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Yassin, N. A., M. Haroon, and A. E. Hamshary, "Methotrexate Hepatotoxicity in Children with Juvenile Idiopathic Arthritis: A Single-Center Study", Current Rheumatology Reviews, vol. 17, no. 2: Bentham Science Publishers, pp. 242–246, 2021. Abstract
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Yazeed, H. A. E., A. Hassan, R. E. A. Moghaieb, M. Hamed, and M. Refai, "Molecular Detection of Fumonisin-producing Fusarium Species in Animal Feeds Using Polymerase Chain Reaction (PCR)", Journal of Applied Sciences Research, , vol. 7, issue 4, pp. 420-427, 2011. molecular_detection_of_fumonisin.pdf
Yazeed, H. A. E., A. Hassan;, R. E. A. Moghaieb, M. Hamed, and M. Refai, "Molecular Detection of Fumonisin-producing Fusarium Species in Animal Feeds Using Polymerase Chain Reaction (PCR)", Journal of Applied Sciences Research, vol. 7 (4), pp. 420-427, 2011. journal_of_applied_science_research-page-001.jpg
Yehia, M. A., and M. O. H. A. M. E. D. ABDEL-RAHEEM, "Modelling of igniting flammable fuels in small and large scale turbulent environment", 14th International Conference on Energy for a Clean Environment, Funchal, Madeira, Portugal, 8 September, 2019.
Yehia, A. F., M. Saleh, A. Taha, and H. El-Shishiny, "Measuring Eigenvalues’ Sensitivities via Kernel Canonical Correlation Analysis.", Conference: The 33th International Conference of the System Dynamics Society, Cambridge, Massachusetts, USA, July, 2015.
Yehia, M. A. A., Modelling of pulverised coal swirling flames in axi-symmetric furnaces., : Imperial College London (University of London), 1992. Abstract
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Yehia, R. S., "Multi-Function of a New Bioactive Secondary Metabolite Derived from Endophytic Fungus <i>Colletotrichum acutatum</i> of <i>Angelica sinensis</i>", Journal of Microbiology and Biotechnology, vol. 33, issue 6: The Korean Society for Microbiology and Biotechnology, pp. 806 - 822, 2023/06/. AbstractWebsite

In the current study we assessed a new crystallized compound, 5-(1-hydroxybutyl)-4-methoxy-3-methyl-2H-pyran-2-one (C-HMMP), from the endophytic fungus Colletotrichum acutatum residing in the medicinal plant Angelica sinensis for its in vitro antimicrobial, antibiofilm, antioxidant, antimalarial, and anti-proliferative properties. The promising compound was identified as C-HMMP through antimicrobial-guided fraction. The structure of C-HMMP was unambiguously confirmed by 2D NMR and HIRS spectroscopic analysis. Antimicrobial property testing of C-HMMP showed it to be effective against a variety of pathogenic bacteria and fungi with MICs ranging from 3.9 to 31.25 μg/ml. The compound displayed excellent antibiofilm activity against C. albicans, S. aureus, and K. pneumonia. Furthermore, the antimalarial and radical scavenging activities of C-HMMP were clearly dosede-pendent, with IC50 values of 0.15 and 131.2 μg/ml. The anti-proliferative activity of C-HMMP against the HepG-2, HeLa, and MCF-7 cell lines in vitro was investigated by MTT assay, revealing notable anti-proliferative activity with IC50 values of 114.1, 90, and 133.6 μg/ml, respectively. Moreover, C-HMMP successfully targets topoisomerase I and demonstrated beneficial anti-mutagenicity in the Ames test against the reactive carcinogenic mutagen, 2-aminofluorene (2-AF). Finally, the compound inhibited the activity of α-glucosidase and α-amylase with IC50 values of 144.7 and 118.6 μg/ml, respectively. To the best of our knowledge, the identified compound C-HMMP was obtained for the first time from C. acutatum of A. sinensis, and this study demonstrated that C-HMMP has relevant biological significance and could provide better therapeutic targets against disease.

Yehia, M. A., and M. A. Abdel-Raheem, "Modelling of flammable fuels in small and large scale turbulent environments", FUEL, vol. 266, Submitted.
Yehia, M. A., and M. O. H. A. M. E. D. ABDEL-RAHEEM, "Modelling of igniting flammable fuels in small and large scale turbulent environment", 14th International Conference on Energy for a Clean Environment, Funchal, Madeira, Portugal, 8 September, 2019.
Yehia, A. M., H. T. Elbalkiny, S. 'aM. Riad, and Y. S. Elsaharty, "Monitoring and optimization of diclofenac removal by adsorption technique using in-line potentiometric analyzer", Microchemical Journal , vol. 148, pp. 521-530, 2019. 7.pdf
YM, E. S., "Mini-trabeculotomy in paediatric glaucoma", World Glaucoma Conference, Vancouver, 2013.
Yosri, A., S. Dickson-Anderson, and W. El-Dakhakhni, "A Modified Time Domain Random Walk Approach for Simulating Colloid Behavior in Fractures: Method Development and Verification", Water Resources Research, vol. 56, issue 7, pp. e2020WR027599, 2020.
Younan, A. A., and A. El-Shafei, "Model calibration of anisotropic rotordynamic systems with speed-dependent parameters", Journal of Engineering for Gas Turbines and Power, vol. 130, pp. 042502, 2008. Abstract
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Younes, N. F., A. E. - H. I. El Assasy, and A. I. A. Makhlouf, "Microenvironmental pH-modified Amisulpride-Labrasol matrix tablets: development, optimization and in vivo pharmacokinetic study.", Drug delivery and translational research, vol. 11, issue 1, pp. 103-117, 2021. Abstract

Amisulpride (AMS) is atypical antipsychotic with a weak basic nature (pKa 9.37), which results in low solubility in the high pH of the intestine. It is also recognized as a substrate of P-glycoprotein efflux pump. Both factors lead to its low oral bioavailability (48%). The daily dose of AMS is between 200 and 1200 mg to be taken in divided doses which compromise patient compliance. Therefore, controlled release formulation of AMS is of clinical significance. AMS was formulated into matrix tablets containing Labrasol, P-glycoprotein efflux inhibitor, and a penetration enhancer, using direct compression technique. The tablets were prepared according to 2·4 factorial design using two polymers, namely, HPMC and Carbopol 934 at four concentrations (20%, 30%, 40%, 50%). Percentage AMS released after 2 h (Q%) and 8 h (Q%) were chosen as dependent variables. Two acidic pH modifiers (fumaric acid and tartaric acid) at two levels (15% and 30%) were incorporated in the tablet according to 2 factorial design. All formulae with acidic pH modifier had similarity factor (f) ≥ 50 proving the pH independent release of AMS. The pharmacokinetic study in rabbits revealed 30% enhancement of the oral absorption AMS imparted by the pH-modified matrix tablet containing Labrasol. Graphical abstract.

Younes, N. F., A. E. - H. I. El Assasy, and A. I. A. Makhlouf, "Microenvironmental pH-modified Amisulpride-Labrasol matrix tablets: development, optimization and in vivo pharmacokinetic study.", Drug delivery and translational research, 2020. Abstract

Amisulpride (AMS) is atypical antipsychotic with a weak basic nature (pKa 9.37), which results in low solubility in the high pH of the intestine. It is also recognized as a substrate of P-glycoprotein efflux pump. Both factors lead to its low oral bioavailability (48%). The daily dose of AMS is between 200 and 1200 mg to be taken in divided doses which compromise patient compliance. Therefore, controlled release formulation of AMS is of clinical significance. AMS was formulated into matrix tablets containing Labrasol, P-glycoprotein efflux inhibitor, and a penetration enhancer, using direct compression technique. The tablets were prepared according to 2·4 factorial design using two polymers, namely, HPMC and Carbopol 934 at four concentrations (20%, 30%, 40%, 50%). Percentage AMS released after 2 h (Q%) and 8 h (Q%) were chosen as dependent variables. Two acidic pH modifiers (fumaric acid and tartaric acid) at two levels (15% and 30%) were incorporated in the tablet according to 2 factorial design. All formulae with acidic pH modifier had similarity factor (f) ≥ 50 proving the pH independent release of AMS. The pharmacokinetic study in rabbits revealed 30% enhancement of the oral absorption AMS imparted by the pH-modified matrix tablet containing Labrasol. Graphical abstract.

Younes, A. A., N. Zohdy, H. Aboulfadl, and R. Fathy, "Microbial biopesticides affected age-stage life table of the tomato leaf miner, Tuta absoluta (Lepidoptera – Gelechiidae)", Egyptian Journal of Biological Pest Control, vol. 28, issue 10, pp. 1-8, 2018. microbial_biopesticides_......pdf
Youness, E. R., H. F. Aly, H. T. El-Bassyouni, A. M. S. Tosson, M. M. Eid, O. M. Eid, A. El-Kotoury, and S. M. El-Daly, "Micronucleus assay and pro-oxidant status of patients with known chromosomal aneuploidy", Der Pharma Chemica, vol. 8, issue 13, pp. 158-164, 2016.
Youness, R. A., R. A. Assal, S. M. Ezzat, M. Z. Gad, and A. A. Motaal, "A methoxylated quercetin glycoside harnesses HCC tumor progression in a TP53/miR-15/miR-16 dependent manner", Natural Product Research, vol. 1, issue 1, pp. 1-7, 2018.
Younis, A. S. M., A. M. M. Al-Naggar, B. A. Bakry, and S. M. A. Nassar, "Maximizing Maize Grain, Protein, Oil and Starch Yields by Using High Plant Density and Stress Tolerant Genotype", Asian Journal of Plant Sciences, vol. 20, issue 1, pp. 91-101, 2021. maximizing_maize_grain_2.pdf
Younis, I. Y., A. R. Khattab, N. M. Selim, M. Sobeh, S. S. ElHawary, and M. E. H. Bishbishy, "Metabolomics‑based profiling of 4 avocado varieties using HPLC–MS/ MS and GC/MS and evaluation of their antidiabetic activity", Scientific Reports, vol. 12, 2022. avocado_seeds-_manuscript.pdf
Younis, S.M., A. M. M. Al-Naggar, B. A. Bakry, and S. M. A. Nassar, "Maximizing Maize Grain, Protein, Oil and Starch Yields by Using High Plant Density and Stress Tolerant Genotype", Asian Journal of Plant Sciences, vol. 20 , issue 1, pp. 91-101, 2021. maximizing_maize_grain_2.pdf
Younis, M., G. S. Essawy, H. I. Abass, S. A. Essawy, and A. M. Otteifa, "Metabolic profile testing of postpartum Egyptian buffaloes. B: Plasma macro- and micro-elements. ", Buffalo Journal , 1995.
Yousef, T. A., and N. F. Osman, "Measuring Through Plane Strain in Brain Using Strain-Encoding (SENC) MRI", Proc. Intl. Soc. Mag. Reson. Med, vol. 15, pp. 3316, 2007. Abstract
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Yousef, S., and E. M. Raey, "Major Solar Episodes Reconstructed Using Records Of the river Nile , Tree-Ring Indices and Sunspot", De L’ Institut D’ Egypte., vol. Tomes LXXIV, pp. 76-108, 1994. nile_arab_epoch_pp_77-941.docsecond_part_95-108.doc
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