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Twfik, F. M., A. M. Sulieman, A. S. Barakat, M. S. Abbas, and H. M. Sobhy, "Production of healthy snacks from barley, chickpea, lettuce seeds and herb distributed in Egypt", Arab Universities Journal of Agricultural Sciences, vol. 24, issue 2: The Society of Arab Colleges of Agriculture, pp. 513-523, 2016. Abstract
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Twfik, F. M., A. M. Sulieman, A. S. Barakat, M. S. Abbas, and H. M. Sobhy, "Production of healthy snacks from barley, chickpea, lettuce seeds and herb distributed in Egypt", Arab Universities Journal of Agricultural Sciences, vol. 24, no. 2: The Society of Arab Colleges of Agriculture, pp. 513–523, 2016. Abstract
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Uemura, K., N. Funabiki, T. Nakanishi, and T. Farag, "A proposal of a routing tree generation algorithm for minimizing the maximum delay in wireless mesh networks", 2007-10-NS, vol. 107, no. no. 261, NS2007-90: IEICE Tech. Rep., pp. pp–57, 2007. Abstract
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Uemura, K., N. Funabiki, T. Nakanishi, and T. Farag, "A proposal of a routing tree generation algorithm for minimizing the maximum delay in wireless mesh networks", 2007-10-NS, vol. 107, no. no. 261, NS2007-90: IEICE Tech. Rep., pp. pp–57, 2007. Abstract
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undefined, M.A.Khalf, T.F.Ismail, and E. M. Ismaail, "Pro and Retrospective Epidemiological Situation of Avian Influenza in Egypt", European Journal of Academic Essays 3(7): 254-259, 2016 , vol. 3(7): 254-259, 2016, pp. 254-259, 2016 , 2016. ejae-1611-543.pdf
undefined, M. A. Mostafa, and A. M. F. Attia, "Pathological Studies on Fungi Associated with Diseased Safflower Seedling and their Control. ", Egyptian journal of phytopathology, 2011.
undefined, T. M. Abdel-Rahman, I. M. Kamel, E. A. Elwi, and M. A. Sayed, "Purification and characterization of nematicidal extracellular collagenase produced by the nematophagous fungud Arthrobotrys oligospora", Bull. Fac. Sci., Cairo Univ. , vol. 75, issue c, pp. 75-85, 2007.
undefined, Parathormone levels and Cardiac functions in patients with beta thalassemia major, , Cairo, Cairo university, 2012.
Ungefroren, H., A. Hyder, H. Hinz, S. Groth, H. Lange, K. F. M. El-Sayed, S. Ehnert, A. K. Nüssler, F. Fändrich, and F. Gieseler, "Pluripotency gene expression and growth control in cultures of peripheral blood monocytes during their conversion into programmable cells of monocytic origin (PCMO): evidence for a regulatory role of autocrine activin and TGF-β", PloS one, vol. 10, issue 2: Public Library of Science, 2015. Abstract
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Ungefroren, H., A. Hyder, H. Hinz, S. Groth, H. Lange, K. F. M. El-Sayed, S. Ehnert, A. K. Nüssler, F. Fändrich, and F. Gieseler, "Pluripotency gene expression and growth control in cultures of peripheral blood monocytes during their conversion into programmable cells of monocytic origin (PCMO): evidence for a regulatory role of autocrine activin and TGF-β", PLoS One, vol. 10, issue 2: Public Library of Science San Francisco, CA USA, pp. e0118097, 2015. Abstract
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Ungefroren, H., A. Hyder, H. Hinz, S. Groth, H. Lange, K. F. M. El-Sayed, S. Ehnert, A. K. Nüssler, F. Fändrich, and F. Gieseler, "Pluripotency gene expression and growth control in cultures of peripheral blood monocytes during their conversion into programmable cells of monocytic origin (PCMO): evidence for a regulatory role of autocrine activin and TGF-β", PloS one, vol. 10, issue 2: Public Library of Science San Francisco, CA USA, pp. e0118097, 2015. Abstract
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Ungefroren, H., A. Hyder, M. Schulze, K. M Fawzy El-Sayed, E. Grage-Griebenow, A. K. Nussler, and F. Fändrich, "Peripheral blood monocytes as adult stem cells: molecular characterization and improvements in culture conditions to enhance stem cell features and proliferative potential", Stem cells international, vol. 2016: Hindawi Publishing Corporation, 2015. Abstract
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Ungefroren, H., A. Hyder, M. Schulze, K. M Fawzy El-Sayed, E. Grage-Griebenow, A. K. Nussler, and F. Fändrich, "Peripheral Blood Monocytes as Adult Stem Cells: Molecular Characterization and Improvements in Culture Conditions to Enhance Stem Cell Features and Proliferative Potential", Stem Cells International, vol. 2016: Hindawi Publishing Corporation, 2015. Abstract
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Ungefroren, H., A. Hyder, M. Schulze, Fawzy El-Sayed, K, M. Karim, E. Grage-Griebenow, A. K. Nussler, and F. Fändrich, "Peripheral blood monocytes as adult stem cells: molecular characterization and improvements in culture conditions to enhance stem cell features and proliferative potential", Stem cells international, vol. 2016: Hindawi, 2016. Abstract
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Ungefroren, H., A. Hyder, M. Schulze, K. M Fawzy El-Sayed, E. Grage-Griebenow, A. K. Nussler, and F. Fändrich, "Peripheral blood monocytes as adult stem cells: molecular characterization and improvements in culture conditions to enhance stem cell features and proliferative potential", Stem cells international, vol. 2016, issue 1: Hindawi Publishing Corporation, pp. 7132751, 2016. Abstract
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Ungefroren, H., A. Hyder, M. Schulze, K. M Fawzy El-Sayed, E. Grage-Griebenow, A. K. Nussler, and F. Fändrich, "Peripheral blood monocytes as adult stem cells: molecular characterization and improvements in culture conditions to enhance stem cell features and proliferative potential", Stem cells international, vol. 2016: Hindawi, 2016. Abstract
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Ungefroren, H., A. Hyder, H. Hinz, S. Groth, H. Lange, K. F. M. El-Sayed, S. Ehnert, A. K. Nüssler, F. Fändrich, and F. Gieseler, "Pluripotency gene expression and growth control in cultures of peripheral blood monocytes during their conversion into programmable cells of monocytic origin (PCMO): evidence for a regulatory role of autocrine activin and TGF-$\beta$", PloS one, vol. 10, no. 2: Public Library of Science, pp. e0118097, 2015. Abstract
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and Unuofin J.O., Moubasher H.A., O. N. A. I. U. U., "Production of polyextremotolerant laccase by Achromobacter xylosoxidans HWN16 and Citrobacter freundii LLJ16", Biotechnology Reports . 22 e00337. , vol. 22, pp. e00337, 2019.
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Vajawat, M., and et al, "Pyogenic granuloma:An unusual presentation. (Prof. Emad Daif was a peer reviewer for this article)", British Journal of Medicine and Medical Research, vol. 10, issue 3, pp. 1-5, 2015.
Van Sciver, S., J. Derr, A. Khalil, and I. Sviatoslavsky, "Preliminary magnet design for a stellarator fusion reactor", IEEE Transactions on Magnetics, vol. 17, issue 5: IEEE, pp. 1703-1706, 1981. Abstract
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Van Sciver, S., J. Derr, A. Khalil, and I. Sviatoslavsky, "Preliminary magnet design for a stellarator fusion reactor", IEEE Transactions on Magnetics, vol. 17, no. 5: IEEE, pp. 1703–1706, 1981. Abstract
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Veksler, D. B., A. V. Muraviev, T. A. Elkhatib, K. N. Salama, and M. S. Shur, "Plasma wave FET for sub-wavelength THz imaging", 2007 International Semiconductor Device Research Symposium: IEEE, pp. 1-2, 2007. Abstract
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Vergote, I., I. Boere, A. Casado, C. Coens, and E. Shash, "PHASE I STUDY OF THE EORTC-GCG ON PAZOPANIB WITH WEEKLY PACLITAXEL AND CARBOPLATIN IN PLATINUM-RESISTANT OVARIAN CARCINOMA", INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, vol. 24, no. 9: LIPPINCOTT WILLIAMS & WILKINS 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA, pp. 475–476, 2014. Abstract
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Veronica Strong, Sergey Dubin, M. E. - K. F., and B. W. R. K. H. B. Andrew Lech, Yue Wang, "Patterning and Electronic Tuning of Laser Scribed Graphene for Flexible All-Carbon Devices", ACS Nano, vol. 6, pp. 1395-1403, 2012. acs_nano-2012.pdf
Veys, K., M. A. Elmonem, L. van den Heuvel, W. A. Gahl, and E. Levtchenko, "Plasma chitotriosidase enzyme activity as a novel therapeutic monitor for cysteamine treatment in nephropathic cystinosis: A retrospective validation study.", Molecular genetics and metabolism, vol. 142, issue 1, pp. 108454, 2024. Abstract

BACKGROUND: Cystine-depleting therapy in nephropathic cystinosis is currently monitored via the white blood cell cystine assay, although its application and usefulness are limited by practical and technical issues. Therefore, alternative biomarkers that are widely available, more economical and less technically demanding, while reliably reflecting long-term adherence to cysteamine treatment, are desirable. Recently, we proposed chitotriosidase enzyme activity as a potential novel biomarker for the therapeutic monitoring of cysteamine treatment in cystinosis. In this study, we aimed to validate our previous findings and to confirm the value of chitotriosidase in the management of cystinosis therapy.

MATERIALS & METHODS: A retrospective study was conducted on 12 patients treated at the National Institutes of Health Clinical Center and followed up for at least 2 years. Plasma chitotriosidase enzyme activity was correlated with corresponding clinical and biochemical data.

RESULTS: Plasma chitotriosidase enzyme activity significantly correlated with WBC cystine levels, cysteamine total daily dosage and a Composite compliance score. Moreover, plasma chitotriosidase was a significant independent predictor for WBC cystine levels, and cut-off values were established in both non-kidney transplanted and kidney transplanted cystinosis patients to distinguish patients with a good versus poor compliance with cysteamine treatment. Our observations are consistent with those of our previous study and validate our findings.

CONCLUSIONS: Chitotriosidase enzyme activity is a valid potential alternative biomarker for monitoring cysteamine treatment in nephropathic cystinosis patients.

SYNOPSIS: Chitotriosidase enzyme activity is a valid potential alternative biomarker for monitoring cysteamine treatment in nephropathic cystinosis patients.