Ezzat, M. A. F., S. M. Abdelhamid, M. A. Fouad, H. A. Abdel‐Aziz, and H. A. Allam, "Design, synthesis, in vitro, and in vivo evaluation of novel phthalazinone‐based derivatives as promising acetylcholinesterase inhibitors for treatment of Alzheimer's disease", Drug Development Research, vol. 84, issue 6, pp. 1231–1246, 2023.
application/pdf iconphthalazinone_paper.pdf
Ezzat, M. A. F., G. F. Elmasry, M. A. M. A. El‐Mageed, M. A. Fouad, H. A. Abdel‐Aziz, and S. I. Elewa, "Design, synthesis, and biological evaluation of furan‐bearing pyrazolo[3,4‐b]pyridines as novel inhibitors of CDK2 and P53–MDM2protein–protein interaction", Drug Development Research, vol. 84, issue 6, pp. 1183–1203, 2023.
application/pdf iconfuran-bearing_pyrazolopyridine.pdf
Moustafa, E. A., N. N. E. El‐Sayed, M. A. Fouad, A. M. El Kerdawy, M. A. F. Ezzat, and H. A. Allam, " Quinolone as a Privileged Scaffold: A Brief Overview on Early Classical and Recent Advanced Synthetic Pathways, Innovative Neuroprotective Potential, and Structure‐Activity Relationships", Drug Development Research, vol. 86, issue 5, pp. 70132, 2025.
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Mogheith, S. M., H. A. Allam, M. A. F. Ezzat, T. E. Fandy, I. Khan, D. Dawud, Z. A. Y. Elmageed, A. Albohy, H. I. Ali, and S. Mohamady, " Design, novel one-pot green synthesis, and biological evaluation of pyrazolopyridine-congeners selectively targeting HER2+ breast cancer", Bioorganic Chemistry, vol. 163, pp. 108681 , 2025.
application/pdf iconsamar_paper.pdf
Adardour, M., A. - H. M. Mustafa, M. Oubahmanea, M. A. Lahcen, E. M. Seif, M. A. F. Ezzat, E. Zaballos-García, J. T. Mague, I. Hdoufane, D. Cherqaoui, et al., "Design, synthesis and molecular modeling of new Pyrazolyl-Benzimidazolone hybrids targeting breast Cancer", Bioorganic Chemistry, vol. 157, pp. 108269 , 2025.
application/pdf iconpyrazolyl-benzimidazole_morocco.pdf
El-Mageed, M. A. M. A., M. A. F. Ezzat, S. A. Moussa, G. F. Elmasry, and H. A. Abdel-Aziz, "Rational design, synthesis and computational studies of multi-targeted anti-Alzheimer’s agents integrating coumarin scaffold", Bioorganic Chemistry, vol. 154, pp. 108024 , 2025.
application/pdf iconantialzheimer_coumarin.pdf
Mogheith, S. M., H. A. Allam, M. A. F. Ezzat, and S. Mohamady, "Overview on Synthetic Strategies and Bioactivities of Pyrazolopyridines", Egyptian Journal of Chemistry , vol. 67, issue 12, pp. 513 - 535, 2024.
application/pdf iconreview.pdf
Hassan, A. M. A., M. El-Hussieny, N. F. El-Sayed, M. A. Fouad, E. F. Ewies, and M. A. F. Ezzat, "Synthesis and characterization of new tetrakisphosphonic acid derivatives as FPPS inhibitors and evaluation of their anti osteoclastogenic potential for prevention of osteoporosis", Medicinal Chemistry Research, vol. 33, pp. 1167–1177, 2024.
application/pdf iconosteoporosis.pdf
Moustafa, E. A., H. A. Allam, M. A. Fouad, N. A. H. E. D. N. A. S. S. E. R. E. I. D. EL-SAYED, A. E. M. Kerdawy, C. Wagner, H. A. Abdel-Aziz, and M. A. F. Ezzat, "Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer’s disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation", Bioorganic Chemistry, vol. 146, pp. 107324, 2024.
application/pdf iconnovel_quinolin-2-one_derivatives_as_potential_gsk-3b.pdf
Mohammed, E. R., E. M. Seif, T. M. Sakr, M. A. F. Ezzat, H. A. Abdel-Aziz, B. M. Essa, and H. S. Ibrahim, " Synthesis of S-alkylated oxadiazole bearing imidazo[2,1-b]thiazole derivatives targeting breast cancer: In vitro cytotoxic evaluation and in vivo radioactive tracing studies", Bioorganic Chemistry, vol. 153, pp. 107935 , 2024.
application/pdf iconmda-mb.pdf
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