Nutraceuticals for alzheimer's disease

Kotta, S., V. K. A. Shirin, R. Sankar, S. M. Badr-Eldin, H. M. Aldawsari, N. A. Alhakamy, and P. K, "Nutraceuticals for alzheimer's disease", Bioactive Nutraceuticals for Brain Disorders: Nova Science Publishers, Inc., 2021.


Nutraceuticals are compounds of mainly plant origin and are found applicable for the therapy of a largenumber of diseases. They possess important pharmacological actions such as anti-inflammatory,antioxidant, and neuroprotectiveactivities. Alzheimer's disease (AD) is a neurodegenerative disordermostly found in aged groups and is connected with the amyloid-beta peptide and neurofibrillary tangleformation. Even though many drugs are available for the treatment, a complete cure for this disease isnot yet available. This highlights the importance of dietary and lifestyle habits for disease modification.Many compounds of plant origin have been identified to possess potent activity against the development of AD. These nutraceuticals can play major roles in different stages through different molecular targets of AD both in neuronal as well as biochemical levels. These substances have morethan one mechanism in controlling various signaling pathways in the pathogenesis of AD. The chapter gives a detailed description of nutraceuticals that have been explored to date for their beneficiary role in AD. The intake of these food supplements can provide significant benefits in AD as evidenced by different in vitro and in vivo experiments. The food mentioned in this chapter is a proven remedy against AD. So the inclusion of these agents in the daily diet will produce a positive impact on thisneurodegenerative disease of the elderly