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2023
Hussien, E., O. Ismael, and H. Elkady, "Hybrid Deep Learning-Based Approach for Enhanced Multi-Label Emotion Classification", the Eleventh International Conference on Intelligent Computing and Information Systems, Egypt, October 2023.
Zobaa, A. M., H. E. Shady Abdel Aleem, and K. M. Hosam Youssef, "Hosting Capacity Enhancement of Harmonically Distorted Distribution Systems Using Multi-Objective Artificial Hummingbird Algorithm", 2023 24th International Middle East Power System Conference (MEPCON), Mansoura, Egypt, pp. 1-8, 21 December, 2023. Abstract

Adding inverter-based renewables to harmonically distorted distribution systems without proper planning may lead to power quality issues, harmonic overload, overvoltage, and overheating equipment problems. Thus, the hosting capacity of the system must be controlled and enhanced so that it does not exceed the threshold value, to prevent these problems. In this paper, the enhancement of the hosting capacity of a harmonically distorted distribution system is achieved by harmonic mitigation. A damped double-tuned filter (DDTF) is utilized to reach this goal while operating the system within its acceptable operating limits according to IEEE 519 standard, the Egyptian electricity distribution code, the system voltage limitations, the transmission line thermal capacity, and the permitted power factor threshold values. A newly developed multi-objective optimization technique, namely multi-objective artificial hummingbird optimization algorithm (MOAHA), is employed to design the DDTF to maximize harmonic-constrained hosting capacity (HCHC), minimize the system active power losses, and satisfy the pre-mentioned set of operational constraints. The results prove the superiority and effectiveness of the suggested HCHC enhancement technique.

Valdenaire, A., A. E. Giba, M. Stoffel, X. Devaux, L. Foussat, J. - M. Poumirol, C. Bonafos, S. Guehairia, R. Demoulin, E. Talbot, et al., "Heavily Doped Si Nanocrystals Formed in P-(SiO/SiO2) Multilayers: A Promising Route for Si-Based Infrared Plasmonics", ACS Applied Nano MaterialsACS Applied Nano Materials, vol. 6, issue 5: American Chemical Society, pp. 3312 - 3320, 2023. AbstractWebsite
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Hassan, N., N. Bückreiß, J. Efing, M. Schulz-Fincke, P. König, B. Greve, G. Bendas, and M. Götte, "The Heparan Sulfate Proteoglycan Syndecan-1 Triggers Breast Cancer Cell-Induced Coagulability by Induced Expression of Tissue Factor", Cells, vol. 12, issue 6, 2023. Abstract

Syndecan-1 (Sdc-1) upregulation is associated with poor prognosis in breast cancer. Sdc-1 knockdown results in reduced angiogenesis and the dysregulation of tissue factor (TF) pathway constituents. Here, we evaluate the regulatory mechanisms and functional consequences of the Sdc-1/TF-axis using Sdc-1 knockdown and overexpression approaches in MCF-7 and MDA-MB-231 breast cancer cells. Gene expression was analyzed by means of qPCR. Thrombin generation and cell migration were detected. Cell-cycle progression and apoptosis were investigated using flow cytometry. In MDA-MB-231 cells, IL6, IL8, VEGF, and IGFR-dependent signaling affected TF pathway expression depending on Sdc-1. Notably, Sdc-1 depletion and TF pathway inhibitor (TFPI) synergistically affected PTEN, MAPK, and STAT3 signaling. At the functional level, the antiproliferative and pro-apoptotic effects of TFPI depended on Sdc-1, whereas Sdc-1’s modulation of cell motility was not affected by TFPI. Sdc-1 overexpression in MCF-7 and MDA-MB-231 cells led to increased TF expression, inducing a procoagulative phenotype, as indicated by the activation of human platelets and increased thrombin formation. A novel understanding of the functional interplay between Sdc-1 and the TF pathway may be compatible with the classical co-receptor role of Sdc-1 in cytokine signaling. This opens up the possibility of a new functional understanding, with Sdc-1 fostering coagulation and platelet communication as the key to the hematogenous metastatic spread of breast cancer cells.

Hefnawy, M. A., S. S. Medany, R. M. El-Sherif, N. El-Bagoury, and S. A. Fadlallah, High-performance IN738 superalloy derived from turbine blade waste for efficient ethanol, ethylene glycol, and urea electrooxidation, : Springer, pp. 1 - 12, 2023. Abstract
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Yehia, R. S., Highlighting the potential for crude oil bioremediation of locally isolated Cunninghamella echinulata and Mucor circinelloides, , vol. 54, issue 3, pp. 1969 - 1981, 2023. AbstractWebsite

The current investigation was carried out to assess the potential of fungi isolated from polluted soil samples in Al Jubail, Saudi Arabia, to degrade crude oil. In a minimal salt medium with 1% crude oil as the carbon source, the growth potential of various fungal isolates was examined. Among twelve fungal isolates, YS-6 and YS-10, identified as Cunninghamella echinulata and Mucor circinelloides based on multiple sequence comparisons and phylogenetic analyses, were selected as having superior crude oil degrading abilities. To the best of our knowledge, the isolated species have never been detected in polluted soil samples in the eastern province of Saudi Arabia. YS-6 and YS-10 have shown their capacity to metabolize crude oil by removing 59.7 and 78.1% of crude oil, respectively. Interestingly, they succeeded in reducing the surface tension to 41.2 and 35.9 mN/m, respectively. Moreover, the emulsification activity and hydrophobicity were determined to be 36.7, 44.9, 35.9, and 53.4%, respectively. The recovery assays included zinc sulfate, ammonium sulfate, acid precipitation, and solvent extraction techniques. All these approaches showed that the amount of biosurfactants correlates to the tested hydrocarbons. Furthermore, the enzyme activity of these two isolates generated significantly more laccase (Lac) than manganese peroxidase (MnP) and lignin peroxidase (LiP), as compared to the control. In conclusion, our study highlights new perspectives on the fungal resources found in persistently polluted terrestrial ecosystems. This knowledge will be useful for bioremediation, safe disposal of petroleum-oil contamination, and other industrial uses.

Abdelghaffar, M., Y. Gamal, R. A. El-Khoribi, W. Soliman, Y. Badr, M. F. O. Hameed, and S. S. A. Obayya, Highly sensitive V-shaped SPR PCF biosensor for cancer detection, , vol. 55, issue 5: Springer, pp. 472, 2023. Abstract
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Abduljalil, J. M., A. M. Elghareib, A. Samir, A. A. Ezat, and A. A. Elfiky, "How helpful were molecular dynamics simulations in shaping our understanding of SARS-CoV-2 spike protein dynamics?", International Journal of Biological Macromolecules, vol. 242, 2023. AbstractWebsite

The SARS-CoV-2 spike protein (S) represents an important viral component that is required for successful viral infection in humans owing to its essential role in recognition of and entry to host cells. The spike is also an appealing target for drug designers who develop vaccines and antivirals. This article is important as it summarizes how molecular simulations successfully shaped our understanding of spike conformational behavior and its role in viral infection. MD simulations found that the higher affinity of SARS-CoV-2-S to ACE2 is linked to its unique residues that add extra electrostatic and van der Waal interactions in comparison to the SARS-CoV S. This illustrates the spread potential of the pandemic SARS-CoV-2 relative to the epidemic SARS-CoV. Different mutations at the S-ACE2 interface, which is believed to increase the transmission of the new variants, affected the behavior and binding interactions in different simulations. The contributions of glycans to the opening of S were revealed via simulations. The immune evasion of S was linked to the spatial distribution of glycans. This help the virus to escape the immune system recognition. This article is important as it summarizes how molecular simulations successfully shaped our understanding of spike conformational behavior and its role in viral infection. This will pave the way to us preparing for the next pandemic as the computational tools are tailored to help fight new challenges. © 2023 Elsevier B.V.

Zhang, M., J. - M. Poumirol, N. Chery, H. Rinnert, A. E. Giba, R. Demoulin, E. Talbot, F. Cristiano, T. Hungria, V. Paillard, et al., "Hyperdoped Si nanocrystals embedded in silica for infrared plasmonics", Nanoscale, vol. 15, issue 16: The Royal Society of Chemistry, pp. 7438 - 7449, 2023. AbstractWebsite

We present the experimental realization of plasmonic hyperdoped Si nanocrystals embedded in silica via a combination of sequential low energy ion implantation and rapid thermal annealing. We show that phosphorus dopants are incorporated into the nanocrystal cores at concentrations up to six times higher than P solid solubility in bulk Si by combining 3D mapping with atom probe tomography and analytical transmission electron microscopy. We shed light on the origin of nanocrystal growth at high P doses, which we attribute to Si recoiling atoms generated in the matrix by P implantation, which likely increase Si diffusivity and feed the Si nanocrystals. We show that dopant activation enables partial nanocrystal surface passivation that can be completed by forming gas annealing. Such surface passivation is a critical step in the formation of plasmon resonance, especially for small nanocrystals. We find that the activation rate in these small doped Si nanocrystals is the same as in bulk Si under the same doping conditions.

Alrowais, F., R. Marzouk, F. N. Al-Wesabi, and A. M. Hilal, "Hand Gesture Recognition for Disabled People Using Bayesian Optimization with Transfer Learning", Intelligent Automation & Soft Computing, vol. 36, issue 3, pp. 3325-3342, 2023.
Omar, H. M., M. M. Fahmy, and M. M. Abuowarda, "Hand palm sparganosis: morphologically and genetically confirmed Spirometra erinaceieuropaei in a fourteen-year-old girl, Egypt", Journal of Parasitic diseases, vol. 47, issue 4, pp. 859–864, 2023.
Laboud, Y. N., H. M. Hassaneen, H. M. E. Hassaneen, M. A. Mohamed Teleb, and F. M. Saleh, "Hantzsch‐like reaction of isoquinoline‐1‐acetonitrile in synthesis of 4 H‐pyrido [2, 1‐a] isoquinolines with antibacterial evaluation", Journal of Heterocyclic Chemistry, vol. 60, issue 9: John Wiley & Sons, Inc. Chichester, UK, pp. 1565-1571, 2023. Abstract
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AbdAlRahman, A., L. A. Said, A. Soltan, and A. G. Radwan, "Hardware Accelerator of Fractional-Order Operator Based on Phase Optimized Filters With Applications", IEEE Transactions on Circuits and Systems I: Regular Papers: IEEE, 2023. Abstract
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Soliman, H. M., A. Saleem, E. Bayoumi, and M. D. Santis, "Harmonic Distortion Reduction of Transformer-Less Grid-Connected Converters by Ellipsoidal-Based Robust Control", energies, vol. 16, issue 3, pp. art. no. 1362, 2023.
Attia, M. M., M. M. Ibrahim, and M. A. Mahmoud, "Heavy infection of the orange-spotted grouper (Epinephelus coioides) with Huffmanela japonica: morphological, ultrastructural identification, tissue reactions and …", Aquaculture International, vol. 31, issue 6, pp. 3311-3327, 2023.
Maghraby, A. E., H. M. R. Hathout, and K. M. AbdelMaksoud, "Heavy metal contamination in the vicinity of gold mine and its environmental impact at Eastern Desert, Egypt", Arabian Journal of Geosciences, vol. 16:, issue 599, 2023.
Gad, S. A., A. S. El-Demerdash, Marwa M. Khalifa, and M. M. Magdy, "Hematological and Molecular Profiling of Some Blood Pathogens in Dog Breeding Farm in Egypt", Journal of Advanced Veterinary Research, vol. 13, issue 3, pp. 344-351, 2023.
Eldin, A. B., M. Ezzat, M. Afifi, O. Sabry, and G. Caprioli, "Herbal medicine: the magic way crouching microbial resistance", Natural Product Research, vol. 37, issue 24, pp. 4280 - 4289, 2023.
Hegazy, W., H. I. Sakr, M. Abdul Hamid, M. A. Abdelaziz, M. Salah, E. S. Abdel Rehiem, and A. Abdel Moneim, "Hesperidin Attenuates Hypothyroidism-Induced Lung Damage in Adult Albino Rats by Modulating Oxidative Stress, Nuclear Factor Kappa-B Pathway, Proliferating Cell Nuclear Antigen and Inflammatory Cytokines.", Biomedicines, vol. 11, issue 6, 2023. Abstract

The occurrence of worsening pulmonary function has been connected to hypothyroidism (HPO). Hesperidin (HES) was suggested to have antioxidant, anti-proliferative, and anti-inflammatory potential. Our study's objective was to determine whether HES could reduce carbimazole (CBZ)-induced lung injury more effectively than Eltroxin (ELT) in adult male albino rats or not. At random, 32 rats were distributed into four groups: Group I: normal control, to induce HPO, the remaining three groups were given CBZ (20 mg/kg/day) dissolved in distilled water for 1 week. They were then split up into three groups. Group II: orally administered CBZ (20 mg/kg b.w in water/day), Group III: HES (200 mg/kg/day) dissolved in 1% carboxymethyl-cellulose + CBZ treated, and Group IV: ELT (0.045 mg/kg/day) dissolved in distilled water + CBZ treated. All treatments were delivered for 12 weeks. Blood was collected to assess thyroid-stimulating hormone (TSH) and thyroid hormones (THs). Lung injury was evaluated based on the pulmonary content of interleukin (IL)-35, IL-6, and tumor necrosis factor-alpha (TNF-α), along with the estimation of lipid peroxidation, catalase, glutathione levels, superoxide dismutase, heme oxygenase-1 (HO-1), and nuclear factor erythroid 2-related factor 2 (Nrf2). The histological, ultrastructural, and immunohistochemical study of nuclear factor Kappa-B (NF-κB) and inducible nitric oxide synthase (iNOS), together with estimating the proliferation of cells using Antigen Ki-67 in lung tissue were performed. HES and ELT primarily suppressed variable lung damage mechanisms by suppressing TSH, the NF-κB/TNF-α pathway, iNOS, lipid peroxidation, Ki-67, and inflammatory mediators. On the other hand, they improved THs, antioxidant parameters, and the Nrf2/HO-1 pathway. HES and ELT exhibited an ameliorative effect that was reflected in the histopathological, immunohistochemical, and ultrastructural results. These results indicate that HES is a pneumoprotective agent that could be a promising treatment for oxidative stress, inflammation, and proliferation.

Amer, W. M., N. A. M. Shaye, M. O. Hassan, and M. M. Khalaf, "Heteroblastic Inflorescence of Lamium amplexicaule L. in Egyptian Flora", Plants, vol. 12, issue 1028, pp. 1-25, 2023. 2023-plants-lamium.pdf
Abazeed, A., "Heterogeneity of Water Justice and the Question of Nile Solidarity", Agrarian South: Journal of Political Economy, vol. 12, issue 2, pp. 187-205, 2023.