Background: Upper extremity impairment as a deficit, affects the daily lives’ of the sufferers. Objective: To investigate the effect of
bihemispheric tDCS on functional recovery of the affected upper extremity in chronic stroke patients. Patients and methods: Forty
chronic stroke patients were allocated randomly to receive 10 consecutive sessions of either 1) simultaneous bihemispheric transcranial
direct current stimulation (tDCS) and constraint induced movement therapy (CIMT) (study group) or 2) simultaneous sham stimulation
and CIMT (control group). Outcome measures include changes in affected upper extremity motor impairment (Motricity Index (MI),
Fugl-Meyer Upper Extremity Motor Assessment (UE-FM)) and motor activity (Action Research Arm Test (ARAT)) assessments.
Results: The improvement of motor function (MI, ARAT and UE-FM scores) were significantly greater in the real stimulation group
than the sham group (p = 0.002, 0.01 and <0.001 respectively). Conclusions: Bihemispheric tDCS can improve the recovery of motor
functions in chronic stroke