Water-soluble Derivatives of Chitosan as A Target Delivery System of 99mtc to some Organs in Vivo for Nuclear Imaging And Biodistribution
- Citation:
- Hawary, D. L., M. A. Motaleb, H. Farag, O. W. Guirguis, and M. Z. Elsabee, "Water-soluble Derivatives of Chitosan as A Target Delivery System of 99mtc to some Organs in Vivo for Nuclear Imaging And Biodistribution", J. Radioanal. Nucl. Chem., vol. 290, issue 3, pp. 557-567, 2011.
Abstract:
Carboxymethyl chitosan, (CMC), and N-laurylcarboxymethyl chitosan (LCMC), have been prepared as water soluble derivatives of chitosan. These biodegradable chitosan derivatives were characterized and investigated for nuclear imaging and body distribution. They were labeled with 99mTc to use them as targeted delivery to some organs in vivo for nuclear imaging and to follow their biodistribution within the body. The factors controlling the labeling efficiency have been investigated.
Notes:
n/a