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Salem, M. A., and N. G. Gomaa, "Hypoallergic Tape: A Tool for Prevention of Peri-Incision Skin Injury after Hip Surgery", World Journal of Medical Sciences, vol. 5, issue 3, pp. 74-80, 2010. Abstract
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Assem, M., M. Amin, O. khalaf ALLAH, A. Hussien, A. Saif, and S. Mousa, "Hypoadiponectinemia as a marker of increased cardiovascular risk in patients with non-alcoholic fatty liver disease: correlation with albumin/creatinine ratio.", Archives of endocrinology and metabolism, 2020. Abstract

Objective: We assessed plasma adiponectin and its correlation with carotid intima-media-thickness (CIMT), as a marker of atherosclerosis, and urine albumin/creatinine ratio (ACR) in patients with non-alcoholic fatty liver disease (NAFLD).

Methods: The study included 100 Egyptian subjects (50 patients with NAFLD with no history of diabetes or hypertension and 50 age and sex-matched normal healthy control subjects). Urine albumin/creatinine ratio (ACR) was assessed in all participants and fasting plasma adiponectin was measured using ELISA technique. Ultrasonography was used to diagnose NAFLD. CIMT was assessed using high-resolution Doppler ultrasonography.

Results: Mild albuminuria was detected in patients with NAFLD (mean urine ACR = 42 ± 30 mg/g). Plasma adiponectin was significantly lower and urine ACR and CIMT significantly higher in patients with NAFLD as compared with the control group (P < 0.001 for all). A significant negative correlation was found between plasma adiponectin and both urine ACR and CIMT in patients with NAFLD (P < 0.001 and < 0.05 respectively). A significant positive correlation was also found between CIMT and urine ACR in those patients (P < 0.05). Plasma adiponectin and urine ACR were independent determinants of CIMT in patients with NAFLD (P < 0.01 and < 0.05 respectively).

Conclusion: Patients with NAFLD, without diabetes, have an increased risk of atherosclerosis and cardiovascular disease. Hypoadiponectinemia and low-grade albuminuria are important markers of that risk.

Assem, M., M. Amin, O. khalaf ALLAH, A. Hussien, A. Saif, and S. Mousa, "Hypoadiponectinemia as a marker of increased cardiovascular risk in patients with non-alcoholic fatty liver disease: correlation with albumin/creatinine ratio.", Archives of endocrinology and metabolism, 2020. Abstract

Objective: We assessed plasma adiponectin and its correlation with carotid intima-media-thickness (CIMT), as a marker of atherosclerosis, and urine albumin/creatinine ratio (ACR) in patients with non-alcoholic fatty liver disease (NAFLD).

Methods: The study included 100 Egyptian subjects (50 patients with NAFLD with no history of diabetes or hypertension and 50 age and sex-matched normal healthy control subjects). Urine albumin/creatinine ratio (ACR) was assessed in all participants and fasting plasma adiponectin was measured using ELISA technique. Ultrasonography was used to diagnose NAFLD. CIMT was assessed using high-resolution Doppler ultrasonography.

Results: Mild albuminuria was detected in patients with NAFLD (mean urine ACR = 42 ± 30 mg/g). Plasma adiponectin was significantly lower and urine ACR and CIMT significantly higher in patients with NAFLD as compared with the control group (P < 0.001 for all). A significant negative correlation was found between plasma adiponectin and both urine ACR and CIMT in patients with NAFLD (P < 0.001 and < 0.05 respectively). A significant positive correlation was also found between CIMT and urine ACR in those patients (P < 0.05). Plasma adiponectin and urine ACR were independent determinants of CIMT in patients with NAFLD (P < 0.01 and < 0.05 respectively).

Conclusion: Patients with NAFLD, without diabetes, have an increased risk of atherosclerosis and cardiovascular disease. Hypoadiponectinemia and low-grade albuminuria are important markers of that risk.

Shafik A, Shafik AA, S. E. - S. I. O., "The hypoactive corpora cavernosa with degenerative erectile dysfunction: a new syndrome", BMC Urology , 2006.
Khaled, A. - E. L. - S., "Hypnotic and general anaesthetic effects of Citrus aurantium L. oil on rats", 3rd Global Summit on Herbals & Traditional Medicine, Osaka, Japan, 18-20 October, pp. 8, 2017.
Fahim, E. - S., "Hypervitaminosis and monoamines in different CNS areas of albino rat. II- Effect of thiamine", J. Egypt. Ger. Soc. Zool., vol. 24 (A), pp. 49-68, 1997.
Fahim, E. - S., "Hypervitaminosis and monoamines in different CNS areas of albino rat I- Effect of pyridoxine", J. Egypt. Ger. Soc. Zool., vol. 24 (A): , pp. 17-34, 1997.
Mario, E., D. Hamza, and K. Abdel-Moein, "Hypervirulent Klebsiella pneumoniae among diarrheic farm animals: A serious public health concern", Comparative Immunology, Microbiology and Infectious Diseases, vol. 102, pp. 102077, 2023.
Abdel-Aziz, M., "Hypertrophied tonsils impair velopharyngeal function after palatoplasty", Laryngoscope . , vol. 122, issue 3, pp. 528-532, 2012. laryngoscope_1.pdf
SA, E. - S., S. ZS, and E. RI, "Hypertrophic cardiomyopathy: prognostic factors and survival analysis in 128 Egyptian patients", Cardiol Young, vol. 29, pp. 1-7, 2013.
El-Saiedi, S. A., Z. S. Seliem, and R. I. Esmail, "Hypertrophic cardiomyopathy: prognostic factors and survival analysis in 128 Egyptian patients", Cardiology in the Young, vol. 24, issue 4, pp. 702-708, 2014.
El-Kady, N. M., G. Esmat, E. H. Mahmoud, S. K. Darweesh, S. H. Mahmoud, and W. A. Elagawy, "Hypertonic saline-enhanced radiofrequency versus chemoembolization sequential radiofrequency in the treatment of large hepatocellular carcinoma", EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, vol. 25, no. 5, pp. 628-633, MAY, 2013. Abstract
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El-Kady, N. M., G. Esmat, E. H. Mahmoud, S. K. Darweesh, S. H. Mahmoud, and W. A. Elagawy, "Hypertonic saline-enhanced radiofrequency versus chemoembolization sequential radiofrequency in the treatment of large hepatocellular carcinoma", Eur J Gastroenterol Hepatol., vol. 25, issue 5, pp. 628-33, 2013. abstract.doc
EL Tayeb, M. A., N. El Sharnoubi, M. El Shenawi, and N. Abou El Ezz, "HYPERTONIC SALINE IN MANAGEMENT OF PEDIATRIC HEAD TRAUMA PATIENT. DOES IT MAKE A DIFFERENCE?", Scientific Journal Azhar University, vol. 29, issue 1, 2008.
Farahat, S. A., L. A. Rashed, A. M. Samir, and D. A. M. Hamid, "Hyperthyroidism among Galvanization Workers Due to Exposure to Zinc Fumes.", CEJOEM, vol. 13, issue (3-4), pp. 240-250, 2007.
SA, F., S. AM, A. - H. DM, and R. LA, "HYPERTHYROIDISM AMONG GALVANIZATION WORKERS DUE TO EXPOSURE TO ZINC FUMES ", Central European Journal of Occupational and Environmental Medicine, vol. 13, issue 3, pp. 240-249, 2007. hyperthyroidism_due_to_occupational_exposure_to_zinc_fumes.doc
Farahat, S. A., L. A. Rashed, A. M. Samir, and D. A. - H. Shaker, "HYPERTHYROIDISM AMONG GALVANIZATION WORKERS DUE TO EXPOSURE TO ZINC FUMES", Egyptian Journal of Occupational Medicine, vol. 13, issue 3, pp. 240–249, 2007. zinc_hyperthyroidism_ce7_3-04xx_1.pdf
Ahmed, M. M., M. T. Khayyal, and M. M. el-Merzabani, "Hyperthermic potentiation of cisplatin cytotoxicity on solid Ehrlich carcinoma.", Tumori, vol. 79, issue 4, pp. 268-72, 1993 Aug 31. Abstract

BACKGROUND: Hyperthermia produces marked effects on many biochemical parameters of tumor cells and has been reported to potentiate the effect of many drugs. We therefore evaluated the possible synergistic effect between hyperthermia and cisplatin against solid Ehrlich carcinoma. The study was based on the measurement of some biologic characteristics in tumor tissues, namely: DNA, RNA, and protein content and their rate of synthesis as parameters for nuclear damage; total lipids and cholesterol as parameters for membrane damage; acid-phosphatase and acid-ribonuclease as parameters for lysosomal damage; and tumor volume as a direct parameter for tumor growth.

METHODS: Treatment of solid Ehrlich carcinoma by hyperthermia at 43 degrees C for 30 min for 3 successive days produced a 41.5% decrease in tumor volume, as well as a significant decrease in nucleic acids, protein contents and their rate of synthesis, in total lipids and cholesterol, and in acid-phosphatase and acid-ribonuclease. Chemotherapeutic management of the tumor by 5 mg/kg x 3 of cisplatin alone showed a continuous increase in tumor volume but at a lower rate than that of the untreated control. However, when cisplatin was given 1 h prior to hyperthermia, the tumor volume was significantly decreased by 82.6%.

RESULTS: The effects observed on all the investigated parameter were intensified when cisplatin was combined with hyperthermia. The results obtained suggest that hyperthermia may enhance the penetration of cisplatin to its target site inside the tumor cells due to a membrane-damaging effect. The enhanced lethality of cisplatin on tumor cells may also be due to the inhibition of DNA repair processes by hyperthermia.

Ahmed, M. M., M. T. Khayyal, and M. M. el-Merzabani, "Hyperthermic potentiation of cisplatin cytotoxicity on solid Ehrlich carcinoma.", Tumori, vol. 79, issue 4, pp. 268-72, 1993 Aug 31. Abstract

BACKGROUND: Hyperthermia produces marked effects on many biochemical parameters of tumor cells and has been reported to potentiate the effect of many drugs. We therefore evaluated the possible synergistic effect between hyperthermia and cisplatin against solid Ehrlich carcinoma. The study was based on the measurement of some biologic characteristics in tumor tissues, namely: DNA, RNA, and protein content and their rate of synthesis as parameters for nuclear damage; total lipids and cholesterol as parameters for membrane damage; acid-phosphatase and acid-ribonuclease as parameters for lysosomal damage; and tumor volume as a direct parameter for tumor growth.

METHODS: Treatment of solid Ehrlich carcinoma by hyperthermia at 43 degrees C for 30 min for 3 successive days produced a 41.5% decrease in tumor volume, as well as a significant decrease in nucleic acids, protein contents and their rate of synthesis, in total lipids and cholesterol, and in acid-phosphatase and acid-ribonuclease. Chemotherapeutic management of the tumor by 5 mg/kg x 3 of cisplatin alone showed a continuous increase in tumor volume but at a lower rate than that of the untreated control. However, when cisplatin was given 1 h prior to hyperthermia, the tumor volume was significantly decreased by 82.6%.

RESULTS: The effects observed on all the investigated parameter were intensified when cisplatin was combined with hyperthermia. The results obtained suggest that hyperthermia may enhance the penetration of cisplatin to its target site inside the tumor cells due to a membrane-damaging effect. The enhanced lethality of cisplatin on tumor cells may also be due to the inhibition of DNA repair processes by hyperthermia.

Ahmed, M. M., M. T. Khayyal, and M. M. el-Merzabani, "Hyperthermic potentiation of cisplatin cytotoxicity on solid Ehrlich carcinoma.", Tumori, vol. 79, issue 4, pp. 268-72, 1993 Aug 31. Abstract

BACKGROUND: Hyperthermia produces marked effects on many biochemical parameters of tumor cells and has been reported to potentiate the effect of many drugs. We therefore evaluated the possible synergistic effect between hyperthermia and cisplatin against solid Ehrlich carcinoma. The study was based on the measurement of some biologic characteristics in tumor tissues, namely: DNA, RNA, and protein content and their rate of synthesis as parameters for nuclear damage; total lipids and cholesterol as parameters for membrane damage; acid-phosphatase and acid-ribonuclease as parameters for lysosomal damage; and tumor volume as a direct parameter for tumor growth.

METHODS: Treatment of solid Ehrlich carcinoma by hyperthermia at 43 degrees C for 30 min for 3 successive days produced a 41.5% decrease in tumor volume, as well as a significant decrease in nucleic acids, protein contents and their rate of synthesis, in total lipids and cholesterol, and in acid-phosphatase and acid-ribonuclease. Chemotherapeutic management of the tumor by 5 mg/kg x 3 of cisplatin alone showed a continuous increase in tumor volume but at a lower rate than that of the untreated control. However, when cisplatin was given 1 h prior to hyperthermia, the tumor volume was significantly decreased by 82.6%.

RESULTS: The effects observed on all the investigated parameter were intensified when cisplatin was combined with hyperthermia. The results obtained suggest that hyperthermia may enhance the penetration of cisplatin to its target site inside the tumor cells due to a membrane-damaging effect. The enhanced lethality of cisplatin on tumor cells may also be due to the inhibition of DNA repair processes by hyperthermia.

Amira, G., A. Morsi, I. S. Fayek, and O. Mansour, "hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy in recurrent platinum-sensitive ovarian cancer: NCI case control study", Asian pacific journal of cancer prevention, vol. 20, issue 2, pp. 621-627, 2019. AbstractWebsite

Objectives: To assess the efficacy of cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal
chemotherapy (HIPEC) in recurrent platinum-sensitive ovarian cancer patients in comparison with standard intravenous
chemotherapy in terms of progression free survival and overall survival. Methods: Retrospective case control study
matching 15 cases with 20 controls with at least 24 months of follow up. Results: The two groups were comparable
and well matched in all aspects. Median follow up was 36 months in cases and 38 months in controls. The PFS2
revealed a median of 6 months (range 2-14) in cases and 5 months (range 2-18) in controls. The median OS was 36
and 38 months in cases and controls respectively. No statistically significant difference between the cases and controls
were observed in progression free survival (PFS2) and overall survival OS (P-value, 0.350 and 0.711 respectively).
However, the PFS2 was in favor of cases and OS was in favor of controls without reaching significance. The percentage
of patients who survived 5 years or more was 20% in cases and 35% in controls. The only issue in favor of HIPEC
is the significant reduction in chemotherapeutic toxicity when given by the intraperitoneal way (P- value 0.003).
Conclusion: According to our study, CRS and HIPEC do not seem to have impact on OS and PFS in the setting of
recurrent platinum sensitive ovarian cancer. However, we recommend on going researches with much more refined
selection criteria and with larger sample size.

Allam, R. S. H. M., and B. M. Ali, "Hypertensive uveitis: an initial presentation for primary antiphospholipid syndrome", Delta Journal of Ophthalmology, vol. 18, issue 3, pp. 185-189, 2017.
Allam, R. S. H. M., and B. M. Ali, "Hypertensive uveitis: an initial presentation for primary antiphospholipid syndrome", Delta J Ophthalmol, vol. 18, issue 3, pp. 185-189, 2017.
Allam, R. S. H. M., and B. M. Ali, "Hypertensive uveitis: an initial presentation for primary antiphospholipid syndrome", Delta Journal of Ophthalmology, vol. 18, issue 3, pp. 185-189, 2017.
Elsharkawy, S. H., and F. A. Torad, "Hypertensive Cardiomyopathy as a Sequel to Hydronephrosis Induced by Transitional Cell Carcinoma.", Topics in companion animal medicine, vol. 45, pp. 100585, 2021. Abstract

A 10-year-old female Griffon dog was presented for evaluation due to a 5-month history of hematuria and systemic hypertension. Thoracic auscultation detected a grade II/VI left apical systolic murmur. Abdominal ultrasound revealed the presence of a heterogeneous mass at the trigonal area of the urinary bladder, extending to the left ureter cranially and caudally toward the bladder's neck. Marked left hydronephrosis and hydroureter were detected as well as mild right hydronephrosis. Cytological examination of urine sediment confirmed the presence of transitional cell carcinoma. Echocardiography disclosed marked left ventricular concentric hypertrophy, which likely developed as a consequence of systemic hypertension induced by the bilateral hydronephrosis due to bladder transitional cell carcinoma.

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