Basic Science Sector

Citation:

Hassaneen, H. M. E., "Chemistry of Enaminone of 1-Acetylnaphthalene using chitosan as green catalyst under microwave irradiation", Molecules. 16(1), 2011.

Abstract:

Enaminone 1 was reacted with hydrazonoyl halides 2a-d to yield 3,4-disubstituted pyrazoles 6a-d and coupling with arenediazonium chlorides to afford the 2-(arylhydrazono)-3-(1-naphthalenyl)-3-oxopropionaldehydes 13a-c. Compounds 13 could be utilized for synthesis of variety of arylpyrazoles, arylazolopyrimidines, and pyridazinones via reaction with hydrazines, aminoazoles, and active methylene derivatives, respectively. The foregoing reactions were carried out with chitosan as basic ecofriendly catalyst under conventional heating as well as pressurized microwave irradiation and a comparative study was employed.

Notes:

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