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Saleh, D. 'aA., S. Amr, I. A. Jillson, J. H. -yu Wang, W. A. Khairy, and C. A. Loffredo, "Knowledge and perceptions of hepatitis C infection and pesticides use in two rural villages in Egypt.", BMC public health, vol. 14, pp. 501, 2014. Abstract

BACKGROUND: Hepatocellular carcinoma (HCC), one of the most fatal types of malignancy, is increasing worldwide, and particularly in Egypt where there is a confluence of its contributing factors, including high prevalence of hepatitis C virus (HCV) infection, widespread use of pesticides, and diets that are contaminated by aflatoxin B1 (AFB1) in rural areas. We investigated knowledge, attitudes, and prevention practices related to HCV infection and pesticides use in rural Egypt, where over half of the population resides and agriculture is the predominant occupation.

METHODS: From two rural villages we recruited 67 residents aged 18-80 years, who completed a 40-item survey that included questions about demographics, knowledge of and protective measures relevant to pesticides use in the home and in agriculture, awareness and perceptions of HCV infection and its treatment and prevention.

RESULTS: Among the 67 study participants, gender distribution was equal, the mean age was 47.2, and one third never attended school. More than 50% reported using pesticides at home, but fewer reported having some knowledge about its health effects. Twelve participants were agricultural workers, and 11 of them applied pesticides in the field and knew about their toxicity; however only one person was correctly using the appropriate protective equipment. Among all the participants, 52 did not know what causes HCV infection, and 42 of those who knew it was a virus mentioned incorrect modes of transmission; and 30 did not know the disease manifestations.

CONCLUSION: In rural Egypt, there is a significant lack of knowledge of HCV infection and its transmission mode and limited use of protective measures against pesticides despite familiarity with these chemicals.

Saleh, D. 'aA., S. Amr, I. A. Jillson, J. H. -yu Wang, W. A. Khairy, and C. A. Loffredo, "Knowledge and perceptions of hepatitis C infection and pesticides use in two rural villages in Egypt.", BMC public health, vol. 14, pp. 501, 2014. Abstract

BACKGROUND: Hepatocellular carcinoma (HCC), one of the most fatal types of malignancy, is increasing worldwide, and particularly in Egypt where there is a confluence of its contributing factors, including high prevalence of hepatitis C virus (HCV) infection, widespread use of pesticides, and diets that are contaminated by aflatoxin B1 (AFB1) in rural areas. We investigated knowledge, attitudes, and prevention practices related to HCV infection and pesticides use in rural Egypt, where over half of the population resides and agriculture is the predominant occupation.

METHODS: From two rural villages we recruited 67 residents aged 18-80 years, who completed a 40-item survey that included questions about demographics, knowledge of and protective measures relevant to pesticides use in the home and in agriculture, awareness and perceptions of HCV infection and its treatment and prevention.

RESULTS: Among the 67 study participants, gender distribution was equal, the mean age was 47.2, and one third never attended school. More than 50% reported using pesticides at home, but fewer reported having some knowledge about its health effects. Twelve participants were agricultural workers, and 11 of them applied pesticides in the field and knew about their toxicity; however only one person was correctly using the appropriate protective equipment. Among all the participants, 52 did not know what causes HCV infection, and 42 of those who knew it was a virus mentioned incorrect modes of transmission; and 30 did not know the disease manifestations.

CONCLUSION: In rural Egypt, there is a significant lack of knowledge of HCV infection and its transmission mode and limited use of protective measures against pesticides despite familiarity with these chemicals.

MANAL M. EL-SAWY, G. E. H. A. N. M. ISMAIL, Heba Magdy, and G. E. H. A. N. A. EL-SAMMAN, "Knowledge and Home Practices of Caregivers Having Children with Leukemia Attending National Cancer Institute Cairo University", The medical journal of cairo universty, vol. 81, pp. 601-608, 2013. abstract_manal.pdfknowledge_and_home_practices_of_caregivers.pdf
El-Mously, S., H. Hamdy, A. Abdel-Monem, A. M. Abdelalim, E. N. Sherbiny, S. M. Ahmed, R. R. Moustafa, H. Samir, T. H. Emara, A. H. Ghaffar, et al., "Knowledge and attitudes towards stroke among workers in three university hospitals in Egypt", World Congerss of Neuology, Vienna- Austria, 10/2013.
Abdelalim, A., H. Shehata, N. E. Sherbiny, and S. Ahmed, "Knowledge and attitude towards stroke among workers in Cairo University Hospitals", The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, vol. 53, issue 1, pp. 54 - 59, 2016/1/1. AbstractWebsite

BackgroundStroke is a major cause of mortality and morbidity worldwide. Poor knowledge of stroke risk factors, symptoms and appropriate response to stroke are possible causes of poor outcome.
Objective
The aim of this study was to evaluate the knowledge and attitude towards different aspects of stroke in a sample of Cairo University Hospitals' workers.
Patients and methods
A structured self-administered questionnaire was administered by 111 workers who were classified into clinical workers (physicians, house officers, nurses, laboratory technician and pharmacists) and nonclinical workers (administrative, sanitary and security workers).
Results
Out of 111 participants, 92 completed the questionnaire. Most participants had heard of stroke (91.3%), mostly through encountering a family member with a stroke rather than through mass media (10.9%). Hypertension was the most common identified stroke risk factor (66.3%). Clinical workers were more likely to identify risk factors. The most common identified stroke symptoms were slurring of speech (38.5%) and elevated blood pressure (38.5%). Clinical workers were more likely to identify symptoms such as slurring of speech (P = 0.042) and altered state of consciousness (P < 0.001). The most frequent response to an attack of stroke was transferring the patients to a hospital (59.8%).
Conclusion
Knowledge and perception of stroke in Cairo University Hospitals' workers appear to be poor, especially among nonclinical workers. Planning educational programs for raising the level of knowledge and awareness of stroke, both on the level of hospital workers and on the public level, is important to improve stroke management and outcome.

Hussein, A. M., N. M. Milad, M. D. Sarhan, and A. S. AbdelWahed, KNOTS VERSUS ENDOCLIPS FOR STUMP CLOSURE IN LAPAROSCOPIC APPENDECTOMY, , 2016. lap_appndx.pdf
RM, M., E. - S. NN, and A. MA, "The Knoevenagel reactions of pregnenolone with cyanomethylene reagents: synthesis of thiophene, thieno[2,3-b]pyridine, thieno[3,2-d]isoxazole derivatives of pregnenolone and their in vitro cytotoxicity towards tumor and normal cell lines.", Steroids, vol. 78, issue 12-13, pp. 1209–1219, 2013. Abstract

The reaction of pregnenolone with either 2-aminoprop-1-ene-1,1,3-tricarbonitrile or 3-oxo-3-phenylpropanenitrile gave the Knoevenagel condensation products 3 and 6, respectively. Separation of the E and Z isomeric compounds of 3 and 6 together with their structure elucidation were carried out. Some chemical transformations of the latter products were carried out and the cytotoxicity of the newly obtained products was evaluated against some cancer cell lines and a human normal cell line. The results indicated that compounds 15, 17a, 18 and 20e among the tested compounds showed the highest cytotoxicity against the cancer cell lines.

Mottaleb, S. A., A. Rodriguez-Navarro, and R. Haro, "Knockouts of Physcomitrella patens CHX1 and CHX2 Transporters Reveal High Complexity of Potassium Homeostasis", Plant and Cell Physiology, vol. 54, issue 9, pp. 1455–1468, 2013.
Elgohary, D. H., T. F. Khalifa, M. M. Salem, N. M. Aly, E. Hassan, and A. A. Shamaa, "Knitted cardiac mesh to support left ventricular hypertrophy: an in vivo experimental study: “Supporting left ventricular hypertrophy using cardiac support mesh”", Research Journal of Textile and Apparel, 2021. AbstractWebsite
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Aboeleneen, A. M., M. S. Abdrabo, and A. Darwesh, "Knee Joint Reposition Accuracy among ChronicLow Back Pain Patients and Healthy Subjects", Middle-East Journal of Scientific Research , vol. 23, issue 9, pp. 2213-2218, 2015.
Aboeleneen, A. M., and A. Darwesh, "KNEE JOINT PROPRIOCEPTION AND QUADRICEPS MUSCLE STRENGTH AMONG DIABETIC AND NON DIABETIC SUBJECTS", International journal of physiotherapy, vol. 3, issue 6, pp. 687-692, 2016. 13ijphy533_2016.pdf
Aboeleneen, A. M., and A. Darwesh, "KNEE JOINT PROPRIOCEPTION AND QUADRICEPS MUSCLE STRENGTH AMONG DIABETIC AND NON DIABETIC SUBJECTS", International journal of physiotherapy, vol. 3, issue 6, pp. 687-692, 2016. 13ijphy533_2016.pdf
Emad, Y., Y. Ragab, T. Gheita, A. Anbar, H. Kamal, A. Saad, H. Darweesh, N. Elshaarawy, A. Azab, A. Ismail, et al., "Knee Enthesitis Working Group. Knee enthesitis and synovitis on magnetic resonance imaging in patients with psoriasis without arthritic symptoms.", J Rheumatol. 2012 Oct;39(10):, vol. 39, issue 10, pp. 1979-1986. doi: 10.3899/jrheum.120301. , 2012. Website
, "Knee enthesitis and synovitis on magnetic resonance imaging in patients with psoriasis without arthritic symptoms.", J Rheumatol., vol. Oct;39(10):1979-86. doi: 10.3899/jrheum.120301. Epub 2012 Aug 1., 2012.
Laura Cif, K. E. Barwick, J. - P. Lin, M. Sa, L. Abela, D. Demailly, S. Malhotra, Wui K Chong, D. Steel, and L. Selim, "KMT2B-related disorders: expansion of the phenotypic spectrum and long-term efficacy of deep brain stimulation", brain, vol. 143, issue 11, pp. 3242-3261, 2020.
HAMDY, M. O. N. A., I. Shaheen, H. S. E. Din, B. Ali, and O. A. E. Dayem, "Klotho Level as a Marker of Low Bone Mineral Density in Egyptian Sickle Cell Disease Patients", Journal of Pediatric Hematology/Oncology (JPHO), 2021.
Elghoroury, E. A., F. I. Fadel, M. F. Elshamaa, D. Kandil, D. M. Salah, M. M. El-Sonbaty, H. Farouk, M. Raafat, and S. Nasr, "Klotho G-395A gene polymorphism: impact on progression of end-stage renal disease and development of cardiovascular complications in children on dialysis.", Pediatric nephrology (Berlin, Germany), vol. 33, issue 6, pp. 1019-1027, 2018 Jun. Abstract

BACKGROUND: Klotho G-395-A gene polymorphism may impact children with end-stage renal disease (ESRD). We investigated the relevance of Klotho G-395-A on ESRD development and progression, and its relationship with evolution of cardiovascular complications in pediatric dialysis patients.

METHODS: Fifty-five children with chronic kidney disease (CKD) and seventy healthy children were genotyped for Klotho G-395A.

RESULTS: Incidence of GA/AA genotypes and A allele were higher in ESRD patients compared with controls (54.5 vs. 7.1%, P < 0.001; 30.9 vs. 13.6%, P = 0.001, respectively). Also, children with GA/AA genotypes were 15.6 times more likely to develop ESRD than with GG genotype (95% CI 5.4-44.7, P < 0.001). A allele carriers have 2.8 times higher risk of developing ESRD than those with G allele (95% CI 1.5-5.35, P = 0.001). Also, the A allele could be considered a predictor of cardiovascular disease (CVD), as carriers have 161 times higher risk of cardiovascular complications than non-carriers (95% CI 21-1233, P < 0.001). All ESRD patients with CVD presented with left ventricular hypertrophy (LVH) and the frequency of A allele was significantly higher among ESRD children with LVH, whereas G allele frequency was significantly higher among ESRD children without LVH.

CONCLUSIONS: The A allele of the G-395A Klotho gene polymorphism shows a significantly higher frequency among children with CKD and those with CVD and LVH. This mutant allele could be used as a risk marker for the development of ESRD as well as a predictor of CVD in these children.

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