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Isaac, S. K., The Quest for Inter-Cultural Dialogue In the Euro-Mediterranean Region: Opportunities and Challenges, , Florence, Robert Schuman Centre for Advanced Studies (RSCAS), 2010.
Sakr, S., A. Awad, and M. Kunze, "Querying Process Models Repositories by Aggregated Graph Search", Business Process Management Workshops, pp. 573-585, 2012. Abstract
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Awad, A., and S. Sakr, "Querying Graph-Based Repositories of Business Process Models", Database Systems for Advanced Applications, 15th International Conference, {DASFAA} 2010, International Workshops: GDM, BenchmarX, MCIS, SNSMW, DIEW, UDM, Tsukuba, Japan, April 1-4, 2010, Revised Selected Papers, vol. 6193: Springer, pp. 33–44, 2010. Abstract
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Ismail, A. S., H. Al-Feel, and H. M. O. Mokhtar, "Querying DBpedia Using HIVE-QL", 14th International Conference on Telecommunications and Informatics (TELE-INFO '15), Sliema,Malta, August 17-19, 20, 2015.
ElGhazaly, T., and A. Fahmy, "Query Translation and Expansion for Searching Normal and OCR-Degraded Arabic Text", Computational Linguistics and Intelligent Text Processing: Springer, pp. 481–497, 2009. Abstract
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Shaalan, K., S. Al-Sheikh, and F. Oroumchian, "Query Expansion Based-on Similarity of Terms for Improving Arabic Information Retrieval", Intelligent Information Processing VI, vol. 385, Berlin Heidelberg, Springer, pp. 167-176, 2012. Abstractquery_arabic_iip_ifip.pdf

This research suggests a method for query expansion on Arabic Information Retrieval using Expectation Maximization (EM). We employ the EM algorithm in the process of selecting relevant terms for expanding the query and weeding out the non-related terms. We tested our algorithm on INFILE test collection of CLLEF2009, and the experiments show that query expansion that considers similarity of terms both improves precision and retrieves more relevant documents. The main finding of this research is that we can increase the recall while keeping the precision at the same level by this method.

Abdelnour, S. A., R. A. Sindi, M. A. E. El-Hack, N. E. Khalifa, A. F. Khafaga, A. E. Noreldin, H. Samir, V. Tufarelli, C. Losacco, M. Gamal, et al., "Quercetin: Putative effects on the function of cryopreserved sperms in domestic animals", Reproduction in Domestic Animals , vol. 58, issue (2), pp. 191–206, 2023.
AbdEl-Gawad, H. M., and A. E. Khalifa, "Quercetin, coenzyme Q10, and L-canavanine as protective agents against lipid peroxidation and nitric oxide generation in endotoxin-induced shock in rat brain.", Pharmacological Research 04/2001; 43(3):257-63. , vol. 43, issue 3, pp. 257- 263, 2001.
Eleyan, M., M. A. El-Desouky, K. A. Ibrahim, and H. A. Daboun, "Quercetin Suppresses Apoptotic Genes Expression and DNA Fragmentation Induced by Nano-rich Diesel Exhaust Particles in the Fetal Brain", Merit Research Journal of Medicine and Medical Sciences, vol. 6, issue 7, pp. 1-9, 2018.
Zaki, H. F., A. M. Agha, and M. T. Khayyal, "Quercetin Reduces Inflammation in Adjuvant-Induced Arthritis: Possible Mechanisms Involved", 52nd annual conference of the Egyptian society of pharmacology and experimental therapeutics, Cairo University, 10 March, 2012.
Alqahtani, S. M., A. F. Dawood, S. S. Kamar, M. A. Haidara, A. M. Shams Eldeen, M. Dallak, B. Al-Ani, and H. A. Ebrahim, "Quercetin and Resveratrol are Associated with the Downregulation of TNF-a/NF-kB/iNOS Axis-Mediated Acute Liver Injury in Rats Induced by Paracetamol Poisoning", Int. J. Morphol, vol. 41, issue 1, pp. 79-84,, 2023.
Abdelrahman, R. E., A. A. A. Khalaf, M. A. Elhady, Marwa A Ibrahim, E. I. Hassanen, and P. A. Noshy, "Quercetin ameliorates ochratoxin A-Induced immunotoxicity in broiler chickens by modulation of PI3K/AKT pathway.", Chemico-biological interactions, vol. 351, pp. 109720, 2022. Abstract

Ochratoxin A (OTA) is a fungal secondary metabolite produced by certain species of Aspergillus and Penicillium, and exerts immunosuppressive effect on humans and animals. Quercetin (QUE) is one of the flavonoids produced as a plant-secondary metabolite. The present study was designed to evaluate the efficacy of QUE against the immunotoxic hazard of OTA in broiler chickens. Forty one-day-old broiler chicks were randomly and equally allocated into four groups; control, OTA (0.5 mg/kg feed), QUE (0.5 g/kg feed) and OTA + QUE (0.5 mg/kg OTA + 0.5 g/kg QUE). The results revealed that dietary OTA induced a significant decrease in the antibody response to Newcastle Disease (ND), Infectious Bronchitis (IB) and Avian Influenza (AI) vaccination and in the lymphoproliferative response to Phytohemagglutinin-P (PHA-P). Ochratoxin A also induced oxidative stress and lipid peroxidation in the bursa of Fabricius, spleen and thymus tissues of chickens as demonstrated by decreased CAT and GSH levels and increased TBARS content. In addition, administration of OTA resulted in apoptosis, which was evident by the increased expression level of PTEN, Bax and Caspase-3 genes and decreased expression level of PI3K, AKT and Bcl-2 genes. Furthermore, exposure to OTA resulted in various pathological lesions in the bursa of Fabricius, spleen and thymus of chickens. On the other hand, administration of QUE ameliorated most of the immunotoxic effects of OTAby its immunomodulatory, antioxidant and anti-apoptotic activities. Taken together, the results suggested that QUE potentially alleviated the OTA-induced immunotoxicity in broiler chickens, probably through amelioration of oxidative stress and activation of the PI3K/AKT signaling pathway.

Abdelrahman, R. E., A. A. A. Khalaf, M. A. Elhady, Marwa A Ibrahim, E. I. Hassanen, and P. A. Noshy, "Quercetin ameliorates ochratoxin A-Induced immunotoxicity in broiler chickens by modulation of PI3K/AKT pathway", Chemico-Biological Interactions, vol. 351, pp. 109720, 2022. AbstractWebsite

Ochratoxin A (OTA) is a fungal secondary metabolite produced by certain species of Aspergillus and Penicillium, and exerts immunosuppressive effect on humans and animals. Quercetin (QUE) is one of the flavonoids produced as a plant-secondary metabolite. The present study was designed to evaluate the efficacy of QUE against the immunotoxic hazard of OTA in broiler chickens. Forty one-day-old broiler chicks were randomly and equally allocated into four groups; control, OTA (0.5 mg/kg feed), QUE (0.5 g/kg feed) and OTA + QUE (0.5 mg/kg OTA + 0.5 g/kg QUE). The results revealed that dietary OTA induced a significant decrease in the antibody response to Newcastle Disease (ND), Infectious Bronchitis (IB) and Avian Influenza (AI) vaccination and in the lymphoproliferative response to Phytohemagglutinin-P (PHA-P). Ochratoxin A also induced oxidative stress and lipid peroxidation in the bursa of Fabricius, spleen and thymus tissues of chickens as demonstrated by decreased CAT and GSH levels and increased TBARS content. In addition, administration of OTA resulted in apoptosis, which was evident by the increased expression level of PTEN, Bax and Caspase-3 genes and decreased expression level of PI3K, AKT and Bcl-2 genes. Furthermore, exposure to OTA resulted in various pathological lesions in the bursa of Fabricius, spleen and thymus of chickens. On the other hand, administration of QUE ameliorated most of the immunotoxic effects of OTAby its immunomodulatory, antioxidant and anti-apoptotic activities. Taken together, the results suggested that QUE potentially alleviated the OTA-induced immunotoxicity in broiler chickens, probably through amelioration of oxidative stress and activation of the PI3K/AKT signaling pathway.

Mayada R. Farag 1, *, Attia A. A. Moselhy 2, Amany El-Mleeh 3, Samira H. Aljuaydi 4, Tamer Ahmed Ismail 5, and Alessandro Di Cerbo 6, Quercetin Alleviates the Immunotoxic Impact Mediated by Oxidative Stress and Inflammation Induced by Doxorubicin Expo-Sure in Rats, , 2021.
Eleyan, M., M. A. El-Desouky, K. A. Ibrahim, H. A. Daboun, and H. A. Abdelrahman, "Quercetin alleviates the adverse effects of nano-rich diesel exhaust particles on pregnancy and petal growth in rats.", Bioscience Research, vol. 15, issue 4, pp. 4590-4602, 2018. article.pdf
Eleyan, M., M. A. El-Desouky, K. A. Ibrahim, H. A. Daboun, and H. A. Abdelrahman, "Quercetin alleviates the adverse effects of nano-rich diesel exhaust particles on pregnancy and petal growth in rats.", Bioscience Research, vol. 15, issue 4, pp. 4590-4602, 2018.
Walaa, M. S., "Quercetin Alleviates Red Bull Energy Drink-Induced Cerebral Cortex Neurotoxicity via Modulation of Nrf2 and HO-1", Oxidative Medicine and Cellular Longevity, vol. 2021, pp. 1-13, 2021.
Behairy, A., M. M. Hashem, K. Abo-EL-Sooud, A. E. El-Metwally, B. A. Hassan, and Y. M. Abd-Elhakim, "Quercetin Abates Aluminum Trioxide Nanoparticles and Lead Acetate Induced Altered Sperm Quality, Testicular Oxidative Damage, and Sexual Hormones Disruption in Male Rats.", Antioxidants (Basel, Switzerland), vol. 11, issue 11, 2022. Abstractantioxidants-11-02133.pdf

This study examined the effects of exposure to lead acetate (PbAc) and/or aluminum trioxide nanoparticles (AlONPs) on testicular function. Additionally, the probable reproprotective effects of quercetin (QTN) against AlONPs and PbAc co-exposure in male Sprague Dawely rats were assessed. AlONPs (100 mg/kg b.wt.), PbAc (50 mg/kg b.wt.), and QTN (20 mg/kg b.wt.) were orally administered for 60 days. Then, spermiogram, histopathological examinations of the testis and accessory glands, and immunohistochemical detection of androgen receptors (AR) and tumor necrotic factor alpha (TNF-α) were achieved. Moreover, serum levels of male sex hormones and testicular levels of antioxidant indices were estimated. The results showed that AlONP and/or PbAc caused significant sperm abnormalities, testicular oxidative stress, and histopathological changes. Furthermore, serum testosterone, LH, and FSH levels significantly decreased, while estradiol levels significantly increased. The AlONPs and/or PbAc co-exposed group had more obvious disturbances. Furthermore, QTN co-administration significantly reversed the AlONPs and PbAc-induced testicular histopathological alterations, reduced antioxidant defenses, and altered AR and TNF-α immune expression in testicular tissues. Conclusively, AlONPs and/or PbAc evoked testicular dysfunction by inducing oxidative injury and inflammation. However, QTN oral dosing effectively mitigated the negative effects of AlONPs and PbAc by suppressing oxidative stress and inflammation and improving the antioxidant defense system.

Behairy, A., M. M. Hashem, K. Abo-EL-Sooud, A. E. El-Metwally, B. A. Hassan, and Y. M. Abd-Elhakim, "Quercetin Abates Aluminum Trioxide Nanoparticles and Lead Acetate Induced Altered Sperm Quality, Testicular Oxidative Damage, and Sexual Hormones Disruption in Male Rats.", Antioxidants (Basel, Switzerland), vol. 11, issue 11, 2022. Abstract

This study examined the effects of exposure to lead acetate (PbAc) and/or aluminum trioxide nanoparticles (AlONPs) on testicular function. Additionally, the probable reproprotective effects of quercetin (QTN) against AlONPs and PbAc co-exposure in male Sprague Dawely rats were assessed. AlONPs (100 mg/kg b.wt.), PbAc (50 mg/kg b.wt.), and QTN (20 mg/kg b.wt.) were orally administered for 60 days. Then, spermiogram, histopathological examinations of the testis and accessory glands, and immunohistochemical detection of androgen receptors (AR) and tumor necrotic factor alpha (TNF-α) were achieved. Moreover, serum levels of male sex hormones and testicular levels of antioxidant indices were estimated. The results showed that AlONP and/or PbAc caused significant sperm abnormalities, testicular oxidative stress, and histopathological changes. Furthermore, serum testosterone, LH, and FSH levels significantly decreased, while estradiol levels significantly increased. The AlONPs and/or PbAc co-exposed group had more obvious disturbances. Furthermore, QTN co-administration significantly reversed the AlONPs and PbAc-induced testicular histopathological alterations, reduced antioxidant defenses, and altered AR and TNF-α immune expression in testicular tissues. Conclusively, AlONPs and/or PbAc evoked testicular dysfunction by inducing oxidative injury and inflammation. However, QTN oral dosing effectively mitigated the negative effects of AlONPs and PbAc by suppressing oxidative stress and inflammation and improving the antioxidant defense system.

Safwat, N. A., M. O. N. A. T. KASHEF, R. K. Aziz, K. F. Amer, and M. A. Ramadan, "Quercetin 3-O-glucoside recovered from the wild Egyptian Sahara plant, Euphorbia paralias L., inhibits glutamine synthetase and has antimycobacterial activity", Tuberculosis, vol. 108: Churchill Livingstone, pp. 106–113, 2018. Abstract

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