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Alosaimi, M. F., H. Shendi, A. Beano, K. Stafstrom, R. E. Hawary, S. Meshaal, N. Galal, S. - Y. Pai, A. El-Marsafy, R. S. Geha, et al., "T cell mitochondrial dysfunction and lymphopenia in DOCK2-deficient patients", The journal of allergy and clinical immunology, vol. 144, issue 1, pp. 306-309, 2019.
Amin, D. G., "T cell receptor Zeta chain (TCRζ) expression in patients with idiopathic thrombocytopenic purpura", Bulletin of Egyptian society for physiological sciences, vol. 32, issue 1, 2012.
Ibrahim, S. A., S. F. Abdelwahab, M. M. Mohamed, A. M. Osman, E. Fathy, K. S. Al-Badry, N. Al-Kady, G. E. Esmat, and M. M. Al-Sherbiny, "T cells are depleted in HCV-Induced hepatocellular carcinoma patients: possible role of apoptosis and p53", Egypt J Immunol, vol. 13, pp. 11-22, 2006.
Ibrahim, S. A., S. F. Abdelwahab, M. M. Mohamed, A. M. Osman, E. Fathy, K. S. Al-Badry, N. Al-Kady, G. Esmat, and M. M. Al-Sherbiny, "T cells are depleted in HCV-induced hepatocellular carcinoma patients: possible role of apoptosis and p53", RETROVIROLOGY, vol. 3, no. 1}, Meeting Abstract = {S32, 2006. Abstract
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SA, I., A. SF, M. MM,, Jouini R, and et al, "T cells are depleted in HCV-Induced hepatocellular carcinoma patients: possible role of apoptosis and p53.", Egypt J Immunol. , vol. 13(2):11-22., 2006.
Sakr, A. A., M. F. Ghaly, and M. F. Ali, "T HE RELATIONSHIP BETWEEN SALTS AND GROWTH OF STREPTOMYCES COLONIES ISOLATED FROM MURAL PAINTINGS IN ANCIENT EGYPTIAN TOMBS", Conservation Science in Cultural Heritage, vol. 13, issue 2013, pp. 313 - 330, 2013.
Sewelam, N. I., H. Al-Wakeel, Z. Elsaadany, R. Magdy, and N. Fouad, "T helper 1/T helper 2-associated chemokine and chemokine receptor expression in immune thrombocytopenia", Egyptian Journal of Haematology, vol. 43, issue 3, pp. 119-124, 2018.
Sewelam, N. I., H. Al-Wakeel, E. Z. Saadany, and M. R. N. Fouad, "T helper 1/T helper 2-associated chemokine and chemokine receptor expression in immune thrombocytopenia", The Egyptian Journal of Haematology , vol. 43, issue 3, pp. 119, 2018.
HEGAZY, R. A., M. M. Fawzy, H. I. GAWDAT, N. E. S. R. I. N. SAMIR, and L. A. Rashed, "T helper 17 and Tregs: a novel proposed mechanism for NB-UVB in vitiligo.", Experimental dermatology, vol. 23, issue 4, pp. 283-6, 2014 Apr. Abstract

Narrowband ultraviolet (NB-UV)B is accepted as corner stone therapy for vitiligo. Its influence on the expression of IL-17, IL- 22 and FoxP3 as markers for the Th17 and Tregs lineages has not been studied before in the context of non-segmental vitiligo (NSV). The study included 20 active NSV patients who received 36 NB-UVB sessions and 20 controls. Clinical evaluation Vitiligo Area Scoring Index (VASI) and determination of tissue expression of IL-17, IL-22 and FoxP3 by qRT-PCR (lesional, perilesional) were carried out before and after therapy. Baseline levels of IL-17 and IL-22 were significantly higher in patients, whereas FoxP3 was significantly lower. After therapy, IL-17 and IL-22 significantly dropped, whereas FoxP3 significantly increased (lesional, perilesional). Baseline and post-treatment VASI showed significant positive correlations with IL-17 and IL-22 and significant negative correlation with FoxP3 expression. Restoration of the balance between Th17 and Tregs might represent a novel pathway for the improvement that NB-UVB exerts in vitiligo patients.

HEGAZY, R. A., M. M. Fawzy, H. I. GAWDAT, N. E. S. R. I. N. SAMIR, and L. A. Rashed, "T helper 17 and Tregs: a novel proposed mechanism for NB-UVB in vitiligo.", Experimental dermatology, vol. 23, issue 4, pp. 283-6, 2014. Abstract

Narrowband ultraviolet (NB-UV)B is accepted as corner stone therapy for vitiligo. Its influence on the expression of IL-17, IL- 22 and FoxP3 as markers for the Th17 and Tregs lineages has not been studied before in the context of non-segmental vitiligo (NSV). The study included 20 active NSV patients who received 36 NB-UVB sessions and 20 controls. Clinical evaluation Vitiligo Area Scoring Index (VASI) and determination of tissue expression of IL-17, IL-22 and FoxP3 by qRT-PCR (lesional, perilesional) were carried out before and after therapy. Baseline levels of IL-17 and IL-22 were significantly higher in patients, whereas FoxP3 was significantly lower. After therapy, IL-17 and IL-22 significantly dropped, whereas FoxP3 significantly increased (lesional, perilesional). Baseline and post-treatment VASI showed significant positive correlations with IL-17 and IL-22 and significant negative correlation with FoxP3 expression. Restoration of the balance between Th17 and Tregs might represent a novel pathway for the improvement that NB-UVB exerts in vitiligo patients.

ElEla, A. M., H. M. Rasheed, R. A. Hegazy, M. M. Fawzy, and L. Rashed, "T helper-17 and T regulatory cells in the complexity of vitiligo?. A case-controlled study on eighty-four non-segmental vitiligo patients", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 132: NATURE PUBLISHING GROUP 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA, pp. S16–S16, 2012. Abstract
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, "T HELPER-17 CELLS AND T REGULATORY CELLS IN VITILIGO", INTERNATIONAL JOURNAL of ACADEMIC RESEARCH, vol. 5, issue 6, pp. 273-278, 2013.
Hosni, H. A., and K. Ibrahim, "T of Egypt by their characterhe identification of grasses of the northwestern coastal region of Egypt by", Taeckholmia, vol. 24, issue 1, pp. 77-89, 2004.
Aisha A. Hagag1, H. A. Alnahas, A. F. Ismail1, and H. I. Hamed, "T –lymphocytes and cortisol response to resistance training in diabetics", bioscience research, vol. 16, issue 2, pp. 1223-1231, 2019.
Aisha A. Hagag1, H. A. Alnahas, A. F. Ismail1, and H. I. Hamed, "T –lymphocytes and cortisol response to resistance training in diabetics", bioscience research, vol. 16, issue 2, pp. 1223-1231, 2019.
Abbas, O. M., N. A. Omar, and Z. K. Hassan, "T(14;18) is not associated with mixed cryoglobulinemia or with clonal B cell expansion in egyptian patients with hepatitis C virus infection.", Journal of the Egyptian National Cancer Institute, vol. 20, issue 2, pp. 149-57, 2008. Abstract

BACKGROUND/AIM: The mechanisms of B-cell lymphoproliferative disorders in chronic hepatitis C virus (HCV) infection are unclear. An increased prevalence of circulating monoclonal B-cells and t(14;18) has been reported. Geographic heterogeneity of prevalence of t(14;18) has been shown to exist. We investigated the prevalence of t(14;18) and B-cell clonality as possible mechanisms of lymphomagenesis in chronic HCV patients, in whom cryoglobulinemia status was previously detected.

METHODS: A cohort of 111 patients was studied, including 87 patients with chronic HCV disease (18 cryoglobulinemic and 69 non- cryoglobulinemic); 24 HCV-negative, cryoglobulin negative patients with other nonimmune chronic liver diseases were enrolled as controls. The t(14;18) and IgH rearrangement (as a marker of B-cell clonality) were detected by the polymerase chain reaction.

RESULTS: t(14;18) was detected in 27.6% of HCV patients and in none of the controls. Detection rates were comparable in both cryoglobulin-positive and negative groups (22.2% and 29% , respectively), p=0.769. IgH rearrangement was detected in 39.1% of HCV patients and in none of the controls. The cryoglobulin-positive group showed significantly higher prevalence of IgH rearrangement compared to the cryoglobulin-negative group (61.1% and 33.3% , respectively), p=0.03, OR=3.13 and 95% CI=1.07-9.17. t(14;18) and monoclonal IgH rearrangement detection rates were not associated with each other, p=0.467.

CONCLUSIONS: t(14;18) is uncommon in HCV-mixed cryogoblulinemia Egyptian patients; it does not seem to play a role in HCV-associated MC and lymphomagenesis in our geographical area. HCV may play a role in mixed cryogoblulinemia and lymphomagenesis, probably by inducing clonal B-cell expansions.

Abdel-Sattar, E., "T-Cadinol and poliumoside from Teucrium yemense", Saudi Pharmaceutical Journal, vol. 3, pp. 188–191, 1995. Abstract
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Alosaimi, M. F., H. Shendi, A. Beano, K. Stafstrom, R. E. Hawary, S. Meshaal, N. Galal, ung-Yun Pai, A. El-Marsafy, and R. S. Geha, "T-cell mitochondrial dysfunction and lymphopenia in DOCK2-deficient patients.", Journal of Allergy and Clinical Immunology, vol. 144, issue 1, pp. 306–309.e2, 2019.
Shamloul, R., R. Beharry, T. Hale, J. Heaton, and M. Adams, "T01-O-16 Restoration of female genital vasocongestive arousal responses in young and aged rats", Sexologies, vol. 17: Elsevier, pp. S55, 2008. Abstract
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Mokhless, E. M., and A. H. Barkawi, "T3/T4 [thyroid hormones] ratio in relation to growth rate of Egyptian buffaloes during the second year of age", Annals of Agricultural Science, Moshtohor, vol. 28, 1990. Abstract
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Abouhmad, A., G. Mamo, T. Dishisha, M. A. Amin, and R. Hatti-Kaul, "T4 lysozyme fused with cellulose-binding module for antimicrobial cellulosic wound dressing materials", Journal of Applied Microbiology, vol. 121, no. 1, pp. 115–125, 2016. AbstractWebsite
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