Synthesis and Characterization of some Potential Antitumorpalladium(II) Complexes of 2-aminomethylbenzimidazoleand amino Acids

Citation:
A.El-Sherif, A., "Synthesis and Characterization of some Potential Antitumorpalladium(II) Complexes of 2-aminomethylbenzimidazoleand amino Acids", Coordination Chemistry, 2011.

Abstract:

The stoichiometry and stability constants of the complexes formed between [Pd (AMBI)(H2O)2]2+, (AMBI = 2-(aminomethyl)-benzimidazole) with some selected bio-relevant ligands containing different functional groups, were investigated at 25 0C and 0.1 M ionic strength. The ligands used are imidazole, cysteine, glutathione (GSH), threonine, aspartic acid, 1,1-cyclobutane dicarboxylic acid (CBDCA) and lysine. The stoichiometry and stability constants of the formed complexes are also reported, and the concentration distribution of the various complex species was evaluated as a function of pH. The results show ring opening of CBDCA and monodentate

Notes:

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