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Shoukry, M. M., A. A. Al-Najjar, W. M. Hosny, A. E. Mahgoub, A. K. Abdelhadi, and P. A. Khalf-Alaa, "Thermodynamics of the Reactions of [Pd (Et4en)(H2O)2]2+with Ligands of Biological Significance: Deactivation of Based-Drug By the Sulfur-Containing Biomolecules", Journal of Sulpher Chem., vol. 32, pp. 563-573, 2011. AbstractCU-PDF.pdf

The reaction of [Pd(Et4en)(H2O)2]2+ (Et4en = N,N,N_,N_-tetraethylethylenediamine) with amino acids, peptides, dicarboxylic acids or DNA constituents was investigated at 37?C and 0.16M ionic strength. The stoichiometry and stability of the complexes formed were determined and the binding centers of the ligands were assigned. The concentration distribution diagrams of the complexes were evaluated. The equilibrium constants for the displacement of representative coordinated ligands such as inosine, glycine or methionine by mercaptoethylamine were calculated and the concentration distribution diagrams of the various species were evaluated.

El-Sherif, A. A., M. R. Shehata, M. M. Shoukry, and M. H. Barakat, "Thermodynamic Investigation and Mixed Ligand Complex Formation of 1,4-Bis-(3-Aminopropyl)- PiperazineandBiorelevant Ligands", Bioinorganic Chemistry and Applications, 2012.
A.Soliman, G., E. S.Taher, and M. A.Mahmoud, "Therapeutic Efficacy of", Turkiye Parazitol Derg, 2011. AbstractCU-PDF.pdf

Three commonly used Antihelmenthic drugs including Dormectin (0.2 mg/kg), Ivermectin (0.2 mg/kg) and Levamisole (7.5 mg/kg) were examined for their antihelmenthic efficacy against experimental Trichinella spiralis infection in rats. Methods: One hundred and twenty rats were orally infected with 500 T. spiralis larvae. Drugs were tested against adult worms at 4 < sup > th day, against migrating larvae at 10 < sup > th days and against encysted larvae at 35 < sup > th day post infection (dpi). Rats were sacrificed five days post treatment.

Dawood, H., "Theories of Interval Arithmetic Mathematical Foundations and Applications", LAP Lambert Academic Publishing, 2011. Abstract

(Book Description): Scientists are, all the time, in a struggle with uncertainty which is always a threat to a trustworthy scientific knowledge. A very simple and natural idea, to defeat uncertainty, is that of enclosing uncertain measured values in real closed intervals.

Tadros, W., M. Saadeldin, and S. A. Hassan, "Theoretical and Experimental Investigations of SolarHeating Systems at Specified Output Conditions of Hot Water", Journal of Energy and Power Engineering, 2011. Abstract

The theoretical analysis discussed in this work is a suitable mathematical tool by which theperformance of the proposed collector can be predicted. The obtained experimental results coincide withthe obtained theoretical data obtained from the devised computer program. Controlled output temperaturecan be obtained from the proposed system. The performance of the tested collector under the proposed intermittent flow conditions overcomes that of the conventional thermosyphone flow collector.

Kratz, K., S. A. Madbouly, W. Wagermaier, and A. Lendlein, "Temperature-Memory Polymer Networks with Crystallizable Controlling Units", Advanced Materials, vol. 23, pp. 4058-4062, 2011. CU-PDF.pdf
El-Ghani, M. A., M. Karam, F. A. El-Baky, and R. Ali, "Taxonomic Relationships In Veronica Sect", Phytologia Balcanica, vol. 17, issue 1, pp. 35-44, 2011. AbstractCU-PDF.pdf

There has been a great deal of controversy regarding the taxa and their taxonomic status of Veronica sect. Beccabunga in Egypt. The present study aimed at critical reappraisal of the taxonomy of Veronica sect. Beccabunga in Egypt by numerical and molecular approaches. Representative specimens were collected from their natural habitats and subjected to morphological description and RAPD amplification, using five random primers. Cluster analysis was applied to morphological and RAPD data separately.

Moubasher, H., A. M. M. El-Ghani, W. Kamel, M. Mansi, and M. El-Bous, "Taxonomic considerations among and within some Egyptian taxa of Capparis and related genera (Capparaceae) as revealed by RAPD fingerprinting", Collectanea Botanica, 2011. Abstract

Taxonomic considerations among and within some Egyptian taxa of Capparis and related genera (Capparaceae)as revealed by RAPD fingerprinting.- This investigation was carried out to assess the taxonomic relationships among eight taxa of the Egyptian members of Capparaceae based on random amplified polymorphic DNA markers, and to compare the results with those obtained from morphological studies.

Agouza, E. I. M., S. S. Eissa, E. M. M. Houseini, and D. E. - N. A. E. E. O. M. Hameed, "Taurine: A Novel Tumor Marker for Enhanced Detection of Breast Cancer Among Female Patients", Angiogenesis, vol. 14, issue 3, pp. 321-330, 2011. AbstractCU-PDF.pdf

Introduction: The antioxidant Taurine found to display antineoplastic effect through down regulation of angiogenesis and enhancement of tumor cell apoptosis. It has been found that progressive inhibition of apoptosis and induction of angiogenesis may contribute to tumor initiation, growth and metastasis in the pathogenesis of breast cancer. Aim of the study: To correlate taurine level with the levels of some bioomolecules operating in both angiogenesis (VEGF, CD31) and apoptosis (TNF-a and Caspas-3) which could help for breast cancer pronostication and to evaluate a possible role of serum taurine level as an early marker for breast cancer in Egyptian patients. Patients and methods: Four groups of a total 85 female candidates were studied in this work. The first group consists of 50 female patients at National Cancer Institute (NCI), Cairo University were diagnosed and undergoing surgery for breast carcinoma. In the second group 10 having benign breast lesions, were included. The third group consists of five cases, with positive family history. Twenty healthy females were also recruited as control. A preoperative blood sample were taken from each patient to measure serum level of VEGF; Taurine; CA15.3 and TNFa. Sample of fresh tumor and their corresponding safety margins were obtained from the first and second groups, for determination of caspase-3; histopathological examination and immunohistochemical assay of VEGF and CD31.

Alasaada, S., R.?nC. Soriguera, M. Abu-Madib, A. E. Behairyc, M. J. Jowersa, P. D.?ez Ba?nosd, A. P.?riz a, J. F. e, Xing-, and Q. Zhuf, "A TaqMan Real-time PCR-based Assay for the Identification of Fasciola Spp", Veterinary Parasitology, 2011.
Galmed, M. A., M. F. Aly, A. Smadi, and H. A. G. Azzam, "Taphonomic and Diagenetic Aspects of the Late Cretaceous Libycoceras Ismaeli (Zittel) From Northern Jordan", Arabian Journal of Geosciences, 2011. Abstract


Afify, A. E. - M. M. R., S. A. Fayed, E. A. Shalaby, and H. A. and El-Shemy, "Syzygium Cumini (pomposia) Active Principles Exhibit Potent Anticancer and Antioxidant Activities", African Journal of Pharmacy and Pharmacology, 2011. Abstract

The antioxidant and anticancer activities of Syzygium cumini fruit extracts were investigated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical-scavenging assay and viability of leukemia cancer cells (AML cell line) respectively. The successive extracts, hexane, chloroform, ether, ethyl acetate, ethanol and water were prepared and subjected to antioxidant and anticancer evaluation. The results showed that the ethanol extract had stronger antioxidant and anti- leukemia activities than the other ones. Spectroscopic methods data of active ingredients separated from ethanol extract indicated that S.cumini fruit extracts contained phenolic compounds, such as Kaempferol 7-O-methylether and sterols such as ?-Sitosterol responsible for their antioxidant and anticancer activities.

Abdel-Wahab, B. F., H. A. Mohamed, A. A. Farahat, and K. M. Dawood, "Synthetic Accesses to Azolylthiazoles", Heterocycles, 2011. Abstract

Published data over the last years on the methods of synthesis and biological applications of azolylthiazoles are reviewed here for the first time till 2011. The review was classified according to the type of azole ring linked to thiazole.

Metwally, N. H., and S. El-Taher, "Synthesis, Theoretical Study and Antimicrobial Activity of Novel Polysubstiuted Thiazoles", Heterocycles, 2011. Abstract

New 5-(9H-Fluoren-9-ylidene)- and 5-(1H-indan-1-ylidene)-2-thioxo-4-thiazolidinones 3a,b were synthesized Eco-friendly under microwave irradiation(MWI). These compounds undergo alkaline hydrolysis to afford thecorresponding thiol derivatives 4a,b, which cyclized into polysubstituted thiazoles 6a-h using arylazomalononitriles 5a-d as nucleophilic agents. Some selected products were tested for their antimicrobial activities. The equilibrium geometries of the studied compounds were calculated at the B3LYP/6-31G(d) level of the density functional theory (DFT). Conformational analysis has been carried out to determine the most stable conformers. The relative stability of the azo and hydrazo tautomers has been investigated. The HOMO-LUMO energy gap is used in rationalizing the reactivity of the studied compounds.

Zayed, M. A., G. G. Mohamed, and S. A. M. Abdullah, "Synthesis, Structure Investigation, Spectral Characteristics and Biologicalactivities of some Novel Azodyes", Spectrochimica Acta, 2011.
El-halim, H. A. F., M. M. Omar, and G. G. Mohamed, "Synthesis, Structural, Thermal Studies and Biological Activity of A Tridentate Schiff Base Ligand and their Transition Metal Complexes", Spectrochimica Acta, 2011. Abstract

Schiff base (L) ligand is prepared via condensation of pyridine-2,6-dicarboxaldehyde with 2-aminopyridine. The ligand and its metal complexes are characterized based on elemental analysis, mass, IR, solid re?ectance, magnetic moment, molar conductance, and thermal analyses (TG, DTG and DTA). The molar conductance reveals that all the metal

El-Ansary, A. L., H. M. Abdel-Fatah, and N. S. Abdel-Kader, "Synthesis, Spectral, Thermal and Magnetic Studies of Mn(II), Ni(II) and Cu(II) Complexes with Some Benzopyran-4-one Schiff bases", Spectrochim. Acta A, 2011. Abstract

The Schiff bases of N2O2 dibasic ligands, H2La and H2Lb are prepared by the condensation of ethylenediamine (a) and trimethylenediamine (b) with 6-formyl-7-hydroxy-5-methoxy-2-methylbenzopyran-4-one. Also tetra basic ligands, H4La and H4Lb are prepared by the condensation of aliphatic amines (a) and (b) with 6-formyl-5,7-dihydroxy-2-methylbenzopyran-4-one. New complexes of H4La and H4Lb with metal ions Mn(II), Ni(II) and Cu(II) are synthesized, in addition Mn(II) complexes with ligands H2La and H2Lb are also synthesized. Elemental and thermal analyses, infrared, ultraviolet-visible as well as conductivity and magnetic susceptibility measurements are used to elucidate the structure of the newly prepared metal complexes. The structures of copper (II) complexes are also assigned based upon ESR spectra study. All the complexes separated with the stoichiometric ratio (1:1) (M:L) except Mn-H4La and Mn-H4Lb with (2:1) (M:L) molar ratio. In metal chelates of the type 1:1 (M:L), the Schiff bases behave as a dinegative N2O2 tetradentate ligands. Moreover in 2:1 (M:L) complexes, the Schiff base molecules act as mono negative bidentate ligand and binuclear complex is then formed. The Schiff bases were assayed by the disc diffusion method for antibacterial activity against Staphylococcus aureus and Escherichia coli. The antifungal activity of the Schiff bases was also evaluated against the fungi Aspergillus flavus and Candida albicans.

Hassaneen, H. M., H. M. E. Hassaneen, and Y. S. M. R. M. Pagni, "Synthesis, Reactions and Antibacterial Activity of 3-Acetyl[1,2,4]triazolo-[3,4-a]isoquinoline Derivatives using Chitosan as Heterogeneous Catalyst under Microwave Irradiation", Z. Naturforsch., 2011. Abstract

3-Acetyl[1,2,4]triazolo[3,4-a]isoquinolines were prepared using chitosan as a catalyst. These compounds were used to prepare a novel series of enaminones 5, and their reactions with hydrazonoyl halides 1 and 11 gave triazoloisoquinolines 8 and 13, respectively, with a carbonylpyrazole side chain. Hydrazinolysis of 8 and 13 gave the pyrazolopyridazines 10 and pyrazolopyridazinones 14. Reaction of 5 with hydroximoyl halides 15 led to triazoloisoquinoline 16 with a carbonylisoxazole side chain. Antibacterial effects of compounds 8 and 10 were studied.

El-Sherif, A. A., M. R. Shehata, M. M. Shoukry, and M. H. Barakat, "Synthesis, Characterization, Equilibrium Study and Biological Activity of Cu (Ii),Ni(Ii) and Co(Ii) Complexes of Polydentate Schiff Base Ligand", SpectrochimicaActa Molecular and BiomolecularSpectroscopy, 2012.
El-Sherif, A. A., M. R. Shehata, M. M. Shoukry, and M. H. Barakat, "Synthesis, Characterization, Equilibrium Study and Biological Activity of Cu (Ii),Ni(Ii) and Co(Ii) Complexes of Polydentate Schiff Base Ligand", SpectrochimicaActa Molecular and BiomolecularSpectroscopy, 2012.
Elsabee, M. Z., E. A. Ali, S. M. Mokhtar, and M. Eweis, "Synthesis, Characterization Polymerization and Antibacterial Properties of Novel Thiophene Substituted Acrylamide", Reactive and Functional Polymers, 2011. Abstract

Ethyl 2-acrylamido-4,5,6,7-tetrahydrobenzo [b] thiophene-3-carboxylate (ETTCA) has been synthesized and its structure has been elucidated by elemental analysis and spectral tools. Free radical polymerization of (ETTCA) has been conducted in several solvents using azobisisobutyronitrile (AIBN) as an initiator.

Dawood, K. M., H. A. Mohamed, H. Abdel-Gawad, and F. A. Badria, "Synthesis, anti-HSV-1, and cytotoxic activities of some Newpyrazole- and Isoxazole-Based Heterocycles", Med. Chem. Res., 2011.