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Radwan, G. N., S. A. H. A. R. LATIF, and N. A. H. L. A. AMIN, OCCUPATIONAL EXPOSURE, , 2014. occupational_exposure_to_shs_2014.pdf
Shaker, D., "OCCUPATIONAL EXPOSURE GENE INTERACTION :REVIEW ARTICLE", Egyptian Journal of Occupational Medicine, vol. 37, issue 1, pp. 61-78, 2013. occupational_exposure_gene_interaction.pdf
NH, Z., T. FM, F. SA, K. NA, F. M, and H. M, "Occupational exposure to aluminum and its amyloidogenic link with cognitive functions", Journal of Inorganic Biochemistry, vol. 139 , issue 1, pp. 57-64, 2014. occupational_exposure_to_aluminum_and_its_amyloidogenic_link_with_cognitive_functions.pdf
Zawilla, N. H., F. M. Taha, N. A. Kishk, S. A. Farahat, M. Farghaly, and M. Hussein, Occupational exposure to aluminum and its amyloidogenic link with cognitive functions, , 2014.
Reusken, C. B. E. M., E. A. B. A. Farag, B. L. Haagmans, K. A. Mohran, G. - J. Godeke, S. Raj, F. Alhajri, S. A. Al-Marri, H. E. Al-Romaihi, M. Al-Thani, et al., "Occupational Exposure to Dromedaries and Risk for MERS-CoV Infection, Qatar, 2013-2014.", Emerging infectious diseases, vol. 21, issue 8, pp. 1422-5, 2015. Abstract

We determined the presence of neutralizing antibodies to Middle East respiratory syndrome coronavirus in persons in Qatar with and without dromedary contact. Antibodies were only detected in those with contact, suggesting dromedary exposure as a risk factor for infection. Findings also showed evidence for substantial underestimation of the infection in populations at risk in Qatar.

Aziz, A. M. T. A., H. M. E. Zahed, S. H. Ahmed, and W. Fathy, "Occupational Exposure to Heavy Metal Initiate Carcinogenesis Though BRAF/KRAS Over Expression and DNA Methylation.", Journal of Chemical Health Risks , 2020. Abstract

Colorectal cancer (CRC) is a leading cause of death especially in industries worker.
The aim of this study: is to identify the role of heavy elements exposure on CRC DNA methylation.
Methods: The study was conducted on 25 CRC patients. Biopsies were taken by colonoscopy from malignant tissue and adjacent normal tissues for comparative assessment of BRAF/KRAS, methylated MLH1 and MGMT between the normal and malignant tissues by using real time PCR. In an attempt to identify wither heavy metal like Lead, Aluminum and Mn have a role in cancer development or not, we compared their levels in the serum of 25 CRC patients and 25 normal volunteers by using atomic absorption.
Results: The expressions of BRAF/KRAS, methylated MLH1 and MGMT were significantly higher in malignant tissues compared to normal tissues (p value<0.001). Additionally, the levels of lead and aluminum but not Mn were significantly higher in CRC patients compared to normal controls (p value<0.001). Lead and Aluminum were positively correlated with all studied parameters.
Conclusion: Heavy metals act as starting signals for carcinogenesis through DNA methylation.
Keywords: Colorectal cancer; Heavy metals; DNA methylation.

Ahmed, Z. A. M., Badawy.E.M, M. F. Badawy, G. Z. Rahel, and H. W. A, "OCCUPATIONAL HAZARDS OF EMITTED POLLUTANTS FROM POULTRY PRODUCTION FACILITIES", International Conference,Challenges in Poultry Industry (ICCPI), Faculty of veterinary medicine, Cairo University, Giza, EG., 13-15 November , 2013. occupational_hazards_zakia.pdf
Abo-el-Ata, G. A., B. M. S. Lotfy, S. A. Arnaout, T. - C. Aw, and R. - M. Locas, Occupational Health and Environmental Health Accreditation Standards for Hospitals and Healthcare Facilities, , Riadh- KSA, Supreme Committee of Health and Safety at GCC, 2012.
SF, H., "Occupational Health Care provided To Workers Exposed To Heat Related Industries", Egyptian Journal Of Occupational Medicine, vol. 37, issue 2, pp. 157-168, 2013. sawsan_heat.docx
Safty, E. A., S. Helal, A. N. Maksoud, and A. Samir, "Occupational Health Hazards among Double Sided Printed Circuit Board Manufacturers", British Journal of Applied Science & Technology, vol. 4, issue 11, pp. 1634-1643, 2014. full_paper_online.pdf
Safty, A. E., S. Helal, N. A. Maksoud, and A. Samir, "Occupational health hazards among double sided printed circuit board manufacturers", British journal of applied science and technology. , vol. 4, issue 11, 2014.
Safty, A. E., S. F. Helal, N. A. Maksoud, and A. M. Samir, "Occupational Health Hazards among Double Sided Printed Circuit Board Manufacturers.", British Journal of Applied Science and Technology., vol. 4, issue 11, pp. 1634-1643, 2014. occupational_health_hazards_among_double.pdf
Safty, E. A., S. Helal, A. N. Maksoud, and A. Samir, "Occupational Health Hazards among Double Sided Printed Circuit Board Manufacturers. ", British Journal of Applied Science & Technology, vol. 4, issue 11, pp. 1634-1643, 2014. occupational_health_hazards_among_double.pdf
AK, E. S., H. SF, M. NA, and S. Aisha, "OCCUPATIONAL HEALTH HAZARDS AMONG PRINTED CIRCUIT BOARD MANUFACTURES ", Britsh Journal of Applied Science and Technology , vol. 4:111635-1643(june, 2014.
MOHAMMED, H. A. N. A. A. H., S. A. N. E. Y. A. M. RIZK, and E. B. T. E. S. A. M. M. EBIED, "Occupational Health Hazards as Perceived by Poultry Processing Slaughterhouse Workers", Med. J. Cairo Univ.,, vol. Vol.86, issue 3, pp. 1129-1138, 2018. 06.pdf
Abo-el-Ata, G. A., and S. A. Arnaout, "Occupational Health in Egypt – Chapter 12 in the Joseph LaDou Book: "Occupational Medicine in Industrializing Countries"", Occupational Medicine in Industrializing Countries- State of the Art Reviews, Philadelphia- USA, Henley & Belfus, INC., 2002.
Abo-El-Ara, G. A., and H. Aziz, Occupational Health, Safety and Work Environment, , Cairo (Egypt), Workers' University, 2009.
, "Occupational Hearing Loss due to Noise Exposure and its relation with Heat shock protein 70 and its antibody.", The Medical Journal of Cairo University, vol. 78, issue 1, pp. 511-516, 2010.
Mohamed, R., W. Ibrahim, D. Sabry, and S. El-Jaafary, "Occupational metals exposure and cognitive performance among foundry workers using tau protein as a biomarker ", Neurotoxicology, issue 76, pp. 10-16, 2020.
Mohammed, R. S., W. Ibrahim, D. Sabry, and S. I. El-Jaafary, "Occupational metals exposure and cognitive performance among foundry workers using tau protein as a biomarker.", Neurotoxicology, vol. 76, pp. 10-16, 2020. Abstract

INTRODUCTION: Human exposure to heavy metals is a potential risk for developing cognitive impairment. Aluminum (Al) foundry is one of industries that involve occupational exposure to different metals.

AIM OF THE WORK: to evaluate the cognitive performance of Aluminum foundry workers in relation to different metals exposure.

MATERIALS AND METHODS: a cross sectional study conducted on 75 Al foundry workers and 75 non-occupationally exposed subjects as controls. Personal interview with specially designed questionnaire, Assessment of cognitive functions done using Montreal cognitive assessment (MocA), Stress, depression and sleep were also assessed. Serum levels of Aluminum (AL), Lead (Pb), manganese (Mn), Zinc (Zn) and tau protein were measured.

RESULTS: Exposed group showed significant increase in serum levels of Aluminum, lead, Manganese and tau protein, p value < 0.005 (mean ± SD 0.56 ± 0.18, 22.3 ± 5.01, 42.04 ± 7.4, 1.53 ± 0.58 Vs 0.36 ± 0.11, 13.4 ± 1.29, 39.4 ± 4.4, 1.03 ± 0.44 respectively) with significant decrease of zinc level compared to control (mean ± SD 46.4 ± 5.2 Vs 88.8 ± 6.04, p value 0.005). There was a significant decrease MocA scores among exposed population, (mean ± SD 24.4 ± 3.4 compared to 28.4 ± 1.3 in non exposed, p value < 0.005). which was affected by serum levels of lead, aluminum, manganese and tau protein (β -0.165, -8.958, -.286, -2.341 respectively and p < 0.005).Stress scores was higher in exposed workers than control but not affecting cognitive performance.

CONCLUSION: occupational exposure to metals can cause cognitive dysfunction which may be subtle, so there is a need for formal cognitive testing at baseline, and on regular intervals during working period. Serum tau protein could be used as a prognostic biomarker for the hazardous effect of occupational exposure to these metals on the neuronal cells.

Mohammed, R. S., W. Ibrahim, D. Sabry, and S. I. El-Jaafary, "Occupational metals exposure and cognitive performance among foundry workers using tau protein as a biomarker.", Neurotoxicology, vol. 76, pp. 10-16, 2020. Abstract

INTRODUCTION: Human exposure to heavy metals is a potential risk for developing cognitive impairment. Aluminum (Al) foundry is one of industries that involve occupational exposure to different metals.

AIM OF THE WORK: to evaluate the cognitive performance of Aluminum foundry workers in relation to different metals exposure.

MATERIALS AND METHODS: a cross sectional study conducted on 75 Al foundry workers and 75 non-occupationally exposed subjects as controls. Personal interview with specially designed questionnaire, Assessment of cognitive functions done using Montreal cognitive assessment (MocA), Stress, depression and sleep were also assessed. Serum levels of Aluminum (AL), Lead (Pb), manganese (Mn), Zinc (Zn) and tau protein were measured.

RESULTS: Exposed group showed significant increase in serum levels of Aluminum, lead, Manganese and tau protein, p value < 0.005 (mean ± SD 0.56 ± 0.18, 22.3 ± 5.01, 42.04 ± 7.4, 1.53 ± 0.58 Vs 0.36 ± 0.11, 13.4 ± 1.29, 39.4 ± 4.4, 1.03 ± 0.44 respectively) with significant decrease of zinc level compared to control (mean ± SD 46.4 ± 5.2 Vs 88.8 ± 6.04, p value 0.005). There was a significant decrease MocA scores among exposed population, (mean ± SD 24.4 ± 3.4 compared to 28.4 ± 1.3 in non exposed, p value < 0.005). which was affected by serum levels of lead, aluminum, manganese and tau protein (β -0.165, -8.958, -.286, -2.341 respectively and p < 0.005).Stress scores was higher in exposed workers than control but not affecting cognitive performance.

CONCLUSION: occupational exposure to metals can cause cognitive dysfunction which may be subtle, so there is a need for formal cognitive testing at baseline, and on regular intervals during working period. Serum tau protein could be used as a prognostic biomarker for the hazardous effect of occupational exposure to these metals on the neuronal cells.