Publications

Export 2876 results:
Sort by: [ Author  (Desc)] Title Type Year
A B C D E F G [H] I J K L M N O P Q R S T U V W X Y Z   [Show ALL]
V
van der Ven, A. T., B. Kobbe, S. Kohl, S. Shril, H. - M. Pogoda, T. Imhof, H. Ityel, A. Vivante, J. Chen, D. - Y. Hwang, et al., "A homozygous missense variant in VWA2, encoding an interactor of the Fraser-complex, in a patient with vesicoureteral reflux.", PloS one, vol. 13, issue 1, pp. e0191224, 2018. Abstract

Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause (40-50%) of chronic kidney disease (CKD) in children. About 40 monogenic causes of CAKUT have so far been discovered. To date less than 20% of CAKUT cases can be explained by mutations in these 40 genes. To identify additional monogenic causes of CAKUT, we performed whole exome sequencing (WES) and homozygosity mapping (HM) in a patient with CAKUT from Indian origin and consanguineous descent. We identified a homozygous missense mutation (c.1336C>T, p.Arg446Cys) in the gene Von Willebrand factor A domain containing 2 (VWA2). With immunohistochemistry studies on kidneys of newborn (P1) mice, we show that Vwa2 and Fraser extracellular matrix complex subunit 1 (Fras1) co-localize in the nephrogenic zone of the renal cortex. We identified a pronounced expression of Vwa2 in the basement membrane of the ureteric bud (UB) and derivatives of the metanephric mesenchyme (MM). By applying in vitro assays, we demonstrate that the Arg446Cys mutation decreases translocation of monomeric VWA2 protein and increases translocation of aggregated VWA2 protein into the extracellular space. This is potentially due to the additional, unpaired cysteine residue in the mutated protein that is used for intermolecular disulfide bond formation. VWA2 is a known, direct interactor of FRAS1 of the Fraser-Complex (FC). FC-encoding genes and interacting proteins have previously been implicated in the pathogenesis of syndromic and/or isolated CAKUT phenotypes in humans. VWA2 therefore constitutes a very strong candidate in the search for novel CAKUT-causing genes. Our results from in vitro experiments indicate a dose-dependent neomorphic effect of the Arg446Cys homozygous mutation in VWA2.

Valder, O.; S.;A. V. A. C., A. C. V. H. H. h i E. Agosin f, A. Altundag g, and G. G. K. M. N. R. l m C. Cornejo j, G. Fishman k, "Hedonic perception of odors in children aged 5–8 years is similar across 18 countries: Preliminary data", International Journal of Pediatric Otorhinolaryngology, vol. 157, issue June 2022, 2022.
Valdenaire, A., A. E. Giba, M. Stoffel, X. Devaux, L. Foussat, J. - M. Poumirol, C. Bonafos, S. Guehairia, R. Demoulin, E. Talbot, et al., "Heavily Doped Si Nanocrystals Formed in P-(SiO/SiO2) Multilayers: A Promising Route for Si-Based Infrared Plasmonics", ACS Applied Nano MaterialsACS Applied Nano Materials, vol. 6, issue 5: American Chemical Society, pp. 3312 - 3320, 2023. AbstractWebsite
n/a
U
Uversky, V. N., F. Elrashdy, A. Aljadawi, and E. M. Redwan, "Household pets and SARS-CoV2 transmissibility in the light of the ACE2 intrinsic disorder status.", Journal of biomolecular structure & dynamics, pp. 1-4, 2020.
Usama Salem, Christine O. Menias, Akram Shaaban, Priya R. Bhosale, A. Youssef, and K. M. Elsayes, "Hematopoietic tumors of the female genital system: imaging features with pathologic correlation", Abdominal Imaging , 2014.
undefined, E. A. A. El-Shaarawy, A. F. El-Domairy, and M. OSMAN, "Histological and Immunohistochemical study of the hepatic changes following Cisplatin administration in adult male albino rat and possible protective role of L-carnitine.", Egyptian journal of Anatomy, vol. 37, no. 1, pp. 159–175, 2014. Abstract

Background: Cisplatin is one of the most effective chemotherapeutic agents used in the treatment of several human cancers, but its usefulness is limited by its hepatotoxicity which sometimes requires discontinuation of the treatment. A number of drugs were used to ameliorate the injurious effect of cisplatin on liver. One of the most important of these drugs is L-carnitine.
Aim of the work: The present study was designed to investigate the different pathological effects and the extent of apoptosis induced by cisplatin in liver tissue, and the potential protective effect of L-carnitine against it. This in turn, may affect the treatment regime of cisplatin.
Material and methods: Eighty adult male Wistar albino rats were divided into 5 groups. Group I (control group) contained 20 rats, whereas each of the other groups contained 15 rats. These experimental groups were cisplatin group (group II) which received saline injection 5 days prior and after a single cisplatin injection (7 mg/kg IP), cisplatin recovery group (group III) which received saline 5 days before and 21 days after a single cisplatin injection of the same dose. Cisplatin and L-carnitine group (group IV) and cisplatin and L-carnitine recovery group (group V) corresponded to groups II and III respectively in their time design, but L-carnitine was used instead of saline. Liver specimens were subjected to hematoxylin and eosin, Masson trichrome, silver staining as well as immunohistochemical Caspase-3 examination and measurements utilizing image analysis technique.
Results: The histological results revealed the injurious effect of cisplatin on the liver. The groups treated with cisplatin alone showed degeneration featured by cytoplasmic vacuolization, ghost figures, karyolysis, pyknosis, mononuclear cellular infiltration, hypochromatic nuclei, multiple nucleoli, intranuclear vacuolization, portal congestion and oedema and necrotic cells. The lesions affected mainly the pericentral and midzonal areas. The groups treated with cisplatin and L-carnitine showed mild or no affection, with preservation of normal hepatic architecture. The central vein diameter, the stromal framework disruption and apoptotic cells increased in the cisplatin groups, but it was much less affected in the cisplatin and L-carnitine groups. The recovery groups showed statistically higher values as regards the area percent of fibrous tissue, with partial privilege to the L-carnitine combined treatment
Conclusion: The present work revealed that L-carnitine provided an excellent protective factor against the damaging effects of cisplatin on the liver as regards general histological picture, stromal framework integrity, central vein diameter and apoptosis, but it partially protected the liver against fibrosis. The safeguarding effect of L-carnitine increased with its administration for a longer period before and after cisplatin.

undefined, H. M. Salem, and M. S. Abdel-latif, "The hypoglycemic effect of B-Pyridoxyl Carbinol (Ronicol)", Annals. Agric. Sci. Moshtohor , vol. 20, pp. 93, 1983.
T
Torky, A. A., and Y. F. Rashed, "High-performance practical stiffness analysis of high-rise buildings using superfloor elements", Journal of Computational Design and Engineering, vol. 7, no. 2: Oxford University Press, pp. 211–227, 2020. Abstract
n/a
Tolba, M. F., W. S. Sayed, A. G. Radwan, S. K. Abd-El-Hafiz, and A. M. Soliman, "Hardware Speech Encryption Using a Chaotic Generator, Dynamic Shift and Bit Permutation", 2018 30th International Conference on Microelectronics (ICM): IEEE, pp. 100–103, 2018. Abstract
n/a
Tolba, M. F., W. S. Sayed, A. G. Radwan, S. K. Abd-El-Hafiz, and A. M. Soliman, "Hardware speech encryption using a chaotic generator, dynamic shift and bit permutation", International Conference on Microelectronics (ICM-2018), Sousse, Tunisia, December, 2018.
TJ, V., H. A, N. - E. NA, G. - R. T, E. K, Ackermann H, Bechstein WO, and N. NN, "High-frequency versus low-frequency microwave ablation in malignant liver tumours: evaluation of local tumour control and survival", INTERNATIONAL JOURNAL OF HYPERTHERMIA, vol. Dec;32, issue 8, pp. 868-875, 2016.
Thabet, A. A., A. M. Elsodany, K. H. Battecha, M. A. Alshehri, and B. Refaat, "High-intensity laser therapy versus pulsed electromagnetic field in the treatment of primary dysmenorrhea", The Journal of Physical Therapy Science, vol. 29, pp. 1742-1748, 2017. high-intensity_laser_therapy_versus_pulsed_electromagnetic_field_in_the_treatment_of_primary_dysmenorrhea.pdf
Thabet, A. A. E. - M., A. M. Elsodany, K. H. Battecha, M. A. Alshehri, and B. Refaat, "High-intensity laser therapy versus pulsed electromagnetic field in the treatment of primary dysmenorrhea", The Journal of Physical Therapy Science, vol. 29, pp. 1742-48, 2017. high-intensity_laser_therapy_versus_pulsed_electromagnetic_field_in_the_treatment_of_primary_dysmenorrhea.pdf
Thabet, A. A. E. - M., A. M. Elsodany, K. H. Battecha, M. A. Alshehri, and B. Refaat, "High-intensity laser therapy versus pulsed electromagnetic field in the treatment of primary dysmenorrhea.", Journal of physical therapy science, vol. 29, issue 10, pp. 1742-1748, 2017 Oct. Abstract

[Purpose] To determine the efficacy of high intensity laser therapy (HILT) versus pulsed electromagnetic field (PEMF) in the treatment of primary dysmenorrhea. [Subjects and Methods] This was a randomized clinical trial that included 52 girls diagnosed with primary dysmenorrhea and who were assigned randomly into two groups of equal numbers. The treatment was three sessions every cycle for three consecutive cycles where group (A) included those participants treated with HILT 15 min/session and group (B) those who were treated with PEMF 30 min/session. All patients were evaluated before starting the treatment as well as after the end of treatment by present pain intensity scale and the prostaglandin level in blood and pain relief scale at the end of treatment for both groups. [Results] The results showed a significant decrease in the severity of pain, statistically significant decrease in prostaglandin level in blood, and a statistically significant pain alleviation in both groups. With comparison between both groups there was a statistically significant decrease in the severity of pain, significant decrease in the blood levels of PGF2α, in group (A) than group (B). [Conclusion] Both HILT and PEMF are effective in the treatment of primary dysmenorrhea with HILT being superior to PEMF.

Temerak, M. S., and S. ElSaadany, "How do customers’ perceptions of the firm and other customers predict their proactive and reactive helping behavior?", Academy of Marketing, Stirling University , British Academy of Marketing, 2018.
Temerak, M. S., and DahliaEl-Manstrly, "he influence of goal attainment and switching costs on customers’ staying intentions", Journal of Retailing and Consumer Services, vol. 51, pp. 51-61, 2019.
Teleb, M. M. A., H. M. Hassaneen, I. A. Abdelhamid, and F. M. Saleh, "Hantzsch-like synthesis of the 10 b-azachrysenes, spirocyclic oxindole of 10 b-azachrysene and 10 a-azaphenanthrene utilizing 2-(6, 7-dimethoxy-3, 4-dihydroisoquinolin-1-yl) acetonitrile as a precursor", Synthetic Communications, vol. 51, issue 4: Taylor & Francis, pp. 553-562, 2021. Abstract
n/a
Teleb, M. M. A., H. M. Hassaneen, I. A. Abdelhamid, and F. M. Saleh, "Hantzsch-like synthesis of the 10 b-azachrysenes, spirocyclic oxindole of 10 b-azachrysene and 10 a-azaphenanthrene utilizing 2-(6, 7-dimethoxy-3, 4-dihydroisoquinolin-1-yl) acetonitrile as a precursor", Synthetic Communications, vol. 51, issue 4: Taylor & Francis, pp. 553-562, 2021. Abstract
n/a
Teleb, M. M. A., H. M. Hassaneen, I. A. Abdelhamid, and F. M. Saleh, "Hantzsch-like synthesis of the 10 b-azachrysenes, spirocyclic oxindole of 10 b-azachrysene and 10 a-azaphenanthrene utilizing 2-(6, 7-dimethoxy-3, 4-dihydroisoquinolin-1-yl) acetonitrile as a precursor", Synthetic Communications, vol. 51, issue 4: Taylor & Francis, pp. 553-562, 2021. Abstract
n/a
Teleb, M. M. A., H. M. Hassaneen, I. A. Abdelhamid, and F. M. Saleh, "Hantzsch-like synthesis of the 10 b-azachrysenes, spirocyclic oxindole of 10 b-azachrysene and 10 a-azaphenanthrene utilizing 2-(6, 7-dimethoxy-3, 4-dihydroisoquinolin-1-yl) acetonitrile as a precursor", Synthetic Communications, vol. 51, issue 4: Taylor & Francis, pp. 553-562, 2021. Abstract
n/a
Teleb, M. M. A., H. M. Hassaneen, I. A. Abdelhamid, and F. M. Saleh, "Hantzsch-like synthesis of the 10 b-azachrysenes, spirocyclic oxindole of 10 b-azachrysene and 10 a-azaphenanthrene utilizing 2-(6, 7-dimethoxy-3, 4-dihydroisoquinolin-1-yl) acetonitrile as a precursor", Synthetic Communications, vol. 51, issue 4: Taylor & Francis, pp. 553-562, 2021. Abstract
n/a
Tayie, M. S., "The Hydropolitics of the Nile River Basin", The Nile River: Springer - Springer International Publishing, 2017.
Tourism