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Background: Exercise is often recommended for patients with type 2 diabetes to improve physical conditioning and glycemic control. Objective: The purpose of this study was to evaluate the impact of circuit weight training on nitric oxide in type 2 diabetes mellitus. Subjects and methods: Forty type 2 diabetic women participated in the study, their ages ranged from 40-50 years. They were assigned randomly to two groups; 20 patient each: Group (A) received circuit weight training 20min and aerobic training 30min for 12 weeks, 3 sessions per week and with 30-60% of 1RM. Group (B) received aerobic training on treadmill 30min for 12 weeks, 3 sessions per week with moderate intensity using borg scale. Pre and post 12 weeks blood samples were taken from all subjects. Results: this study revealed significant increase in NO level, reduction in 2h post prandial Glucose and waist circumference after 12 weeks in group (A) but more than that occurred in group (B).Conclusions: It was concluded that circuit weight training had highly significant increase in NO level, reduction in 2HPP and waist circumference so this study supports the value of circuit weight training in the management of type 2 diabetes.

Key words: Type 2 diabetes mellitus, circuit weight training, nitric oxide.