Publications

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2021
Ashoub, A. H., D. H. Abdel-Naby, M. M. Safar, M. A. El-Ghazaly, and S. A. Kenawy, "Ameliorative effect of fractionated low-dose gamma radiation in combination with ellagic acid on nicotine-induced hormonal changes and testicular toxicity in rats ", Environ Sci Pollut Res Int , vol. 28, issue 18, pp. 23287-23300, 2021. aliaa_nicotine.pdf
Mahmoud, M. A. A., D. O. Saleh, M. M. Safar, A. M. Agha, and M. M. Khattab, "Chloroquine ameliorates bone loss induced by D-galactose in male rats via inhibition of ERK associated osteoclastogenesis and antioxidant effect ", Toxicology Reports , vol. 8, pp. 366–375, 2021.
Aglan, H. S., M. M. Safar, A. A. - M. Ain-Shoka, A. M. Kandil, S. Gebremedhn, D. Salilew-Wondim, K. Schellander, and D. Tesfaye, "Developmental toxicity of lead in rats after gestational exposure and the protective role of taurine", J Biochem Mol Toxicol, vol. 35, issue 8, pp. e22816, 2021. hoda_lead.pdf
Safar, M. M., N. F. Abdelkader, E. Ramadan, M. A. Kortam, and A. F. Mohamed, "Novel mechanistic insights towards the repositioning of alogliptin in Parkinson's disease", Life Sciences, vol. 287, pp. 120132, 2021. Alogliptin.pdf
El-Maadawy, W. H., S. S. H. el-Din, S. M. Ezzat, O. A. Hammam, M. M. Safar, S. Saleh, and N. M. El-Lakkany, "Rutin Ameliorates Hepatic Fibrosis via Targeting Hepatic Stellate Cells’ Activation, Proliferation and Apoptosis ", Journal of Herbs, Spices & Medicinal Plants , vol. 27, issue 3, pp. 322–341, 2021. rutin_walaa_elmadawy.pdf
2020
Gowifel, A. M. H., M. G. Khalil, S. A. Nada, Sanaa A. Kenawy, K. A. Ahmed, M. M. Salama, and M. M. Safar, "Combination of pomegranate extract and curcumin ameliorates thioacetamide-induced liver fibrosis in rats: Impact on TGF-β/Smad3 and NF-κB signaling pathways", Toxicology Mechanisms and Methods, vol. 30, issue 8, pp. 620-633, 2020.
Hessin, A. F., R. R. Hegazy, M. M. Safar, N. Z. Yassin, and S. A. - B. Kenawy, "Construction and Assessment of a Novel Vaccine Targeting Hepatocellular Carcinoma", Egyptian Journal of Chemistry, vol. 63, issue 3, pp. 867-884, 2020. vaccine.pdf
Mohamed, M. A. E., R. F. Abdel-Rahman, S. S. Mahmoud, M. M. Khattab, and M. M. Safar, "Metformin and trimetazidine ameliorate diabetes-induced cognitive impediment in status epileptic rats", Epilepsy & Behavior, vol. 104, pp. 106893, 2020. Trimetazide.pdf
Nasr, N. A. E. - M. E., D. O. Saleh, S. S. Mahmoud, S. M. Nofal, R. M. Abdelsalam, M. M. Safar, and H. S. El-Abhar, "Olmesartan attenuates type 2 diabetes-associated liver injury: Cross-talk of AGE/RAGE/JNK, STAT3/SCOS3 and RAS signaling pathways", European Journal of Pharmacology, vol. 874, pp. 173010, 2020. Olmesartan.pdf
Safar, M. M., N. N. Shahin, A. F. Mohamed, and N. F. Abdelkader, "Suppression of BACE1 and amyloidogenic/RAGE axis by sitagliptin ameliorates PTZ kindling-induced cognitive deficits in rats", Chemico-Biological Interactions, vol. 328, pp. 109144, 2020. Sitagliptin.pdf
Khalifa, M., M. M. Safar, R. M. Abdelsalam2, and H. F. Zaki, "Telmisartan Protects Against Aluminum-Induced Alzheimer-like Pathological Changes in Rats", Neurotoxicity Research, vol. 37, issue 2, pp. 275-285, 2020. Telmisartan.pdf
2019
Oraby, M. A., M. F. El-Yamany, M. M. Safar, N. A. G. L. A. A. ASSAF, and H. A. Ghoneim, "Amelioration of Early Markers of Diabetic Nephropathy by Linagliptin in Fructose-Streptozotocin-Induced Type 2 Diabetic Rats ", Nephron, vol. 141, issue 4, pp. 273-286. , 2019. linagliptin_mamdouh.pdf
El-Lakkany, N. M., W. H. El-Maadawy, S. S. H. el-Din, S. Saleh, M. M.Safar, S. M. Ezzat, S. H. Mohamed, S. S. Botros, Z. Demerdash, and O. A. Hammam, Antifibrotic effects of gallic acid on hepatic stellate cells: In vitro and in vivo mechanistic study, , 2019. gallic_acid_walaa.pdf
Oraby, M. A., M. F. El-Yamany, M. M. Safar, N. A. G. L. A. A. ASSAF, and H. A. Ghoneim, "Dapagliflozin Attenuates Early Markers of Diabetic Nephropathy in Fructose-Streptozotocin-Induced Diabetes in Rats ", Biomedicine & Pharmacotherapy, vol. 109, pp. 910–920. , 2019.
AL-Shafeiy, H. M., B. M. M. Ibrahim, M. M. Safar, S. E. - M. A. Shenawy, N. A. Z. Yassin, and S. A. Kenawy, Fluconazole, a Fungal Cytochrome P450 Enzyme Inhibitor: The Potential Role in Augmenting Hepatotoxicity and Hyperinsulinemia Induced by Dexamethasone in Rats, , 2019. fluconazole.pdf
Alawdi, S. H., H. Eidi, M. M. Safar, and M. A. Abdel-Wahhab, Loading Amlodipine on Diamond Nanoparticles: A Novel Drug Delivery System, , 2019. loading_amlodipine.pdf
Ibrahim, A. A., H. M. Karam, E. A. Shaaban, M. M. Safar, and M. F. El-Yamany, "MitoQ ameliorates testicular damage induced by gamma irradiation in rats: Modulation of mitochondrial apoptosis and steroidogenesis ", Life Sciences, vol. 232, issue 9, pp. 116655-, 2019. mito_q.pdf
2018
Zaki, O. S., M. M. Safar, A. A. Ain-Shoka, and L. A. Rashed, "Bone Marrow Mesenchymal Stem Cells Combat Lipopolysaccharide-Induced Sepsis in Rats via Amendment of P38-MAPK Signaling Cascade", Inflammation, vol. 41, issue 2, pp. 541-554, 2018. omnia_stem_cells.pdf
Lotfy, D. M., M. M. Safar, S. H. Mohamed, and S. A. Kenawy, "Effect of valproic acid alone or combined with low dose gamma irradiation in modulating PTZ-induced convulsions in rats involving AKT/m-TOR pathway.", Life Sciences, vol. 212, issue 1, pp. 261-266, 2018. dina_irradiation_epilepsy.pdf
Zaki, O. S., M. M. Safar, A. A. Ain-Shoka, and L. A. Rashed, "A Novel Role of a Chemotherapeutic Agent in a Rat Model of Endotoxemia: Modulation of the STAT-3 Signaling Pathway ", Inflammation, vol. 41, issue 1, pp. 20-32, 2018. imatinib.pdf
Ayoub, B. M., S. Mowaka, M. M. Safar, N. Ashoush, M. G. Arafa, H. E. Michel, M. M. Tadros, M. M. Elmazar, and S. A. Mousa, "Repositioning of Omarigliptin as a once-weekly intranasal Anti-parkinsonian Agent", Sci Rep, vol. 8, issue 1, pp. 8959-8972, 2018. omarigliptin.pdf
2017
Alawdi, S. H., E. S. El-Denshary, M. M. Safar, H. Eidi, and M. - O. David, "Neuroprotective Effect of Nanodiamond in Alzheimer’s Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling", Molecular Neurobiology, vol. 54, issue 3, pp. 1906–1918, 2017. nanodiamonds.pdf
M.El-Lakkany, N., W. H. El-Maadawy, S. S. H. el-Din, O. A.Hammam, S. H. Mohamed, S. M. Ezzat, M. M. Safar, and S. Saleh, "Rosmarinic acid attenuates hepatic fibrogenesis via suppression of hepatic stellate cell activation/proliferation and induction of apoptosis.", Asian Pacific Journal of Tropical Medicine, vol. 10, issue 5, pp. 444-453, 2017. rosmarinic_acid.pdf
Mohamed, A. F., M. M. Safar, H. F. Zaki, and H. M. Sayed, "Telluric Acid Ameliorates Endotoxemic Kidney Injury in Mice: Involvement of TLR4, Nrf2, and PI3K/Akt Signaling Pathways", Inflammation, vol. 40, issue 5, pp. 1742–1752, 2017. telluric.pdf