Comparative Studies on the Influences of Juniperus Phoenicea and Hyphaene Thebaica as Hypoglycemic Factors In Diabetic Rats
- Citation:
- Abdel-Rahim, E. A., H. S. El-Beltagi, and S. A. S. Fayed, "Comparative Studies on the Influences of Juniperus Phoenicea and Hyphaene Thebaica as Hypoglycemic Factors In Diabetic Rats", Advances in Food Sciences, vol. 33, 2011.
Abstract:
The effects of methanolic extracts of Juniperus phoenicea and Hyphaene thebaica on carbohydrate metabolism of male streptozotocin-treated diabetic rats were studied. Blood glucose, liver glycogen and the activities of lactate dehydrogenase (LDH), hexokinase (HK) and pyruvate kinase (PK) as well as the contents of pyruvate and lactate were determined in brain, liver and kidney tissues of the experimental animals. The ingestion of both methanolic extracts significantly reduced the high level of blood glucose but elevated the liver glycogen content of the diabetic rats. PK activity reached the highest values in liver and kidneys but brain showed the minimal stimulation. HK activity had nearly the same trend as that of PK. In case of LDH, the activity was also stimulated in the examined organs of the treated animals. In addition, pyruvate contents were significantly decreased.
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