Basic Science Sector

{2,4-D, dicamba and 4-CPA with auxin-like activity have been intensively used in agriculture, for the control of unwanted broadleaf weeds. An analytical method involving HPLC coupled with UVD was developed for the simultaneous analysis of these three analytes in Chinese cabbage, apple and pepper fruits (representative non-fatty samples) and brown rice and soybean (representative fatty samples) using liquid-liquid partitioning and column cleanup procedures. The residues were confirmed via tandem mass spectrometry (MS/MS) in ion electrospray ionization (ESI) mode. The standard curves were linear over the range of the tested concentrations (0.25-10?microg/mL), as shown by a marked linearity in excess of 0.9999 (r(2) ). The average recoveries (mean

In a continuation of our earlier work, a multiresidual analytical method using 48 frequently used neutral pesticides in a water matrix was developed and validated in this study. The samples were extracted with dichloromethane and the pesticides were analyzed via GC-NPD followed by confirmation with GC-MS. Good linearity was detected over a concentration range of 0.01-1.0 microg/mL with correlation coefficients (r(2) ) in excess of 0.982. The recoveries were measured between 70.7 and 111.4% for the majority of the targeted pesticides with relative standard deviations (RSDs) of less than 20%. The LODs and LOQs were in ranges of 0.1-2 and 0.33-6.6 microg/L, respectively. A total of 66 water samples were collected from different locations in Yeongsan and the Sumjin River, Republic of Korea, and were analyzed in accordance with the developed method. None of the water samples were determined to contain any of the targeted pesticides. The method has been shown to be simpler, faster, and more cost-effective than the method established by the Environmental Protection Agency (EPA).

A simple, facile, efficient and one pot three-component procedure for the synthesis of pyrazolo[1,5-a]pyrimidines, triazolo[1,5-a]pyrimidines and pyrimido[1,2-a]benzimidazoles ring systems incorporating phenylsulfonyl moiety was developed via the reaction of 1-aryl-2-(phenylsulfonyl) ethanone derivatives 1a-d with the appropriate heterocyclic amine and triethyl orthoformate and evaluated as Aurora-A kinase inhibitors. The cytotoxic activity of the newly synthesized compounds against HST116 colon tumor cell line was investigated.2,7-Diphenyl-6-(phenylsulfonyl)pyrazolo [1,5-a] pyrimidine (4b) and its p-methoxy analogue 4c were found to be equipotent to Doxorubicin as a reference drug. Molecular modeling study was carried out in order to rationalize the in vitro anti-tumor results.

Silica-coated Fe2O3 nanoparticles were synthesized as carriers for the covalent immobilization and release of antimicrobial drug sparfloxacin (SPFX). SPFX-loaded nanoparticles exhibited time-dependent drug release, with no measurable in vitro cytotoxicity, making the drug@nanoparticle conjugates potentially relevant for nanomedicine applications.

In this work the retardation of Ehrlich tumor growth implanted in mice was studied by employing 4.5 Hz magnetic field. Eighty female Balb/c mice were used, twenty as normal group; the other sixty mice were inoculated with Ehrlich tumor, then they were divided equally into three groups namely A, B and C.Group A (control group) animals were not exposed to the magnetic field .The tumors in the thigh of the animals of group B were exposed to 4.5 Hz, 2 Gauss square wave magnetic field by using a small solenoid connected to a power square wave generator. Group C animals were whole body exposed inside a large solenoid to 4.5 Hz, 2 Gauss square wave magnetic field.Both groups B & C were exposed for a period of 2 weeks at a rate 2 hours per day. Tumor volume, survival period, histological examination and dielectric relaxation of the tumor were measured to investigate the activity of the tumor of the exposed and the unexposed animals. The results indicated that exposing the tumor tissue to 4.5 Hz square wave magnetic field for 2 weeks at a rate 2 hours/day inhibited tumor growth and increased the survival period of the animals. However, group B showed more improvements than did group C. This was attributed to some distortions in the square waveform in the large solenoid (group C). By comparing data from current and previous work, it was concluded that the use of magnetic waves showed better results over previously published work using amplitude modulated electromagnetic waves with the same frequency.

A total of 208 cattle were randomly selected among slaughter houses, household and livestock farms to determine the prevalence of fascioliasis. Epidemiological studies on fascioliasis of cattle were undertaken in such localities under different climatic conditions existing in Ladakh region of Jammu and Kashmir State. Infection rate was 51.42%, 27.69% and 21.91% in slaughtered, livestock farm and household cattle, respectively. Significant variations were observed in the prevalence with respect to various host factors and the climate of the study area. Overall, the highest seasonal prevalence (45.19%) in all types of cattle was recorded during wet season while as only (24.40%) was recorded during the dry season. It was noticed that a higher infection rate was recorded in young cattle ages (0- 2 years) (40.02%) than in adult ones (28.04%) (3- 8 years). Moreover, the prevalence of infection in females was more (38.07%) than males (29.09%). It was also observed that the infection rate was high in comparatively low land areas (37.14%) as compared to high altitudes (30.09%). This study will provide necessary information regarding fascioliasis in cattle of Ladakh for their effective control and hence for a better production which will be beneficial resource to poor people where live stock rearing is one of the important sources of livelihood.

Three new thiadiazole derivatives (TDADs), namely, (I) N-[4-phenyl-5-(p-tolylimino)-4,5-dihydro-1,3,4-thiadiazole-2-yl] benzamide, (II) 2-acetyl-4-phenyl-5-(p-tolylimino)-4,5-dihydro-1,3,4- thiadiazole, and (III) Ethyl-4-phenyl-5-(p-tolylimino)-4,5-dihydro-1,3,4-thiadiazole-2-carboxylate, have been synthesized and used as additives to protect grade 1018 carbon steel from corrosion in naturally aerated 0.5 M NaCl solution (  3% by wt.). The techniques adopted include open circuit potential (OCP), potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) complemented

This paper represents an attempt to extend and improve the following result of Berkovich: Let G be a group of odd order. Let G = G1 G2 such that G1 and G2 are subgroups of G. If the Sylowp-subgroups of G1 and of G2 are cyclic, then G is p-supersolvable.

Soybean is a leguminous plant native to eastern Asia (Liu et al. 2008). Soybean is cultivated worldwide, with the U.S. being responsible for more than 50% of the world's production of this important food. Soybean grains are rich in protein content (see aminoacids composition, Table 1); therefore constitute a useful source of food.

Pd(deen)Cl2 and Pd(deen)(CBDCA) complexes, where deen = N,Ndiethylethylenediamine and CBDCA= 1,1-cyclobutanedicarboxylate, were synthesized and characterized by elemental analysis and spectroscopic techniques. The stoichiometry and stability of the complexes formed between various biologically relevant ligands (amino acids, peptides, DNA constituents and dicarboxylic acids) and [Pd(deen)(H2O)2]2+ were investigated at 25 ?C and 0.1 M ionic strength. The speciation diagrams of the complexes formed in solutions are evaluated. The mode of coordination of glycylglycine is investigated by spectrophotometric measurements. The equilibrium constants for the displacement of coordinated ligands as inosine, glycine or methionine by mercaptoethylamine are calculated. The results are expected to contribute to the chemistry of antitumour agents.

Schiff base ligands are prepared via condensation of pyridine?2,6?dicarboxaldehyde with 2?aminothiophenol (H2L1) and 2?aminobenzoic acid (H2L2), respectively. The ligands arecharacterized based on elemental analysis, mass, IR and 1H NMR spectra. Metal complexes arereported and characterized based on elemental analyses, IR, 1H NMR, solid reflectance,magnetic moment, molar conductance, and thermal analyses (TG, DTG and DTA). The molarconductance reveals that all the metal chelates are non?electrolytes except Th(IV) H2L2complex which is 1:1 electrolyte . IR spectra show that H2L1 and H2L2 ligands behave asneutral tridentate ligands and bind to the metal ions via the two azomethine N and pyridine N. From the magnetic and solid reflectance spectra, it is found that the geometrical structures ofthese complexes are octahedral (Cr(III)? and Fe(III)?H2L1 and H2L2, Th(IV)?H2L2 and Mn(II)?H2L1 complexes) and triagonal bipyramidal (Co(II), Ni(II), Cu(II), Cd(II) and UO2(II)?H2L1 andH2L2 and Mn(II)?H2L2 complexes). The thermal behaviour of these chelates is studied using TGand DTA techniques and the activation thermodynamic parameters are calculated usingCoats?Redfern method. The synthesized ligands and their metal complexes were screened fortheir biological activity against bacterial species (Escherichia coli, P. vulgavis, B. subtilis and S.pyogones) and fungi (F. solani, A. niger and A. liavus). The activity data show that the metalcomplexes have antibacterial and antifungal activity more than the parent Schiff base ligandsagainst one or more bacterial or fungi species.

New nanocomposite hybrid films of a well dispersed cerium disulphate Ce(SO4)2 nanoparticles into thepolyvinylpyrrolidone (PVP) matrix were prepared by a casting technique. The nanostructural nature and complex formation were investigated using the transmission electron microscopy (TEM), the nuclear magnetic resonance (NMR) and the Infrared (IR) spectroscopy. The magnetic measurements at room temperature, using a vibrating sample magnetometer (VSM), and the obtained magnetic parameters revealed that the investigated nanocomposites belong to a category of magnetically soft materials that find widespread applications in contemporary fine technologies. Optical absorption spectra were measured in the ultraviolet

A faunistic list of spider wasps (Pompilidae) collected from the western region of Saudi Arabia is presented. It comprises 29 species belonging to 18 genera in three subfamilies, of which 22 are newly recorded from Saudi Arabia. The previously unknown male of Agenioideus spiniprivus (Priesner) is discussed. This first part is followed by a list of the species name previously recorded from Saudi Arabia or which are expected to occur there.