Synthesis and Antimicrobial Evaluation of Some New Tetrahydropyrimidine Derivatives

Citation:
Mabkhot, Y. N., N. A. Kheder, and A. M. Farag, "Synthesis and Antimicrobial Evaluation of Some New Tetrahydropyrimidine Derivatives", Heterocycles, 2011.

Abstract:

The utility of 1,2,3,4-tetrahydropyrimidine-5-carboxylate (1a,b), and 1,2-dihydropyrimidine-5-carboxylate (2) in the synthesis of some new functionalized pyrimidine derivatives such as 6-(2-(dimethylamino)vinyl)-1,2,3,4-tetrahydropyrimidine,6-(1-cyano -2-(phenylamino)-2-thioxoethyl)-1,2,3,4-tetrahydropyrimidine and 4,6-distyryl-1,2-dihydropyrimidine derivatives is reported. Antimicrobial evaluation of some selected examples from the synthesized products was carried out and showed promising results.

Notes:

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