Publications

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2023
Elbialy, N. A., H. K. A. Elhakim, M. H. Mohamed, and Z. A. I. N. A. B. ZAKARIA, "Evaluation of the synergistic effect of chitosan metal ions (Cu2+/Co2+) in combination with antibiotics to counteract the effects on antibiotic resistant bacteria", RSC Advances, vol. 13, issue 1, pp. 17978-17990, 2023.
application/pdf iconevaluation_of_the_....pdf
Khafaga, D. S. R., A. M. El-Khawaga, R. A. E. Mohammed, and H. E. B. A. K. ABDELHAKIM, "Green synthesis of nano-based drug delivery systems developed for hepatocellular carcinoma treatment: a review", Molecular Biology Reports, vol. 50, issue 1, pp. 10365-10379, 2023.
application/pdf iconGreen synthesis of nano-based drug delivery systems developed for hepatocellular carcinoma treatment: a review
Shadeed, S. H., M. A. El-Desouky, N. A. H. L. A. S. KOTB, and H. K. A. Elhakim, "Synergistic Effect of Cetuximab in Combination with Bee Venom: A Novel Approach for the Treatment of Colon Cancer", Biointerface Research in Applied Chemistry, vol. 13, issue 1, pp. 178-192, 2023.
Sultan, N. S., H. K. A. Elhakim, A. A. Shoukry, and F. B. Rashidi, "Synthesis, Characterization, and Biological Evaluation of Cu(II) Complexes Containing Triflupromazine with Glycine and Histidine", Chemistry and Biodiversity , vol. 20, issue 1, pp. 1-13, 2023.
2022
Nagy, R. A. A., H. K. A. Elhakim, M. H. Mohamed, M. Afify, M. A. D. E. El-Maksoud, A. R. H. Farrag, D. S. R. Khafaga, and M. M. Eid, " Anticancer effect of Sorafenib-loaded iron oxide nanoparticles and bee venom on some genes expression in hepatocellular carcinoma ", Egyption journal of chemistry , vol. 65, issue SI13B , pp. 1477 - 1487, 2022.
application/pdf iconanticancer_effect_of_sorafenib-loaded_iron.pdf
Ragab, H. M., F. A. Attaby, N. Abd El Maksoud, M. A. Amin, H. E. B. A. K. ABDELHAKIM, and W. A. El Aziz, "Association between rs738409 and rs139051 SNPs of the PNPLA3 gene and the presence of NAFLD", Egyption journal of chemistry , vol. 65, issue 9, pp. 127 - 137, 2022.
application/pdf iconassociation-between-rs738409-and-rs139051-snps-of-the-pnpla3-gene-and-the-presence-of-nafldegyptian-journal-of-chemistry.pdf
Khedr, M., E. M. Desouky, A. Shafei, R. Mostafa, A. Hasanin, E. Habib, H. Abdelhakim, and M. Mitboli, "Cardioprotective Effect Of Cyanidin-3-O-Glucosidein Ischemic Heart Is Mediated Via Inhibition Of Autophagy ", Egyption journal of chemistry , vol. 65, issue 5, pp. 179 - 186 , 2022.
application/pdf iconcardioprotective-effect-of-cyanidin3oglucosidein-ischemic-heart-is-mediated-via-inhibition-of-autophagyegyptian-journal-of-chemistry.pdf
Khafaga, D. S. R., M. M. Eid, M. D. A. El-Maksoud, M. Afify, M. H. Mohamed, A. R. H. Farrag, R. A. A. Nagy, and H. K. A. Elhakim, "Green Synthesis of Zinc oxide Nanocomposite Using Fusarium oxysporum and Evaluation of the Anticancer Effect on Hepatocellular Carcinoma ", Egyption journal of chemistry , vol. 65, issue 4, pp. 192-207, 2022.
application/pdf icongreen_synthesis_of_zinc_oxide_nanocomposi.pdf
2021
Ahmed, D. E., F. B. Rashidi, H. E. B. A. K. ABDELHAKIM, A. M. R. S. MOHAMED, and H. M. M. Arafa, "An in vitro cytotoxicity of glufosfamide in HepG2 cells relative to its nonconjugated counterpart", Journal of the Egyptian National Cancer Institute, pp. 22-33, 2021.
application/pdf iconahmed2021_article_aninvitrocytotoxicityofglufosf.pdf
2020
Saleh, L., E. Ragab, H. K. A. Elhakim, S. Mohamed, and Z. Zakaria, " Evaluation of Anticancer Activities of Gallic Acid and Tartaric Acid Vectorized on Iron Oxide Nanoparticles", Drug Delivery Letters , vol. 10, issue 2, pp. 123-132, 2020. evaluation_of_anticancer_...pdf
application/pdf iconevaluation_of_anticancer_...pdf
Fahim, Y. A., N. E. Sharaf, I. W. Hasani, E. A. Ragab, and H. E. B. A. K. ABDELHAKIM, "Assessment of Thyroid Function and Oxidative Stress State in Foundry Workers Exposed to Lead", Journal of Health & Pollution, vol. 10, issue 27, pp. 200903, 2020. assessment_of_thyroid_function_and_oxidative_stress_state.pdf
application/pdf iconassessment_of_thyroid_function_and_oxidative_stress_state.pdf
Abdelhakim, H. K., E. R. El-Sayed, and F. B. Rashidi, "Biosynthesis of zinc oxide nanoparticles with antimicrobial, anticancer, antioxidant and photocatalytic activities by the endophytic Alternaria tenuissima", Journal of Applied Microbiology, vol. 128, issue 6, pp. 1634-1646, 2020.
application/pdf iconbiosynthesis_of_zinc_oxide_nanoparticles_with_antimicrobial.pdf
El-Sayed, E. - S. R., H. E. B. A. K. ABDELHAKIM, and Z. A. I. N. A. B. ZAKARIA, "Extracellular biosynthesis of cobalt ferrite nanoparticles by Monascus purpureus and their antioxidant, anticancer and antimicrobial activities: Yield enhancement by gamma irradiation", Materials Science & Engineering C, vol. 107, pp. 110318, 2020.
application/pdf iconextracellular_biosynthesis_of_cobalt_ferrite_nanoparticles_by_monascus.pdf
Qotob, M. A., M. A. Nasef, H. K. A. Elhakim, O. G. Shaker, N. R. Habashy, and I. A. Abdelhamid, "INTEGRATED EFFECT OF PLANT GROWTH REGULATORS WITH BORON SOURCES ON SOME BIOLOGICAL PARAMETERS OF SUGAR BEET", Plant Archives, vol. 20, issue 1, pp. 1783-1793, 2020.
application/pdf iconintegrated_effect_of_plant_growth_regulators_with.pdf
Mohamed, M. F., H. K. A. Elhakim, A. A. Saddiq, and I. A. Abdelhamid, "A novel inhibitor, 2-cyano-3-(1-phenyl-3-(thiophen- 2-yl)-pyrazol-4-yl)acrylamide linked to sulphamethoxazole, blocks anti-apoptotic proteins via molecular docking and strongly induced apoptosis of HCT116 cell line by different molecular tools", Arabian Journal of Chemistry, vol. 13, issue 7, pp. 5978–5995, 2020.
application/pdf icona_novel_inhibitor_2-cyano-3-1-phenyl-3-thiophen-.pdf
El-Sayed, E. R., A. S. Ahmed, and H. K. Abdelhakim, "A novel source of the cardiac glycoside digoxin from the endophytic fungus Epicoccum nigrum: isolation, characterization, production enhancement by gamma irradiation mutagenesis and anticancer activity evaluation", Journal of Applied Microbiology, vol. 128, pp. 747--762, 2020.
application/pdf icona_novel_source_of_the_cardiac_glycoside_digoxin_from_the.pdf
Muhammed, R. E., M. A. El-Desouky, S. B. Abo-Seda, A. A. Nahas, H. K. A. Elhakim, and M. I. Alkhalaf, "The protecting role of Moringa oleifera in cypermethrin-induced mitochondrial dysfunction and apoptotic events in rats brain", Journal of King Saud University – Science, vol. 32, pp. 2717–2722, 2020.
application/pdf iconthe_protecting_role_of_moringa_oleifera_in_cypermethrin-induced.pdf
Qotob, M. A., M. A. Nasef, H. K. A. Elhakim, O. G. Shaker, and I. A. Abdelhamid, "Revisiting of chemical fertilizers by using suitable plant growth regulators and nano fertilizer", global scientific journals , vol. 8, issue 11, pp. 1896-1907, 2020.
application/pdf iconrevisiting_of_chemical_fertilizers_by_using_suitable_plant_growth_regulators.pdf
Ibrahim, K. A. E. - M., S. M. Abdelrahman, H. K. A. Elhakim, and E. A. Ragab, "Single or combined exposure to chlorpyrifos and cypermethrin provoke oxidative stress and downregulation in monoamine oxidase and acetylcholinesterase gene expression of the rat’s brain", Environmental Science and Pollution Research, vol. 27, pp. 12692–12703, 2020.
application/pdf iconsingle_or_combined_exposure_to_chlorpyrifos_and_cypermethrin_provoke.pdf
El‑Sayed, E. ‑S. R., H. E. B. A. K. ABDELHAKIM, and A. S. Ahmed, "Solid‑state fermentation for enhanced production of selenium nanoparticles by gamma‑irradiated Monascus purpureus and their biological evaluation and photocatalytic activities", Bioprocess and Biosystems Engineering, vol. 43, pp. 797–809, 2020.
application/pdf iconsolid-state_fermentation_for_enhanced_production_of_selenium.pdf
Zidan, A. E., M. A. El-Desouky, A. O. Lotfy, H. K. Abdelhakim, and E. A. Sultan, "VITAMIN D STATUS AND VARIOUS PREDICTORS IN EGYPTIAN ADOLESCENT FEMALES", Plant Archives, vol. 20, issue 2, pp. 2117-2121, 2020.
application/pdf iconvitamin_d_status_and_various_predictors_in_egyptian.pdf
2019
Ibrahim, K. A., S. A. Khwanes, M. A. El-Desouky, and H. K. A. Elhakim, "Propolis relieves the cardiotoxicity of chlorpyrifos in diabetic rats via alleviations of paraoxonase-1 and xanthine oxidase genes expression", Pesticide Biochemistry and Physiology, vol. 159, issue 0048-3575, pp. 127-135, 2019. propolis_relieves_the_cardiotoxicity_of_chlorpyrifos_in_diabetic_rats_via_2.pdf
application/pdf iconpropolis_relieves_the_cardiotoxicity_of_chlorpyrifos_in_diabetic_rats_via_2.pdf
Azab, S. M., H. K. A. Elhakim, and A. M. Fekry, "The strategy of nanoparticles and the flavone chrysin to quantify miRNA-let 7a in zepto-molar level: its application as tumor marker", Journal of Molecular Structure, vol. 1196, issue 15, pp. 647-652, 2019.
application/pdf iconthe_strategy_of_nanoparticles_and_the_flavone_chrysin_to_quantify_mirna-let_7a_in.pdf
2018
Elhakim, H. K. A., S. M. Azabb, and A. M. Fekry, "A novel simple biosensor containing silver nanoparticles/propolis (bee glue) for microRNA let-7a determination", Materials Science & Engineering C, vol. C 92, issue 0928-4931, pp. 489-495, 2018. 1-s2.0-s0928493117348063-main.pdf
application/pdf icona_novel_simple_biosensor_containing_silver_nanoparticlespropolis_bee_glue.pdf
Elsayed, G. M., A. A. Fahmi, N. F. Shafik, R. A. A. Elshimy, H. A. K. Elhakeem, and S. A. Attea, "Study of DNA methyl transferase 3A mutation in acute myeloid leukemic patients", The Egyptian Journal of Medical Human Genetics, vol. 19, pp. 315–319, 2018. study_of_dna_methyl_transferase_3a_mutation_in_acute_myeloid_leukemic_2.pdf
application/pdf iconstudy_of_dna_methyl_transferase_3a_mutation_in_acute_myeloid_leukemic_2.pdf
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