisting medical conditions (OR = 2.818; P = .003) showed more severe disease and worse outcome. Among the immunological parameters, increased C-reactive protein (OR = 1.015; P = .04) and lymphopenia (OR = 5.958; P = .04) strongly identified patients with poor prognosis.

CONCLUSION: PMN-MDSCs are associated with disease severity in COVID-19; however, MDSC levels do not predict increased risk of death during hospitalization.

Qureshi, S., M. A. Akanbi, A. A. Shaikh, A. S. Wusu, O. M. Ogunlaran, W. Mahmoud, and M. S. Osman, "A new adaptive nonlinear numerical method for singular and stiff differential problems", Alexandria Engineering Journal, vol. 74, pp. 585-597, 2023.
Khalil, N. A., E. M. Ahmed, A. S. H. R. A. F. F. ZAHER, S. M. Alhamaky, N. Osama, and M. S. El-Zoghbi, "New benzothienopyran and benzothienopyranopyrimidine derivatives as topoisomerase I inhibitors: Design, synthesis, anticancer screening, apoptosis induction and molecular modeling studies", Bioorganic Chemistry, vol. 137, pp. 106638, 2023.
Zedan, I. A., M. M. Soliman, K. M. Elsayed, and H. M. Onsi, "A New Matching Strategy for SIFT Based Copy-Move Forgery Detection", International Journal of Intelligent Engineering and Systems, vol. 16, issue 4, pp. 422-435, 2023.
Iqbal, A. M., D. Baleanu, M. M. Miah, H. M. S. Ali, H. M. Alshehri, and M. S. Osman, "New soliton solutions of the mZK equation and the Gerdjikov-Ivanov equation by employing the double (G'/G, 1/G) -expansion method", Results in Physics, vol. 47, pp. 106391, 2023.
Akbar, A. M., F. A. Abdullah, M. T. Islam, M. A. A. Sharif, and M. S. Osman, "New solutions of the soliton type of shallow water waves and superconductivity models", Results in Physics, vol. 44, pp. 106180, 2023.
Eissa, I. H., R. G. Yousef, H. Elkady, E. B. Elkaeed, D. Z. Husein, I. M. Ibrahim, B. A. Alsfouk, A. S. Doghish, H. A. El-Mahdy, A. M. Kenawy, et al., "New theobromine derivative as apoptotic anti-triple-negative breast cancer targeting EGFR protein: CADD story", Journal of Molecular Structure, vol. 1294: Elsevier, pp. 136336, 2023. Abstract
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Mahdy, H. A., H. Elkady, M. S. Taghour, A. Elwan, M. A. Dahab, M. A. Elkady, E. G. E. Elsakka, E. B. Elkaeed, B. A. Alsfouk, I. M. Ibrahim, et al., "New theobromine derivatives inhibiting VEGFR-2: design, synthesis, antiproliferative, docking and molecular dynamics simulations", Future Medicinal Chemistry, vol. 15, no. 14: Future Science, pp. 1233–1250, 2023. Abstract
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Elkady, H., A. A. Abuelkhir, M. Rashed, M. S. Taghour, M. A. Dahab, H. A. Mahdy, A. Elwan, H. A. Al-Ghulikah, E. B. Elkaeed, I. M. Ibrahim, et al., "New thiazolidine-2, 4-diones as effective anti-proliferative and anti-VEGFR-2 agents: Design, synthesis, in vitro, docking, MD simulations, DFT, ADMET, and toxicity studies", Computational Biology and Chemistry, vol. 107: Elsevier, pp. 107958, 2023. Abstract
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Elkady, H., A. A. Abuelkhir, M. Rashed, M. S. Taghour, M. A. Dahab, H. A. Mahdy, A. Elwan, H. A. Al-Ghulikah, E. B. Elkaeed, I. M. Ibrahim, et al., "New thiazolidine-2, 4-diones as effective anti-proliferative and anti-VEGFR-2 agents: Design, synthesis, in vitro, docking, MD simulations, DFT, ADMET, and toxicity studies", Computational Biology and Chemistry, vol. 107: Elsevier, pp. 107958, 2023. Abstract
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Gaber, A. A., M. Sobhy, A. Turky, W. M. Eldehna, S. A. El-Sebaey, S. A. El-Metwally, A. M. El-Naggar, I. M. Ibrahim, E. B. Elkaeed, A. M. Metwaly, et al., "New [1, 2, 4] triazolo [4, 3-c] quinazolines as intercalative Topo II inhibitors: Design, synthesis, biological evaluation, and in silico studies", Plos one, vol. 18, no. 1: Public Library of Science San Francisco, CA USA, pp. e0274081, 2023. Abstract
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Fadaly, W. A. A., M. T. M. Nemr, T. H. Zidan, F. E. A. Mohamed, M. M. Abdelhakeem, N. A. N. Jayab, H. A. Omar, and K. R. A. Abdellatif, "New1,2,3triazole/1,2,4triazole hybrids linked to oxime moiety as nitric oxide donor selective COX-2,aromatase,B-RAFV600E and EGFR inhibitors celecoxib analogs:design,synthesis,antiinflammatory/antiproliferative activities,apoptosis and molecular modeling", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 38, issue 1, pp. 2290461, 2023.
Ragaie, C., N. A. Kishk, A. Nawito, A. S. Othman, and R. Magdy, "Non-convulsive status epilepticus in Sotos syndrome: rare first presentation in a rare syndrome", International Journal of Neuroscience, vol. 133, issue 1, pp. 81 - 85, 2023.
Ragaiea, C., N. A. Kishk, A. M. Nawitob, A. S. Othmana, and R. Magdy, "Non-convulsive status epilepticus in Sotos syndrome: rare first presentation in a rare syndrome", International Journal of Neuroscience, vol. 133, issue 1, pp. 81-85, 2023.
Yao, S. - W., O. A. Arqub, S. Tayebi, M. S. Osman, W. Mahmoud, M. Inc, and H. Alsulami, "A NOVEL COLLECTIVE ALGORITHM USING CUBIC UNIFORM SPLINE AND FINITE DIFFERENCE APPROACHES TO SOLVING FRACTIONAL DIFFUSION SINGULAR WAVE MODEL THROUGH DAMPING-REACTION FORCES", Fractals, vol. 31, issue 4, 2023.
Shi, L., S. Tayebi, O. A. Arqub, M. S. Osman, P. Agarwal, W. Mahamoud, M. Abdel-Aty, and M. Alhodaly, "The novel cubic B-spline method for fractional Painlevé and Bagley-Trovik equations in the Caputo, Caputo-Fabrizio, and conformable fractional sense", Alexandria Engineering Journal, vol. 65, pp. 413-426, 2023.
Shi, L., S. Tayebi, O. A. Arqub, M. S. Osman, P. Agarwal, W. Mahamoud, M. Abdel-Aty, and M. Alhodaly, "The novel cubic B-spline method for fractional Painleve´ and Bagley-Trovik equations in the Caputo, Caputo-Fabrizio, and conformable fractional sense", Alexandria Engineering Journal, vol. 65, pp. 413-426, 2023.
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