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Khaled, H., N. Abeed, D. Ragab, A. El-Hadidy, K. Hussien, and M. Hosny, "RV Outflow Tract Pacing Versus RV Apical Pacing. Pathophysiologic Effects & Prognostic Implications", The Medical Journal of Cairo university , vol. 74, issue 2, 2006.
Abdel-Naim, A. B., A. A. Alghamdi, M. M. Algandaby, F. A. Al-Abbasi, A. M. Al-Abd, B. G. Eid, H. M. Abdallah, and A. M. El-Halawany, "Rutin Isolated from Chrozophora tinctoria Enhances Bone Cell Proliferation and Ossification Markers", Oxidative medicine and cellular longevity, vol. 2018: Hindawi, 2018. Abstract
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El-Maadawy, W. H., S. S. H. el-Din, S. M. Ezzat, O. A. Hammam, M. M. Safar, S. Saleh, and N. M. El-Lakkany, "Rutin Ameliorates Hepatic Fibrosis via Targeting Hepatic Stellate Cells’ Activation, Proliferation and Apoptosis ", Journal of Herbs, Spices & Medicinal Plants , vol. 27, issue 3, pp. 322–341, 2021. rutin_walaa_elmadawy.pdf
Mansour, A. M., R. M. Khaled, E. Khaled, S. K. Ahmed, O. S. Ismael, A. Zeinhom, and H. Magdy, "Ruthenium(II) carbon monoxide releasing molecules: Structural perspective, antimicrobial and anti-inflammatory properties", Biochemical Pharmacology, pp. 114991, 2022.
Hassan, H. K., N. F. Atta, M. M. Hamed, and A. G. T. and Jacob, "Ruthenium nanoparticles-modified reduced graphene prepared by a green method for highperformance supercapacitor application in neutral electrolyte", RSC Advances, vol. 7, pp. 11286-11296, 2017.
Hassan, H. K., N. F. Atta, M. Hamed, A. Galal, and T. Jacob, "Ruthenium nanoparticles-modified reduced graphene prepared by a green method for high-performance supercapacitor application in neutral electrolyte,", RSC advances, vol. 7, pp. 11286-11296, 2017.
Aboul-Enein, A. M., and D. Schulte-Frohlinde, "Ruthenium complexes interaction with nucleic acids and DNA damage via photosensitized radical production", International Symposium “Free-Radical- Induced Damage to DNA”, , Mulheim a.d Ruhr, West Germany, , 25-30 Sept, 1980.
El-Sheikh, N., "Russian Strategy in the Middle East", Al-Siyassa Al-Dawliya, vol. 209, 2017.
Abbass, M. M. S., and R. A. A. Moneim, "RUSSELL BODIES DEVELOPMENT IN ASSOCIATION WITH APOPTOTIC CHANGES IN DIABETIC HUMAN GINGIVA", Egyptian Dental Journal, 2014. AbstractRUSSELL BODIES DEVELOPMENT IN ASSOCIATION WITH APOPTOTIC CHANGES IN DIABETIC HUMAN GINGIVA.pdf

Background: Periodontal disease is considered the sixth major complication of diabetes mellitus. Apoptosis plays a functional role in limiting diabetic repair through diabetes-enhanced caspase-3 activity. The immune system has been shown to play an important role in the initiation and progression of periodontal disease. The fact that diabetics are more susceptible to infections suggests that immunologic capability may be deranged and the inflammatory process is enhanced in term of increased level of immunoglobulins. Russell bodies, an uncommon finding that may be associated with chronic inflammatory conditions. T-cells might promote the formation of Russell bodies (Mott cells) through the release of soluble factors, such as IL-2 which acts in a paracrine fashion to support the survival and function of regulatory T – cells (Tregs).
Methods: The aim of the study was to determine the adaptive apoptotic and inflammatory alterations accompanying diabetes in human gingival. To fulfill this objective, gingival biopsies (one per person) were collected from 10 diabetic patients (Type 2 diabetes mellitus) with periodontitis (Diabetic group) and from 10 donors with no known history of diabetes mellitus or periodontitis (Control group).The sections were examined histologically, immunohistochemically and by the direct immunofluorescence technique.
Results: Histopathological examination of the diabetic gingiva showed the association of Russell bodies with the numerous inflammatory cells detected in the lamina propria. This was further assured by increased reaction for CD138. Also, there was increased immunoreactivity for caspase-3 and IL-2. The histomorphometric analysis data supported the immunohistochemical results as there has been a high significant increase in the area percentage of caspase-3, CD-138 and IL-2 immunoreaction in the gingiva of diabetic group in comparison to the control group. Immunofluorescence labeling revealed increased reaction for IgA and IgM in the inflammatory cells and Russell bodies.
Conclusions: Diabetes enhanced apoptosis results in a cascade of events; starting by inflammation and formation of Mott cells (Russell bodies) in addition to deterioration of the immune system in the form of increased immunoglobulins.

Abdel-Sattar, E., S. A. EL-Maraghy, R. S. El-Dine, and S. M. Rizk, "Russelioside B, a pregnane glycoside ameliorates hyperglycemia in streptozotocin induced diabetic rats by regulating key enzymes of glucose metabolism. 3", Chemico-Biological Interactions. , vol. 252, pp. 47-53, 2016.
Abdel-Sattar, E., S. A. EL-Maraghy, R. S. El-Dine, and S. M. Rizk, "Russelioside B, a pregnane glycoside ameliorates hyperglycemia in streptozotocin induced diabetic rats by regulating key enzymes of glucose metabolism", Chemico-biological interactions, vol. 252: Elsevier, pp. 47-53, 2016. Abstract
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Abdel-Sattar, E., S. A. EL-Maraghy, R. S. El-Dine, and S. M. Rizk, "Russelioside B, a pregnane glycoside ameliorates hyperglycemia in streptozotocin induced diabetic rats by regulating key enzymes of glucose metabolism", Chemico-Biological Interactions, vol. 252: Elsevier, pp. 47–53, 2016. Abstract
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El-Shiekh, R. A., and et al, "Russelioside B Protects Against Ethanol-Induced Gastric Ulcer via Modulation of Heat Shock Protein-70 and Vascular Endothelial Growth Factor", Steroids, vol. 165 , pp. 108759 , 2021.
EL-Maraghy, S. A., R. S. El-Dine, S. M. Rizk, and E. Abdel-Sattar, Russelioside B from Caralluma quadrangula improved hepatic glucose metabolism in diabetic rats, , Submitted. Abstract
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Abdel-Sattar., E., Shohda A. EL-Maraghy, R. S. El-Dine, and S. M. Rizk, "Russelioside B from Caralluma quadrangula Improved Glucose Metabolism in the Liver of Streptozotocin- Diabetic Rats ", Chemico-Biological Interactions , vol. 252, pp. 47-53, 2016. russelioside_b_a_pregnane_glycoside_ameliorates_hyperglycemia_in.pdf
syzan Nasrat, E. Heekal, and E. A. S. Khalifa, "Rural youth alienation and the influence of some aspects", Al-Azhar Journal of Agricultural Science Sector Research, vol. 21, pp. 1-15, 2014. Abstract
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Elsayed, R. G., and E. M. El-Shafie, "Rural Women’s Knowledge, Attitudes, and Practices (KAP) pertaining to Highly Pathogenic Avian Influenza (H5N1 HPAI) in Qalubiya Governorate, Nile Delta, Egypt", 20th EUROPEAN SEMINAR of EXTENSION EDUCATION Private - public partnerships for advisory services in Europe Proceedings of the 20th ESEE Finland , Helsinki, Finland, 2011. radwa_ghoniem_esee.pdf
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Abdel-Aal, M. H., E. M. El-Shafie, and M. E. Abdel-Wahab, "Rural Households’ Adoption of Solid Waste Management Practices in Behera Governorate", Agric. Sci. Mansoura Univ., vol. 33, issue 6, pp. 4391-4402, 2008.
Imam, H., F. A. el-soud, I. Helmy, and A. Attia, "RURAL ADOLESCENT'S PERCEPTION TOWARD PREMARITAL SCREENING AND COUNSELING: A SUGGESTIVE PLAN OF ACTION", WIDU Healthcare Review, Magazine, 2009. rural_adolescen1.doc
El Damaty, A., S. Langner, and H. W. S. Schroeder, "Ruptured massa intermedia secondary to hydrocephalus: a case report", World Neurosurgery, 2017. AbstractWebsite

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Mahmoud, A. F., M. M. E. Raeia, and M. A. A. Elmakarem, "Rupture Diaphragm:Early Diagnosis and management", Journal Of The Egyptian Society Of Cardio-Thoracic Surgery, vol. 25, issue 2, pp. 163-170, 2017.
, RUNX2 and WWOX genes as molecular biomarkers and candidates for targeted therapy in Egyptian patients with primary conventional osteosarcoma, , 2016. RUNX2 and WWOX genes as molecular biomarkers and candidates for targeted therapy in Egyptian patients with primary conventional osteosarcoma.pdf
Adnan Awad, S., O. Dufva, A. Ianevski, B. Ghimire, J. Koski, P. Maliniemi, D. Thomson, A. Schreiber, C. A. Heckman, P. Koskenvesa, et al., "RUNX1 mutations in blast-phase chronic myeloid leukemia associate with distinct phenotypes, transcriptional profiles, and drug responses", Leukemia, vol. 35, no. 4: Nature Publishing Group, pp. 1087–1099, 2021. Abstract
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Elsayed, W., S. Salem, S. Aboul Naga, R. Khedr, M. Tantawy, K. Shaaban, and I. Sidhom, "RUNX1 AMPLIFICATION IN EGYPTIAN PEDIATRIC PATIENTS WITH PRECURSOR-B ACUTE LYMPHOBLASTIC LEUKEMIA", PEDIATRIC BLOOD & CANCER, vol. 66: WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2019. Abstract
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A., B., A. A., E. A., E. R., A. A., and S. S, "Runtime Self-Monitoring Approach of Business Process Compliance in Cloud Environments", Cluster Computing, vol. 18, issue 4, pp. 1503-1526, 2015.
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