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Abdel-Gawad, S. A., and M. A. Alamri, "Fabrication of Sensitive Membrane Electrodes and their Application in Electrochemical Quantification of Ibandronate in Dosage Form", ELECTROANALYSIS, vol. 33, pp. 249-255, 2020.
Moustapha, M. E., and S. A. Abdel-Gawad, "Solid phase extraction and LC-MS/MS quantification of ibandronate in human plasma", Tropical Journal of Pharmaceutical Research , vol. 19, issue 6, pp. 1295-1302, 2020.
A.Abdel-Gawad, S., and M. A. Alamri, "Solid-phase extraction and validated spectrofluorimetric quantification of pamidronate in human plasma ", Tropical Journal of Pharmaceutical Research, vol. 19, issue 12, pp. 2651-2657 , 2020.
A.Abdel-Gawad, S., A. Alabbas, P. Alam, and M. A. Alamri, "Spectrophotometric and spectrodensitometric quantification of a new antiviral combination", JPC – Journal of Planar Chromatography – Modern TLC, vol. 33, issue 1, pp. 79-87, 2020.
A.Abdel-Gawad, S., and S. M. Alqahtani, "Ultra-performance liquid chromatography–tandem mass spectrometric determination of ramipril in human plasma ", Tropical Journal of Pharmaceutical Research, vol. 19, issue 4, pp. 851-857, 2020.
A.Abdel-Gawad, S., A. K. A. Suwailem, and S. S. AlShowiman, Validated High Performance Liquid Chromatographic Quantification of Pamidronate in Bulk and Dosage Form, , 2020.
DONIA, A. - R. M. A., S. A. Abdel-Gawad, A. A. Al-Kahtani, F. IMAM, N. F. Hassan, and M. H. GESSI, "Chromatographic Stability Indicating Quantification of Ramipril in Bulk and Dosage Forms", Latin American Journal of Pharmacy, vol. 37, issue 8, pp. 1651-1658, 2018. latin_american_journal_paper.pdf
El-Gamal, R. M., S. A. Abdel-Gawad, F. F. Belal, and M. E. Moustapha, "Selective and sensitive spectrofluorimetric quantification of velpatasvir in presence of sofosbuvir. Application to their co-formulated tablet", RSC Advances, vol. 8, issue 57, pp. 32909-32915, 2018. paper_fluori_rsc.pdf
Ibrahim, H. K., M. M. Abdel-Moety, S. A. Abdel-Gawad, M. A. Al-Ghobashy, and M. A. Kawy, "Validated electrochemical and chromatographic quantifications of some antibiotic residues in pharmaceutical industrial waste water.", Environmental science and pollution research international, vol. 24, issue 8, pp. 7023-7034, 2017 Mar. Abstract

Realistic implementation of ion selective electrodes (ISEs) into environmental monitoring programs has always been a challenging task. This could be largely attributed to difficulties in validation of ISE assay results. In this study, the electrochemical response of amoxicillin trihydrate (AMX), ciprofloxacin hydrochloride (CPLX), trimethoprim (TMP), and norfloxacin (NFLX) was studied by the fabrication of sensitive membrane electrodes belonging to two types of ISEs, which are polyvinyl chloride (PVC) membrane electrodes and glassy carbon (GC) electrodes. Linear response for the membrane electrodes was in the concentration range of 10-10 mol/L. For the PVC membrane electrodes, Nernstian slopes of 55.1, 56.5, 56.5, and 54.0 mV/decade were achieved over a pH 4-8 for AMX, CPLX, and NFLX, respectively, and pH 3-6 for TMP. On the other hand, for GC electrodes, Nernstian slopes of 59.1, 58.2, 57.0, and 58.2 mV/decade were achieved over pH 4-8 for AMX, CPLX, and NFLX, respectively, and pH 3-6 for TMP. In addition to assay validation to international industry standards, the fabricated electrodes were also cross-validated relative to conventional separation techniques; high performance liquid chromatography (HPLC), and thin layer chromatography (TLC)-densitometry. The HPLC assay was applied in concentration range of 0.5-10.0 μg/mL, for all target analytes. The TLC-densitometry was adopted over a concentration range of 0.3-1.0 μg/band, for AMX, and 0.1-0.9 μg/band, for CPLX, NFLX, and TMP. The proposed techniques were successfully applied for quantification of the selected drugs either in pure form or waste water samples obtained from pharmaceutical plants. The actual waste water samples were subjected to solid phase extraction (SPE) for pretreatment prior to the application of chromatographic techniques (HPLC and TLC-densitometry). On the other hand, the fabricated electrodes were successfully applied for quantification of the antibiotic residues in actual waste water samples without any pretreatment. This finding assures the suitability of the fabricated ISEs for environmental analysis.