Mohamed, A. A., L. Rashed, H. Amin, M. Abu-Farha, S. A. El Fadl, and S. Pakhoum,
"K469E polymorphism of the intercellular adhesion molecule-1 gene in Egyptians with coronary heart disease.",
Annals of Saudi medicine, vol. 30, issue 6, pp. 432-6, 2010 Nov-Dec.
AbstractBACKGROUND AND OBJECTIVES: The initial step in atherosclerosis is the adhesion of leukocytes to activated endothelial cells mediated by intercellular adhesion molecule-1 (ICAM-1). This study aimed to investigate the association of K469E polymorphism of the ICAM-1 gene and soluble ICAM-1 (sICAM-1) serum level with coronary heart disease (CHD) in Egyptian subjects.
PATIENTS AND METHODS: Using a case-control design, we studied 100 patients with CHD, including 73 patients with acute myocardial infarction (MI) and 27 with unstable angina (UA). The control group consisted of 50 healthy subjects with normal left ventricular function. All participants were genotyped for the ICAM-1 polymorphism by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Serum sICAM-1 was measured by enzyme-linked immunoassay (ELISA).
RESULTS: In CHD patients, the frequencies of K genotype (KK and EK) were significantly higher when compared to controls (P<.001) and were associated with an increased risk of disease development (OR=3.8, 95% CI: 1.7 to 8.5; P=.001). K genotype frequencies in patients with MI showed no significant difference when compared to patients with UA (P= .121). Serum sICAM-1 levels were comparable between CHD patients and controls (P= .37) and between MI and UA patients (P=.23). There were no significant differences in sICAM-1 levels among patients with different genotypes (P=.532). Men presented with higher sICAM-1 levels than women (P=.004).
CONCLUSION: ICAM-1 gene polymorphism in codon 469 is associated with a risk for CHD development in Egyptian subjects. Serum sICAM-1 is not influenced by this polymorphism and is not necessarily elevated in CHD.
Folco, L., M. D. Martino, A. E. Barkooky, M. D'Orazio, A. Lethy, S. Urbini, I. Nicolosi, M. Hafez, C. Cordier, M. van Ginneken, et al.,
"The Kamil Crater in Egypt",
SCIENCE, vol. 329, pp. 804, 2010.
A.Ewais, H., M. R. Shehata, M. A. Nagdy, and A. A. Abdel-Khalek,
"Kinetics and mechanism of oxidation of the ternary complex of cobalt(II) involving N-(2-acetamido) iminodiacetic acid and malonate by periodate in acetate medium.",
Inorganic Chemistry An Indian Journal (ICAIJ), vol. 5, issue 2, pp. 83-88, 2010.
Shoukry, A. A., M. M. Shoukry, and M. N. Hafez,
"Kinetics of base hydrolysis of -amino acid esters catalyzed by palladium(II) piperazine complex ",
Central European Journal of Chemistry , , vol. 8, issue 4, pp. 797-805, 2010.
Hamza, H. S., J. Martinez, and J. L. Mugartza,
"KOPLE: knowledge-oriented product line engineering",
Proceedings of the ACM international conference companion on Object oriented programming systems languages and applications companion: ACM, pp. 275–276, 2010.
AbstractThe maturity of Knowledge Engineering (KE) theory and practice presents a real opportunity for advancing the state-of-the-art and state-of-the-practice in software Product-line Engineering (PLE). Several challenges that face the adoption and implementation of PLE in practice can be addressed by exploiting advanced technique from KE. This paper introduces the concept of KOPLE and describes the related one-day workshop that will be held in conjunction with SPLASH 2010.
Essam, T., M. A. Amin, O. E. L. Tayeb, B. Mattiasson, and B. Guieysse,
"Kinetics and metabolic versatility of highly tolerant phenol degrading Alcaligenes strain TW1",
Journal of Hazardous Materials, vol. 173, no. 1-3: Elsevier, pp. 783–788, 2010.
Abstractn/a
Essam, T., M. A. Amin, O. E. L. Tayeb, B. Mattiasson, and B. Guieysse,
"Kinetics and metabolic versatility of highly tolerant phenol degrading Alcaligenes strain TW1",
Journal of Hazardous Materials, vol. 173, no. 1-3: Elsevier, pp. 783–788, 2010.
Abstractn/a