Publications

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George, R. F., N. Samir, I. M. Ayoub, E. S. M. Shalaby, N. Demitri, and M. Wink, "Synthesis, antiproliferative activity and 2D-QSAR study of some 8-alkyl-2,4-bisbenzylidene-3-nortropinones", Future Medicinal Chemistry, vol. 10, issue 24, pp. 2815–2833, 2018.
George, R. F., "Facile synthesis of simple 2-oxindole-based compounds with promising antiproliferative activity", Future Medicinal Chemistry, vol. 10, issue 3, pp. 269-282, 2018.
George, R. F., S. S. Panda, E. - S. M. Shalaby, A. M. Srour, A. I. S. Farag, and A. S. Girgis, "Synthesis and molecular modeling studies of indole-based antitumor agents", RSC Advances, vol. 6, pp. 45434-45451, 2016. rsc_adv._2016_6_45434.pdf
George, R. F., M. Kandeel, D. Y. El-Ansary, and A. E. M. Kerdawy, "Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking", Bioorganic Chemistry, vol. 99, pp. 103780, 2020.
George, R. F., N. S. M. Ismail, J. Stawinski, and A. S. Girgis, "Design, synthesis and QSAR studies of dispiroindole derivatives as new antiproliferative agents", European Journal of Medicinal Chemistry, vol. 68, pp. 339-351, 2013. eur._j._med._chem._68_339-351_2013.pdf
George, R. F., E. M. Samir, M. N. Abdelhamed, H. A. Abdel-Aziz, and S. E. S. Abbas, "Synthesis and anti-proliferative activity of some new quinoline based 4,5-dihydropyrazoles and their thiazole hybrids as EGFR inhibitors", Bioorganic Chemistry, vol. 83, pp. 186–197, 2019.
George, R. F., and D. O. Saleh, "Synthesis, vasorelaxant activity and 2D-QSAR study of some novel pyridazine derivatives", European Journal of Medicinal Chemistry, vol. 108, pp. 663-673, 2016. full_text_published_article.pdf
Ghanem, N. M., F. Farouk, R. F. George, S. E. S. Abbas, and O. M. El-Badry, "Design and synthesis of novel imidazo[4,5-b]pyridine based compounds as potent anticancer agents with CDK9 inhibitory activity", Bioorganic Chemistry, vol. 80, pp. 565–576, 2018.
Girgis, A. S., D. O. Saleh, R. F.George, A. M. Srour, G. G. Pillai, C. S. Panda, and A. R. Katritzky, "Synthesis, Bioassay, and QSAR Study of Bronchodilatory Active 4H-Pyrano[3,2-c]pyridine-3-carbonitriles", European Journal of Medicinal Chemistry, vol. 89, pp. 835-843, 2015. ejmc_89_835-843_2015.pdf
Girgis, A. S., A. F. Mabied, J. Stawinski, L. Hegazy, R. F. George, H. Farag, E. S. M. Shalaby, and A. I. S. Farag, "Synthesis and DFT studies of an antitumor active spiro-oxindole", New Journal of Chemistry, vol. 39, issue 10, pp. 8017-8027, 2015. new_journal_of_chemistry_2015_39_8017_-_8027.pdf
Girgis, A. S., H. Farag, N. S. M. Ismail, and R. F. George, "Synthesis, hypnotic properties and molecular modeling studiesof 1,2,7,9-tetraaza-spiro[4.5]dec-2-ene-6,8,10-triones", Eur.J.Med.Chem, vol. 46, pp. 4964-4969, 2011.
H
Hanna, M. M., N. M. Eid, R. F. George, and H. M. Safwat, "Synthesis of some tropane derivatives of anticipated activity on the reuptake of norepinephrine and /or serotonine", Bioorg.Med.Chem, vol. 15, pp. 7765, 2007.
Hanna, M. M., and R. F. George, "Facile Synthesis and Quantitative Structure–Activity Relationship Study of Antitumor Active 2-(4-Oxo-thiazolidin-2-ylidene)-3-oxo-propionitriles", Chem. Pharm. Bull, vol. 60, issue 9, pp. 1195–1206, 2012.
Hassan, G. S., H. H. Georgey, R. F. George, and E. R. Mohammed, "Construction of some cytotoxic agents with aurone and furoaurone scaffolds", Future Medicinal Chemistry, vol. 18, issue 1, pp. 27-52, 2018.
Hassan, G. S., H. H. Georgey, E. Z. Mohammed, R. F. George, W. R. Mahmoud, and F. A. Omar, "Mechanistic selectivity investigation and 2D-QSAR study of some new antiproliferative pyrazoles and pyrazolopyridines as potential CDK2 inhibitors", European Journal of Medicinal Chemistry , vol. 218, pp. 113389, 2021.
Hassan, G. S., H. H. Georgey, R. F. George, and E. R. Mohamed, "Aurones and furoaurones: Biological activities and synthesis", Bulletin of Faculty of Pharmacy, Cairo University, vol. 56, pp. 121-127, 2018.
I
Ismail, N. S. M., R. F. George, R. A. T. Serya, F. N. Baselious, M. El-Manawaty, E. S. M. Shalaby, and A. S. Girgis, "Rational design, synthesis and 2D-QSAR studies of antiproliferative tropane-based compounds", RSC Advances, vol. 6, pp. 101911-101923, 2016. rsc_advances_2016_6_101911_-_101923.pdf
M
Mabied, A. F., A. S. Girgis, E. - S. M. Shalaby, R. F. George, B. E. - D. M. El-Gendy, and F. N. Baselious, "Stereoselective Synthesis, Structural and Spectroscopic Study of 4,5,11- Triazatricyclo[6.2.1.0*2,6*]Undec-5-ene", J. Heterocyclic Chem., vol. 53, pp. 1074-1080, 2016.
Mahdally, N. H., R. F. George, M. O. N. A. T. KASHEF, M. Al-Ghobashy, F. E. Murad, and A. S. Attia, "Staquorsin: A Novel Staphylococcus aureus Agr-Mediated Quorum Sensing Inhibitor Impairing Virulence in vivo Without Notable Resistance Development", Frontiers in Microbiology, vol. 12, pp. 700494, 2021.
Marwa A Ibrahim, R. F. George, S. M. Abou-Seri, and S. M. El-Moghazy, "Synthesis of new phenolic compounds and biological evaluation as antiproliferative agents", Journal of Chemical Research, vol. 44, issue 3-4, pp. 181– 192, 2020.
Mohamed, A. R., A. E. M. Kerdawy, R. F. George, H. H. Georgey, and N. A. M. Gawad, "Design, synthesis and in silico insights of new 7,8-disubstituted-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione derivatives with potent anticancer and multi-kinase inhibitory activities", Bioorganic Chemistry, vol. 107, pp. 104569, 2021.
Mohamed, A. R., H. H. Georgey, R. F. George, W. I. El-Eraky, D. O. Saleh, and N. A. M. Gawad, "Identification of some novel xanthinebased derivatives with bronchodilator activity", Future Medicinal Chemistry, vol. 9, issue 15, pp. 1731-1747, 2017.
Mohammed, E. Z., W. R. Mahmoud, R. F. George, G. S. Hassan, F. A. Omar, and H. H. Georgey, "Synthesis, in vitro anticancer activity and in silico studies of certain pyrazole-based derivatives as potential inhibitors of cyclin dependent kinases (CDKs)", Bioorganic Chemistry, vol. 116, pp. 105347, 2021.
N
Naumov, R. N., S. S. Panda, A. S. Girgis, R. F. George, M. Farhat, and A. R. Katritzky, "Synthesis and QSAR study of novel anti-inflammatory active mesalazine–metronidazole conjugates", Bioorganic & Medicinal Chemistry Letters, vol. 25, issue 11, pp. 2314–2320, 2015. 57_bioorg._med._chem._lett._2015.pdf
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Oliferenko, P. V., A. A.Oliferenko, A. S. Girgis, D. O. Saleh, A. M. Srour, R. F.George, G. G. Pillai, C. S. Panda, D. C. Hall, and A. R. Katritzky, "Synthesis, Bioassay, and Molecular Field Topology Analysis of Diverse Vasodilatory Heterocycles.", Journal of Chemical Information and Modeling, vol. 54, pp. 1103-1116, 2014. j._chem._inform._modeling_54_11031116_2014.pdf