Publications

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2021
Amin, K. M., G. H. Hegazy, R. F. George, N. R. Ibrahim, and N. M. Mohamed, "Design, synthesis, and pharmacological characterization of some 2‐substituted‐3‐phenyl‐quinazolin‐4(3H)‐one derivatives as phosphodiesterase inhibitors", Archiv der Pharmazie, vol. 354, pp. e2100051, 2021.
Bokhita, R. M., S. S. Panda, A. S. Girgis, H. H. Honkanadavar, T. S. Ibrahim, R. F. George, M. O. N. A. T. KASHEF, W. A. L. I. D. FAYAD, R. Sakhuja, E. H. Abdel-Aal, et al., "Flouroquinolone-3-carboxamide amino acid conjugates: Synthesis, antibacterial properties and molecular modeling studies", Medicinal Chemistry, vol. 17, pp. 71-84, 2021.
Hassan, G. S., H. H. Georgey, E. Z. Mohammed, R. F. George, W. R. Mahmoud, and F. A. Omar, "Mechanistic selectivity investigation and 2D-QSAR study of some new antiproliferative pyrazoles and pyrazolopyridines as potential CDK2 inhibitors", European Journal of Medicinal Chemistry , vol. 218, pp. 113389, 2021.
Ewida, M. A., H. A. Ewida, M. S. Ahmed, H. A. Allam, R. I. Elbagary, R. F. George, H. H. Georgey, and H. I. El‐Subbagh, "Nanomolar potency of imidazo[2,1‐b]thiazole analogs as indoleamine 2,3‐dioxygenase inhibitors", Archiv der Pharmazie, vol. 354, pp. e2100202, 2021.
Mahdally, N. H., R. F. George, M. O. N. A. T. KASHEF, M. Al-Ghobashy, F. E. Murad, and A. S. Attia, "Staquorsin: A Novel Staphylococcus aureus Agr-Mediated Quorum Sensing Inhibitor Impairing Virulence in vivo Without Notable Resistance Development", Frontiers in Microbiology, vol. 12, pp. 700494, 2021.
Mohammed, E. Z., W. R. Mahmoud, R. F. George, G. S. Hassan, F. A. Omar, and H. H. Georgey, "Synthesis, in vitro anticancer activity and in silico studies of certain pyrazole-based derivatives as potential inhibitors of cyclin dependent kinases (CDKs)", Bioorganic Chemistry, vol. 116, pp. 105347, 2021.
2022
El-Aleam, R. A. H., A. M. Sayed, M. N. Taha, R. F. George, H. H. Georgey, and H. M. Abdel-Rahman, "Design and synthesis of novel benzimidazole derivatives as potential Pseudomonas aeruginosa anti-biofilm agents inhibiting LasR: Evidence from comprehensive molecular dynamics simulation and in vitro investigation", European Journal of Medicinal Chemistry, vol. 241, pp. 114629, 2022.
Farouk, A. K. B. A. W., H. A. Allam, E. Rashwan, R. F. George, and S. E. - S. Abbas, "Design and synthesis of some new 6-bromo-2-(pyridin-3-yl)-4-substituted quinazolines as multi tyrosine kinase inhibitors", Bioorganic Chemistry, vol. 128, pp. 106099, 2022.
Aziz, N. A. A. M., R. F. George, K. El-Adl, and W. R. Mahmoud, "Design, synthesis, in silico docking, ADMET and anticancer evaluations of thiazolidine-2,4-diones bearing heterocyclic rings as dual VEGFR-2/ EGFRT790M tyrosine kinase inhibitors", RSC Advances, vol. 12, pp. 12913–12931, 2022.
Abbas, S. E. - S., N. M. Abdel-Gawad, R. F. George, M. A. G. Elyazid, M. A. Zaater, and M. K. El-Ashrey, "Some 2-(4-bromophenoxymethyl)-6-iodo-3-substituted quinazolin-4(3H)ones: Synthesis, cytotoxic activity, EGFR inhibition and molecular docking", Journal of Molecular Structure , vol. 1269 , pp. 133851, 2022.
Said, M. F., R. F. George, A. Petreni, C. T. Supuran, and N. M. Mohamed, "Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 37, issue 1, pp. 701-717, 2022.
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