Bipseudophakia: clinicopathological correlation of a dropped lens.

Izak, A. M., D. J. Apple, L. Werner, R. H. Trivedi, S. K. Pandey, T. A. Macky, J. M. Schmidbauer, and P. Marsh, "Bipseudophakia: clinicopathological correlation of a dropped lens.", Journal of cataract and refractive surgery, vol. 28, issue 5, pp. 874-82, 2002 May. copy at


PURPOSE: To examine postmortem human globes containing an anterior chamber and a posterior chamber intraocular lens (IOL).

SETTING: Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Charleston, South Carolina, USA.

METHODS: The globes were sectioned at the equator, and the anterior and posterior segments were macroscopically examined. Gross photographs were taken using the Miyake-Apple posterior photographic technique. Histological sections were cut and stained with hematoxylin and eosin, periodic acid-Schiff, and Masson's trichrome.

RESULTS: Histopathological findings included a large Soemmering's ring, a tear in the posterior capsule, 1 haptic of the anterior chamber IOL displaced into the iridectomy, thin and atrophic corneal epithelium, separation of Bowman's layer and stroma by fibrovascular tissue, and atrophy of the retinal ganglion cell layer and nerve fiber layer.

CONCLUSION: In cases in which secondary IOL implantation is indicated, removing the dislocated IOL appears to be a reasonable choice.