Publications

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2021
Badawy, S. E. A., H. A. Ogaly, R. M. Abd-Elsalam, and A. A. Azouz, "Benzyl isothiocyanates modulate inflammation, oxidative stress, and apoptosis via Nrf2/HO-1 and NF-κB signaling pathways on indomethacin-induced gastric injury in rats", Food & Function DOI: 10.1039/D1FO00645B, vol. 12, issue 13, pp. 6001-6013, 2021.
Abd-Elsalam, R. M., and F. I. O. F. K. A. M. M. & A. Shymaa A. El Badawy, Hanan A. Ogaly, "Eruca sativa seed extract modulates oxidative stress and apoptosis and up-regulates the expression of Bcl-2 and Bax genes in acrylamide-induced testicular dysfunction in rats", Environmental Science and Pollution Research, 2021, 2021.
Emam, S. R., A. A. A. A. S. E. Abd-Elsalam, R. M., E. S. A. Badawy, and I. E. M. Y. S. H. M A Ibrahim, B B Hassan, "Linum usitatissimum seeds oil down-regulates mrna expression for the steroidogenic acute regulatory protein and cyp11a1 genes, ameliorating letrozole-induced polycystic ovarian syndrome in a rat model", Journal of Physiology and Pharmacology, 2021, 72(1), 2021.
Ola M Farag, R. M. Abd-Elsalam, and S. E. B. M. A. C. G. A. A. Hanan A Ogaly, Sara E Ali, "Metabolomic Profiling and Neuroprotective Effects of Purslane Seeds Extract Against Acrylamide Toxicity in Rat’s Brain", Neurochemical Research DOI: 10.1007/s11064-020-03209-6, 2021.
Asmaa A Azouz, Sara E Ali, R. A. - E. S. E. M. G. S. E. M. R. K. H., C. G. L. Muhammed A Alsherbiny, Bardes B Hassan, and S. E. A. Badawy, "Modulation of steroidogenesis by Actaea racemosa and vitamin C combination, in letrozole induced polycystic ovarian syndrome rat model: promising activity without the risk of hepatic adverse effect", Chinese Medicine (United Kingdom), 2021, 16(1), 36, 2021.
Ali, S. E., S. A. El Badawy, A. A. M. G. R. A. - E. A. K. M. Sherif H Elmosalamy, Shimaa R Emam, and B. H. B. Marwa Y Issa, "Novel promising reproductive and metabolic effects of Cicer arietinum L. extract on letrozole induced polycystic ovary syndrome in rat model", Journal of Ethnopharmacology, 2021, 278, 114318, 2021.
Ola M. Farag, Reham M. Abd-Elsalam, Shymaa A. El Badawy, and M. A. K. A. A. & A. Hanan A. Ogaly, "Portulaca oleracea seeds’ extract alleviates acrylamide-induced testicular dysfunction by promoting oxidative status and steroidogenic pathway in rats", BMC Complementary Medicine and Therapies, 2021, 21(1), 122, 2021.
2020
Galal Khamis, Manar Hassan, M. M. M. I. R. A. - E. A. M., S. A. E. Badawy, A. A. Azouz, and M. Galal, "Innovative application of helium-neon laser: enhancing the germination of Adansonia digitata and evaluating the hepatoprotective activities in mice", Environmental Science and Pollution Research, 2020, 27(21), pp. 26520–26531, 2020.
A. Amer, S. A. E. Badawy, W. A. -elsalamH. M. S. Saber, O. Farid, and M. Amer, "Pharmacokinetics of tetracycline and tetracycline loaded nanoemulsion formula in Rabbits", Advances in Animal and Veterinary Sciences, 2020, 8(2), pp. 130–139, 2020.
2019
Badawy, S. E. A., A. M. M. Amer, G. M. Kamel, and P. D. Constable, "Pharmacokinetics and pharmacodynamics of intramammary cefquinome in lactating goats with and without experimentally induced Staphylococcus aureus mastitis", Journal of Veterinary Pharmacology and Therapeutics, 2019, 42(4), pp. 452–460, 2019.
Seham S El-Din El-Hawary, Soheir M El Zalabani, N. S. M. I. F. W. M. A. A., S. E. A. Badawy, and M. S. Nariman El Sayed Mahdy, Aziz Yasri, "Phenolic constituents of Chrysophyllum oliviforme L. Leaf down-regulate TGF-β expression and ameliorate CCL4-induced liver fibrosis: Evidence from in vivo and in silico studies", Antioxidants, 2019, 8(12), 646, 2019.
2018
Alsherbiny, M. A., S. E. A. Badawy, H. S. Elbedwey, S. M. Ezzat, F. S. Elsakhawy, and M. A. Abdel-Kawy, "Comparative molluscicidal and schitosomicidal potentiality of two Solanum species and its isolated glycoalkaloids. ", Pharmacognosy Research, vol. 10, issue 1, pp. 113-117, 2018.
AA, M., H. MWH, E. B. SA, and C. PD, "Plasma calcium concentrations are decreased at least 9 hours before parturition in multiparous Holstein-Friesian cattle in a herd fed an acidogenic diet during late gestation.", Journal of dairy science, vol. 101, issue 2, pp. 1365-1378., 2018.
2015
Badawy, E. S. A., A. M. Amer, G. M. Kamel, K. M. Eldeib, and P. D. Constable, "Comparative pharmacokinetics using a microbiological assay and high performance liquid chromatography following intravenous administration of cefquinome in lactating goats with and without experimentally induced Staphylococcus aureus mastitis", Small Ruminant Research, vol. 133, pp. 67 - 76, 2015. AbstractWebsite

Abstract Cefquinome pharmacokinetic values were compared using a microbiological assay (MA) and high performance liquid chromatography (HPLC) in lactating goats with and without experimentally induced Staphylococcus aureus mastitis. Five healthy lactating goats received an İV\} injection of cefquinome sulfate (75 mg, equivalent to cefquinome at 3.0 mg/kg BW). The same dose of cefquinome sulfate was administered İV\} after clinical mastitis was induced by intracisternal infusion of 100 cfu of S. aureus \{ATCC\} 29213. Jugular venous blood and milk samples were obtained periodically after cefquinome administration in healthy and mastitic goats, and plasma and skimmed milk cefquinome concentrations were determined using \{MA\} and HPLC. Deming regression and Bland-Altman plots indicated equivalence of \{MA\} and HPLC. Both \{MA\} and \{HPLC\} analytical methodologies yielded statistically similar mean values for the cefquinome concentration-time relationship in plasma and skimmed milk and similar values for almost all calculated pharmacokinetic indices; however, \{HPLC\} had a lower limit of quantification \{LOQ\} and coefficient of variation, and a higher correlation coefficient for standard curves. Noncompartmental pharmacokinetic (PK) analysis indicated that mastitis decreased the mean residence time of cefquinome in plasma but did not change the mean residence time in skimmed milk. Skimmed milk cefquinome concentrations after İV\} injection remained below the \{MIC\} (0.25 ?g/mL) for S. aureus at every measurement time except at 6 h after injection, and clinical mastitis remained present for at least 5 days in treated goats. In conclusion, \{MA\} provides a simple, practical and inexpensive method for measuring cefquinome concentrations in plasma and skimmed milk samples from goats, while, \{HPLC\} proved to be more sensitive, specific and accurate. Mastitis increased cefquinome clearance compared to healthy goats which emphasizes the importance of performing pharmacokinetic studies in infected animals. Additional studies are required to determine whether intramammary cefquinome is effective in treating S. aureus mastitis in goats.

2014
El Badawy, S. A., A. M. M. Amer, P. D. Constable, and A. M. Guda, "Effect of tulathromycin on abomasal emptying rate in healthy lactating goats", Small Ruminant Research, vol. 121, no. 2: Elsevier, pp. 395–399, 2014. Abstract
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2012
Amer, A. M. M., P. D. Constable, A. Goudah, and S. A. El Badawy, "Pharmacokinetics of tulathromycin in lactating goats", Small Ruminant Research, vol. 108, no. 1: Elsevier, pp. 137–143, 2012. Abstract
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