Publications

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2023
Mohareb, R. M., M. H. E. Helal, A. E. Mayhoub, and A. E. M. Abdallah, "MULTI-COMPONENT SYNTHESIS OF PYRAZOLO[1,5-a]QUINAZOLINE, THIAZOLE AND THIOPHENE DERIVATIVES AS CYTOTOXIC AGENTS", Bull Chem Society Of Ethyopia, vol. 37, pp. 1521-1538, 2023. bull_chem_soc_ethiopia_amany_2_2023.pdf
Abdallah, A. E. M., R. M. Mohareb, M. H. E. Helal, and M. A. M. Elkader, "Novel 5,6,7,8-tetrahydrobenzo[b]pyran Derivatives: Synthesis and Anticancer Activity", Acta Chim. Slov. , vol. 70, pp. 261-273, 2023. acta_chim_slov_2023_amira.pdf
2022
Rafat M Mohareb, Nadia Y Megally Abdou, R. I. E. S. A. M., "Anti-proliferative, c-Met Inhibitions, and PAINS Evaluations of New Thiophene, Thiazole, Coumarin, Pyran, and Pyridine Derivatives", Anti-Cancer Agents in Med Chem, vol. 22, pp. 2125-2141, 2022.
and Mohareb, N. M. A. R. M. Y., "Antiproliferative and Antiprostate Cancer Activities of Heterocyclic Compounds Derived from Cyclohexane-1,4-dione", Acta Chim. Slov. , vol. 69, pp. 700-713, 2022.
Rafat Milad Mohareb, Noha M Asaad Bagato, I. T. R., "Design, Synthesis, Molecular Docking, and Biological Studies of New Heterocyclic Compounds Derived from β-Diketones as Novel EGFR and Pim-1 Inhibitors Endowed with AntitumorActivity", Anti-cancer Agents in Med Chem, vol. 22, pp. 2558-2576, 2022.
Heba Hafez, Rafat M. Mohareb, S. S. A. M. E. E. H. A. M. A. F. H., "Molecular Mechanisms Underlying the Anti-Breast Cancer Stem Cell Activity of Pterocladia capillacea and Corallina officinalis Polysaccharides", Anti-Cancer Agents in Med Chem, vol. 22, pp. 1213-1225, 2022.
2021
Mohareb, R. M., R. A. Ibrahim, and E. El-wan, "Multicomponent Reactions of Cyclohexan-1,3-diketones to Produce Fused Pyran Derivatives with Antiproliferative Activities and Tyrosine Kinases and Pim-1 Kinase Inhibitions. ", Acta Chimica Slovania, vol. 68, pp. 51-64, 2021.
Mohareb, R. M., Y. R. Milad, and R. A. El-Ansary, "New Approaches for the Synthesis of Fused Thiophene, Pyrazole, Pyran and Pyridine Derivatives with Anti-Proliferative Together with c-Met Kinase and Prostate Cancer Cell Inhibition", Anticancer Agentsin Med Chem, vol. 21, pp. 1751-1766, 2021.
Mohareb, R. M., A. E. M. Abdallah, M. H. E. Helal1, and G. J. Mofeed, "Synthesis and Anticancer Evaluations of Novel Thiazole Derivatives Derived from 4-Phenylthiazol-2-amine", Acta Chim. Slov. , vol. 68, pp. 604-616, 2021.
2020
Mohareb, R. M., N. Y. Megalley, and W. N. Aldarkazali, "Heterocyclization of 2-Arylidenecyclohexan-1,3-dion: Synthesis of Thiophene, Thiazole and Isoxazole Derivatives with Potential Antitumor Activities", Amti-camcer Agent in Medicinal Chemistry, vol. 20, pp. 335-345, 2020.
Mohareb, R. M., F. M. Manhi, and A.; Abdelwahab, "Synthesis of Heterocyclic compounds Derived from Dimedone and their Antitumor and Tyrosine Kinae Inhibitions", Acta Chimica Slov. , vol. 67, pp. 83-95, 2020. acta_chemic_slov_-amal__2020.pdf
2018
Mohareb, R. M., A. E. M. Abdallah, and A. A. Mohamed, "Synthesis of Novel Thiophene, Thiazole and Coumarin Derivatives Based on Benzimidazole Nucleus and their Cytotoxicity and Toxicity Evaluations.", Chem Pharm Bull, vol. 66, pp. 309-318, 2018.
2017
Mohareb, R. M., F.Al-Omran, M. A. Abd El Aziz, and R. A. Ibrahim, "Anti-inflammatory and Anti-ulcer Activities of New Fused Thiazole Derivatives Derived from 2-(2-Oxo-2H-chromen-3-yl)thiazol-4(5H)-one", Acta Chim. Slov., vol. 64, pp. 349–364, 2017.
Mohareb, R. M., and R. A. Ibrahim, "Design, cytotoxicity and toxicity of new thiophene and thieno[2,3-b] pyridine derivatives", Med Chem Res , vol. 26, pp. 587–602, 2017.
Yahya, S. M. M., G. A. Elmegeed, M. S. Mohamed, R. M. Mohareb, M. M. Abd-Elhalim, and G. H. Elsayed, "The Effect of Newly Synthesized Heterosteroids on miRNA34a, 98, and 214 Expression Levels in MCF-7 Breast Cancer Cells", Ind J Clin Biochem , pp. 1-6, 2017.
Abdallah, A. M., R. M. Mohareb, E. M. Khalil, and M. A. M. Elshamy, "Synthesis of Novel Heterocyclic Compounds Incorporate 4,5,6,7-Tetrahydrobenzo[b]thiophene Together with Their Cytotoxic Evaluations", Chem. Pharm. Bull. , vol. 65, pp. 469–477, 2017.
Mohareb, R. M., N. S. Abbas, and A. A. Mohamed, "Synthesis of tetrahydropyrazolo-quinazoline and tetrahydropyrazolo-pyrimidocarbazole derivatives as potential anti-prostate cancer agents and Pim-1 kinase inhibitors", Med Chem Research , vol. 26, pp. 1073–1088, 2017.
Mohareb, R. M., N. Y. M. Abdo, and F. O. Al-Farouk, "Synthesis, Cytotoxic and Anti-proliferative Activity of Novel Thiophene, Thieno[2,3-b]pyridine and Pyran Derivatives Derived from 4,5,6,7-tetrahydrobenzo[b]thiophene Derivative", Acta Chim. Slov. , vol. 64, pp. 117–128, 2017.
2016
Mohareb, R. M., H. M. Hassaneen, and N. A. M. Ahmed, " New Approaches for the Synthesis of Thiophenes, Thiazole, Pyran Derivatives, and their Antitumor Evaluation", Jacobs Journal of Organic Chemistry, vol. 1(1), pp. 004, 2016.
Mohareb, R. M., N. Y. M. Abdo, and A. A. Mohamed, "Cytotoxicity and Anti-proliferative Properties of Heterocyclic Compounds Derived from Progesterone", Anticancer Agent in Med Chemistry , vol. 16(8), pp. 1043 – 1054, 2016.
Elmegeed, G. A., S. M. M. Yahya, S. M. M. Yahya, M. M. Abd-Elhalim, M. S. Mohamed, R. M. Mohareb, and G. H. Elsayed, "Evaluation of heterocyclic steroids and curcumin derivatives as anti-breast cancer agents: Studying the effect on apoptosis in MCF-7 breast cancer cells", Steroids, vol. 115, pp. 80-89, 2016.
El-Sayed, N. N. E., M. A. Abd El Aziz, W. W. Wardakhan, and R. M. Mohareb, "The Knoevenagel reaction of cyanoacetylhydrazine with pregnenolone: Synthesis of thiophene, thieno[2,3-d]pyrimidine, 1,2,4-triazole, pyran and pyridine derivatives with anti-inflammatory and anti-ulcer activities", Steroids, vol. 117, pp. 98-111, 2016.
Mohareb, R. M., A. M. Abdelazim, and A. Abdallah, "New Approaches for the Synthesis, Cytotoxicity and Toxicity of Heterocyclic Compounds Derived from 2-Cyanomethylbenzo[c]imidazole", Acta Chem Slov, vol. 63(2), pp. 227-40., 2016.
Mohareb, R. M., A. E. M. Abdallah, M. H. E. Helal, and S. M. H. Shaloof, "Synthesis and Structure Elucidation of Some Novel Thiophene and Benzothiophene Derivatives as Cytotoxic Agents", Acta Pharmaceutica, vol. 66, pp. 53-68, 2016.
Mohareb, R. M., and E. Elwan, "Synthesis of Pyran, Pyridine, Thiophene, Pyrimidine and Thiazole Derivatives with Antitumor Activities", Jacobs Journal of Organic Chemistry, vol. 1(1) , pp. 001, 2016.
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