Performing vitreous biopsy by perfluorocarbon-perfused vitrectomy.

Citation:
Quiroz-Mercado, H., J. Rivera-Sempertegui, T. A. Macky, P. Navarro-López, L. Griselda-Alvarez, N. Ibarra-Ponce, and D. Moreno-Páramo, "Performing vitreous biopsy by perfluorocarbon-perfused vitrectomy.", American journal of ophthalmology, vol. 140, issue 6, pp. 1161-3, 2005 Dec. copy at www.tinyurl.com/yy7jxmf9

Abstract:

PURPOSE: To evaluate the safety and efficacy of perfluorocarbon-perfused vitrectomy (PCPV) as a novel technique in obtaining a large undiluted vitreous biopsy.

DESIGN: Cross-sectional interventional study.

METHODS: Patients with undiagnosed posterior uveitis scheduled for vitreous biopsy underwent PCPV. A syringe containing 5 ml of perfluorocarbon liquid (PCL) was connected to the infusion line. Aspiration of the central and superior vitreous was initiated with simultaneous infusion of the PCL.

RESULTS: Twenty eyes of 20 patients were included in this study. The mean +/- SD amount of PCL used in each eye was 4.50 +/- 0.69 ml. The volume of vitreous sample obtained in each eye was 2.25 +/- 0.413 ml. No complications occurred.

CONCLUSIONS: PCPV is a safe and effective method for obtaining large undiluted vitreous biopsy.