Basic Science Sector

Citation:

Shoukry, M. M., and A. A. El-Sherif, "The palladium(II)-picolylamine promoted hydrolysis of amino acid esters; kinetic evidence for inter- and intramolecular mechanisms", Progress in reaction kinetics and mechanisms., 2011.

Abstract:

The hydrolysis of amino acid ester is promoted by the palladium(II) complex [Pd(Pic)]2+ (Pic = 2-picolylamine). The reaction has been studied by pH-stat technique. The overall PdII chelate promoted hydrolysis of the amino acid esters as glycine and alanine ethyl esters may be accounted by inter- and intramolecular mechanisms. The kinetic data for histidine and methionine methyl esters are fitted assuming that hydrolysis proceeds by intermolecular mechanism only. The rate enhanecement compared with the free ester is discussed in terms of the structure of the complex. Activation parameters associated with the hydrolysis have been determined and discussed.

Notes:

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