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Yehia, T. A., A. A. Hegazi, M. A. Saleh, D. M. Ahmed, N. S. Zaied, and S. A. Hassan, "Physiological studies on development flower bud in vitro of'Le Conte'pear trees.", Middle East Journal of Scientific Research, vol. 12, issue 6: IDOSI Publications, pp. 864-869, 2012. Abstract
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Yehia, S. A., A. H. Elshafeey, and I. Elsayed, "Pulsatile systems for colon targeting of budesonide: In vitro and in vivo evaluation", Drug Delivery, vol. 18, issue 8, pp. 620-630, 2011.
Yehia, S. A., A. H. Elshafeey, A. ElMeshad, and H. A. Al-Bialey, "A Pharmaceutical Study on Different Approaches for Itopride Hydrochloride Sustainment: In-vitro and in-vivo evaluation", Journal of Chemical and Pharmaceutical Research, vol. 4, issue 2, pp. 1398-1412, 2012.
Yehia, S. A., A. H. Elshafeey, and I. Elsayed, "Pulsatile systems for colon targeting of budesonide: In vitro and in vivo evaluation", Drug Delivery, vol. 18, no. 8, pp. 620-630, 2011. AbstractWebsite

The purpose of this study is to increase the lag time and prevent release of budesonide, a corticosteroid drug used in Crohn's disease for the first 5h and efficiently deliver it to the colon. Eudragit S100 spray-coated capsules and pulsatile systems using tablet plugs of cellulose acetate butyrate (CAB), HPMC K4M, guar gum, and pectin were prepared. Eudragit S100-coated capsules released 80.62% after 5h. In pulsatile systems, decreasing the ratio of the polymer significantly increased the rate and extent of drug release. Spray-coating with EUD S100 decreased the extent of drug release to 48.41%, 69.94%, 80.58%, and 45.23% in CAB, HPMC K4M, pectin, and guar gum, respectively; however, the entire amount was released in the target area. In the presence of bacterial enzymes, selected formulas showed nearly 100% release. X-ray imaging performed to monitor the capsules throughout the GIT in human volunteers of the capsules and spray-coated pulsatile systems with 25% guar gum in the plug showed bursting in the transverse and ascending colon, respectively. Both formulations showed marked reduction in induced rabbit colitis model. © 2011 Informa Healthcare USA, Inc.

Yehia, N., A. H. M. E. D. M. ERFAN, A. Adel, A. El-Tayeb, W. M. M. Hassan, A. Samy, M. A. E. El-Hack, M. T. El-Saadony, K. A. El-Tarabily, and K. A. Ahmed, "Pathogenicity of three genetically distinct and highly pathogenic Egyptian H5N8 avian influenza viruses in chickens", Poultry Science, vol. 101:101662, 2022.
Yehia, S. A., A. H. Elshafeey, A. El Meshad, and H. A. Al-Bialey, "A pharmaceutical study on different approaches for itopride hydrochloride sustainment: In-vitro and in-vivo evaluation", Journal of Chemical and Pharmaceutical Research, vol. 4, no. 2, pp. 1398-1412, 2012. AbstractWebsite

Recent trends indicate that dosage form drug delivery systems are especially suitable for achieving sustained or delayed release oral formulations with low risk of dose dumping, flexibility of blending to attain different release patterns as well as reproducibility. One of the approaches toward this goal was to develop and formulate extended release matrix oral tablets of itopride hydrochloride (ITO) as a highly water soluble drug and to increase its gastric retention time. Matrix tablets of (ITO) were developed using different methods such as: (wetting granulation, direct compression, and coating compression), by using different types of polymers (hydroxypropyl methyl cellulose (HPMC) K15M, hydroxypropyl cellulose (HPC) low viscosity, Eudragit ® RL100, and Carnauba wax). The prepared tablets were evaluated according to various physicochemical characteristics such as: weight and thickness variation, drug content, hardness, friability, and in vitro drug release. Tablet weight variation ranged from 395 ± 0.34 to 409 ± 1.78 mg, thickness ranged from 3.16 ± 1.37 to 3.74 mm, drug content ranged from 94.5 ± 1.01% to 106.2 ± 0.08%, friability ranged from 0.04 ± 0.69 to 0.84 ± 0.45, and hardness ranged from 5.25 ± 0.25 to 8.80 ± 0.4 Kg/cm 2. Results indicated that drug release depended upon method of preparation and polymer type. Furthermore, in vivo testing of the optimum sustained release tablet formulation (F23) using coating compression by HPMC as coat was performed in human subjects, and determined and compared to that of a commercial oral tablet (Ganaton ®) as a reference formulation. The obtained the maximum plasma concentration (C max) and the area under the curve from zero to infinity (AUC ( 0-∞) values were higher following formulated tablet administration than after Ganaton ® administration. The percentage relative bioavailability of ITO from the selected formula in human volunteers was found to be 243% compared to Ganaton ®.

Yehia, S. A., A. H. Elshafeey, and I. Elsayed, "Pulsatile systems for colon targeting of budesonide: In vitro and in vivo evaluation", Drug Delivery, vol. 18, no. 8, pp. 620-630, 2011. AbstractWebsite

The purpose of this study is to increase the lag time and prevent release of budesonide, a corticosteroid drug used in Crohn's disease for the first 5h and efficiently deliver it to the colon. Eudragit S100 spray-coated capsules and pulsatile systems using tablet plugs of cellulose acetate butyrate (CAB), HPMC K4M, guar gum, and pectin were prepared. Eudragit S100-coated capsules released 80.62% after 5h. In pulsatile systems, decreasing the ratio of the polymer significantly increased the rate and extent of drug release. Spray-coating with EUD S100 decreased the extent of drug release to 48.41%, 69.94%, 80.58%, and 45.23% in CAB, HPMC K4M, pectin, and guar gum, respectively; however, the entire amount was released in the target area. In the presence of bacterial enzymes, selected formulas showed nearly 100% release. X-ray imaging performed to monitor the capsules throughout the GIT in human volunteers of the capsules and spray-coated pulsatile systems with 25% guar gum in the plug showed bursting in the transverse and ascending colon, respectively. Both formulations showed marked reduction in induced rabbit colitis model. © 2011 Informa Healthcare USA, Inc.

Yehia, R., and E. Rozaik, PREDICTION OF ROUGHNESS COEFFICIENT FOR AGED PIPES USING SIMULATION MODELS, , 2014. Abstract

Abstract
Many effort is exhausted lately in Egypt for adjusting data used to be introduced in a water distribution modeling software. One of these parameters that were very impressive in changing the results totally is the roughness coefficient (Hazen Williams C). The effect is seen obviously if the flows are increased so leads to higher head losses. These head losses would appear lower due to the fact that we are using uncertain value for roughness especially if we are using the standard roughness for new pipes.
The outcome from precise determination of roughness coefficient is adjusting water distribution network models to cope with real field values. The aim of this research is to relate C factor to head loss gradient so engineers can find a way to estimate C factor for aged pipes based in head loss gradient whatever was the network configuration.
The relationship of C factor to water quality parameters as chlorine decay is also discussed. Polynomial Equations relating chlorine concentration and Hazen Williams C factor is deduced.
A validation of Watergems leakage detection module (Darwin calibrator module) makes up a part of this research. And it is concluded that leak location can be found in a range of circle with a radius of 0.25km around point detected by Darwin Calibrator.
Equations of Colebrook and White are inserted in Watergems tables using user data extension tool to enter formulas to be calculated by software engine. This is a way provided to help get a fast estimate for roughness coefficient.
Keywords
C factor, leakage, chlorine decay, head loss gradient and aged pipes.

Yehia, S. A. a, M. S. b El-Ridi, M. I. a Tadros, and N. G. c El-Sherif, "Phenylalanine-free taste-masked orodispersible tablets of fexofenadine hydrochloride: Development, in vitro evaluation and in vivo estimation of the drug pharmacokinetics in healthy human volunteers", Pharmaceutical Development and Technology, vol. 20, no. 5, pp. 528-539, 2015. AbstractWebsite

Context: Fexofenadine hydrochloride (FXD) is a slightly soluble, bitter-tasting, drug having an oral bioavailability of 35%. The maximum plasma concentration is reached 2.6h (Tmax) post-dose. Objective: Developing taste-masked FXD orodispersible tablets (ODTs) to increase extent of drug absorption and reduce Tmax. Methods: Taste masking was achieved via solid dispersion (SD) with chitosan (CS) or sodium alginate (ALG). Fourier transform infrared spectroscopy, differential scanning calorimetry and X-ray diffraction were performed to identify physicochemical interactions and FXD crystallinity. Taste-masked FXD-ODTs were developed via addition of superdisintegrants (croscarmellose sodium or sodium starch glycolate, 5% and 10%, w/w) or sublimable agents (camphor, menthol or thymol; 10% and 20%, w/w) to FXD-SDs. ODTs were evaluated for weight variation, drug-content, friability, wetting, disintegration and drug release. Camphor-based (20%, w/w) FXD-ODT (F12) was optimized (F23) by incorporation of a more hydrophilic lubricant (Pruv®), visualized via scanning electron microscopy and evaluated for FXD pharmacokinetics in healthy volunteers relative to Allegra® tablets. Results: Based on gustatory sensation test, FXD-CS (1:1) and FXD-ALG (1:0.5) SDs were selected. Taste-masked FXD-ODTs had appropriate physicochemical properties. Drug release profiles of F23 and the phenylalanine-containing Allegra® ODT were similar (f2=96). Pores were observed following camphor sublimation. The pharmacokinetic studies proved F23 ability to increase extent of FXD absorption and reduce Tmax. © 2015 Informa Healthcare USA, Inc.

Yi Zhou, K. Xiao, Y. Wang, Alei Liang, and A. E. Hassanien, "A pso-inspired multi-robot map exploration algorithm using frontier-based strategy", International Journal of System Dynamics Applications (IJSDA), vol. 2, no. 2: IGI Global, pp. 1–13, 2013. Abstract
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Yi Zhou, K. Xiao, Y. Wang, Alei Liang, and A. E. Hassanien, "A pso-inspired multi-robot map exploration algorithm using frontier-based strategy", International Journal of System Dynamics Applications (IJSDA), vol. 2, no. 2: IGI Global, pp. 1–13, 2013. Abstract
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Yi Zhou, K. Xiao, Y. Wang, Alei Liang, and A. E. Hassanien, "A PSO-inspired Multi-Robot Map Exploration Algorithm Using Frontier-Based Strategy", International Journal of System Dynamics Applications,, vol. 2, issue 2, pp. 1-13, 2013. AbstractWebsite

Map exploration is a fundamental problem in mobile robots. This paper presents a distributed algorithm that coordinates a team of autonomous mobile robots to explore an unknown environment. The proposed strategy is based on frontiers which are the regions on the boundary between open and unexplored space. With this strategy, robots are guided to move constantly to the nearest frontier to reduce the size of unknown region. Based on the PSO model incorporated in the algorithm, robots are navigated towards remote frontier after exploring the local area. The exploration completes when there is no frontier cell in the environment. The experiments implemented on both simulated and real robot scenarios show that the proposed algorithm is capable of completing the exploration task. Compared to the conventional method of randomly selecting frontier, the proposed algorithm proves its efficiency by the decreased 60% exploration time at least. Additional experimental results show the decreased coverage time when the number of robots increases, which further suggests the validity, efficiency and scalability.

YM, E. S., "Pitfalls and pearls in paediatric glaucoma surgery", Nigerian Ophthalmology Society Annual meeting, Lagos, 2011.
Yoho, T. P., L. Butler, and J. E. Weaver, "Photodynamic killing of house flies fed food, drug, and cosmetic dye additives", Environmental Entomology, vol. 5, issue 1: Oxford University Press Oxford, UK, pp. 203-204, 1976. Abstract
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Yoho, T. P., L. Butler, and J. E. Weaver, "Photodynamic effect of light on dye-fed house flies: preliminary observations of mortality.", Journal of Economic Entomology, vol. 64, issue 4, pp. 972-973, 1971. Abstract
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Yoho, T. P., J. E. Weaver, and L. Butler, "Photodynamic action in insects. 1. Levels of mortality in dye-fed light-exposed house flies", Environmental Entomology, vol. 2, issue 6: Oxford University Press Oxford, UK, pp. 1092-1096, 1973. Abstract
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Yosry, A., G. Esmat, A. Omar, M. El-Serafy, W. Doss, A. El-Tawil, A. Ghaly, R. Kamel, H. Khalil, H. El-Gabaly, et al., "Pretransplantation MELD score does not predict recipient survival in adult living donor liver transplantation (LDLT).", LIVER TRANSPLANTATION, vol. 12, no. 5, pp. C80, MAY, 2006. Abstract
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Younes, A., M. F. Taher, I. Sidhom, W. Zekri, I. Zaky, H. Elfendy, A. N. Taher, S. A. Khedr, R. Gamal, and G. Ahmed, "Parotid gland masses: outcomes in the pediatric age group.", Journal of the Egyptian National Cancer Institute, vol. 35, issue 1, pp. 2, 2023. Abstract

BACKGROUND: Childhood parotid neoplasms appear to have different characteristics from adults. This point, in addition to the rarity of these tumors, reflects the challenges faced in diagnosing and treating parotid neoplasms in children.

PATIENTS AND METHODS: This retrospective study included all children who presented to the Children's Cancer Hospital Egypt (CCHE, 57357) with parotid masses from January 2008 to December 2020.

RESULTS: Twenty-one patients were included. Malignant neoplasms were found in 12 (57.1%) of which mucoepidermoid carcinoma was the most common. Benign neoplasms were found in 6 (28.6%) all of them were pleomorphic adenoma, and non-neoplastic lesions were found in 3 (14.3%). Superficial, deep, or total parotidectomy was performed according to the involved lobes. The facial nerve was sacrificed in three cases because of frank invasion by the tumor. Neck dissection was considered in clinically positive lymph nodes and/or T3/4 masses. Complications occurred in 7 (33.3%) all were of the malignant cases. Adjuvant radiotherapy was restricted to high-risk cases (7 cases). Recurrence occurred in two cases, and one patient died of distant metastasis. Fine needle aspiration cytology (FNAC) showed 88.9% sensitivity and 100% specificity for diagnosing malignant neoplasms. The correlation of radiological and pathological staging was fair (66.74% for overall staging).

CONCLUSIONS: Parotidectomy is the backbone treatment for benign and malignant pediatric parotid tumors. Neck nodal dissection should be considered after preoperative FNAC of suspicious nodes. Adjuvant radiotherapy is considered only in high-risk tumors. Preoperative FNAC of parotid masses and clinically suspicious lymph nodes is highly recommended.

Younes, A., H. El-Sherif, F. Gawish, and M. Mahmoud, "Potential of Hemianax ephippiger (Odonata-Aeshnidae) nymph as predator of Fasciola intermediate host, Lymnaea natalensis.", Asian pacific journal of tropical biomedicine , vol. 5, issue 8, pp. 671-675, 2015. potential_of_hemianax_ephippiger_......._as_predator_of_.....pdf
Younis, J. A., Nahla D El‑Sayed, and A. I. Kamel, "Prevalence of Subclinical Peripheral Vascular Disease in Obese Egyptian Patients", Indian Journal of Nuclear Medicine , vol. 32, issue 4, pp. 271-278, 2017. indianjnuclmed324271-5276859_143928.pdf
Younis, S. M., G. M. Nasr, and Y. F. Sharobeem, "Performance improvement of single and double acting mowers.", MJAE,, vol. 8, issue 4, 1991. Abstract
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Younis, R. A., D. K. Ibrahim, E. M.Aboul-Zahab, and A. ’fotouh El'Gharably, "Power Management Regulation Control Integrated with Demand Side Management for Stand-alone Hybrid Microgrid Considering Battery Degradation", International Journal of Renewable Energy Research, vol. 9, issue 4, pp. 1912-1923, 2019. Abstract

A new Power Management Regulation Control (PMRC) integrated with Demand Side Management (DSM) strategies is proposed to enhance the Energy Management System (EMS) of a stand-alone hybrid microgrid. The microgrid combines Wind and PV systems as Renewable Energy Sources (RES) with a hybrid Energy Storage System (ESS) of Battery and Fuel Cell/Electrolyzer set. Towards achieving Net Zero Energy Supply, such microgrid is adequate in remote and isolated new communities with AC controllable critical and noncritical loads. The proposed PMRC implies two-levels of control based on Multi-Agent System (MAS). The first level keeps the output power of each source in its maximum available output power by applying maximum power point tracking (MPPT) techniques. The second level is based on making proper decisions for achieving the power balancing regulation and coordination between the available and the reserve power of the RES and ESS under different operating modes. Valley Filling, Energy Conservation and Load Shifting are applied as DSM strategies to improve loads sustainability during system contingencies. Considering the battery as the most expensive part in the microgrid, the effectiveness of the proposed strategy is further verified by determining the maximum permissible estimated battery lifetime during the operation in all possible scenarios. Extensive simulation studies for various scenarios of microgrid operation in a year were carried out using Matlab/ Simulink with realistic typical wind speed, solar irradiation data and restricted by the status of available ESS.

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