Identification, Phylogenetic Analysis and Expression Profile of an Anionic Insect Defensin Gene, with Antibacterial Activity, from Bacterial Challenged Cotton Leafworm, Spodoptera Littoralis

Citation:
Seufi, A. E. M., E. E. Hafez, and F. H. Galal, "Identification, Phylogenetic Analysis and Expression Profile of an Anionic Insect Defensin Gene, with Antibacterial Activity, from Bacterial Challenged Cotton Leafworm, Spodoptera Littoralis", BMC Molecular Biology, 2011.

Abstract:

Background: Defensins are a well known family of cationic antibacterial peptides (AMPs) isolated from fungi, plants, insects, mussels, birds, and various mammals. They are predominantly active against gram (+) bacteria, and a few of them are also active against gram (-) bacteria and fungi. All insect defensins belonging to the invertebrate class have a consensus motif, C-X5-16-C-X3-C-X9-10-C-X4-7-CX1-C. Only seven AMPs have already been found in different lepidopteran species. No report was published on the isolation of defensin from the Egyptian cotton leafworm, Spodoptera littoralis.

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