Publications

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Thesis
Ibrahim, M. K., H. A. El-Akabawy, M. M. Kenawy, and H. H. Mahmoud, Hyperchloremia as a risk factor for acute kidney injury in septic shock patients, , Cairo, Cairo University, 2018.
Patent
Mohieldin, A. N., A. Bellaouar, S. Embabi, and M. Frichette, High Frequency Tunable Filter, : Texas Instruments, 2003.
Newspaper Article
M, H., E. y A, M. A, M. M, A. N, G. A, M. Z, A. B, S. M, and E. G, "Hepatitis C virus treatment by direct-acting antivirals in successfully treated hepatocellular carcinoma and possible mutual impact", European Journal of Gastroenterology & Hepatology 30(8):1, pp. 876-881, 2018.
Elsaman, R., "A Historic Opportunity to Rebuild Egypt’s Economy", Mada Masr, 2013.
Miscellaneous Section
Eman, H. I., K. M. S. Reda, T. A. S. E. Din, and A. M. Bakeer, "Histopathological and clinicopathological studies on the antioxidant effect of gold nanoparticles in diethylnitrosamine induced hepatocarcinogenesis in rats", veterinary medical journal, Giza, vol. 62(1), issue 1110-1423, pp. 1-7, 2016. puplications.pdf
Miscellaneous
Mohammed, R. H. A., A. Goyal, and P. Bansal, Hand and Wrist Rheumatoid Arthritis, , 2020.
El-Beshlawy, A., A. A. Salam, G. Fathy, K. M. Salamaa, M. E. Ghamrawy, S. S. Ramadan, and A. M. Elhaddad, Hematopoietic Stem Cell Transplantation in Βthalassemia Major: The Egyptian Outcome, : American Society of Hematology Washington, DC, 2019. Abstract
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Hassan, N., N. Bückreiß, J. Efing, M. Schulz-Fincke, P. König, B. Greve, G. Bendas, and M. Götte, "The Heparan Sulfate Proteoglycan Syndecan-1 Triggers Breast Cancer Cell-Induced Coagulability by Induced Expression of Tissue Factor", Cells, vol. 12, issue 6, 2023. Abstract

Syndecan-1 (Sdc-1) upregulation is associated with poor prognosis in breast cancer. Sdc-1 knockdown results in reduced angiogenesis and the dysregulation of tissue factor (TF) pathway constituents. Here, we evaluate the regulatory mechanisms and functional consequences of the Sdc-1/TF-axis using Sdc-1 knockdown and overexpression approaches in MCF-7 and MDA-MB-231 breast cancer cells. Gene expression was analyzed by means of qPCR. Thrombin generation and cell migration were detected. Cell-cycle progression and apoptosis were investigated using flow cytometry. In MDA-MB-231 cells, IL6, IL8, VEGF, and IGFR-dependent signaling affected TF pathway expression depending on Sdc-1. Notably, Sdc-1 depletion and TF pathway inhibitor (TFPI) synergistically affected PTEN, MAPK, and STAT3 signaling. At the functional level, the antiproliferative and pro-apoptotic effects of TFPI depended on Sdc-1, whereas Sdc-1’s modulation of cell motility was not affected by TFPI. Sdc-1 overexpression in MCF-7 and MDA-MB-231 cells led to increased TF expression, inducing a procoagulative phenotype, as indicated by the activation of human platelets and increased thrombin formation. A novel understanding of the functional interplay between Sdc-1 and the TF pathway may be compatible with the classical co-receptor role of Sdc-1 in cytokine signaling. This opens up the possibility of a new functional understanding, with Sdc-1 fostering coagulation and platelet communication as the key to the hematogenous metastatic spread of breast cancer cells.

Soliman, S. S., Hierarchically Clustered Wireless Sensor Networks: Lifetime Optimization Techniques, : LAP LAMBERT Academic Publishing, 2012. Abstract
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ElZomor, H., H. Taha, A. Aleieldin, R. Nour, M. S. Zaghloul, M. Fawzi, A. Kamel, and A. S. AlFaar, "High Risk Retinoblastoma; prevalence and success of treatment in developing countries", Ophthalmic Genetics, 2015. Abstract
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Emira, A. A., M. AbdelGhany, M. Y. Elsayed, A. M. Elshurafa, and K. N. Salama, High voltage charge pump, : US Patent 9,306,450, 2016. Abstract
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El-Beltagy, M., A. Naiem, and F. Essayadi, Highest Bandwidth Download Request Policy in a Live Streaming P2P Network, : Google Patents, dec # " 19", 2012. Abstract
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Sharaf El-Din, H. A., HONEYBEE QUEENS PERFORMANCE IN RELATION TO THEIR LONG PERIOD STORAGE IN‎ QUEEN-RIGHT COLONIES, : Faculty of Agriculture, Cairo university, 2016. Abstract
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Elfiky, A. A., and I. M. Ibrahim, "Host-cell recognition through GRP78 is enhanced in the new UK variant of SARS-CoV-2, in silico", Journal of Infection, vol. 82, issue 5, pp. 186 - 230, 2021. Abstract
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Potts, C., Human and {Organisational} {Factors} and {Environments} for {Information} {System} {Design}, , no. DoC 86/6: Department of Computing, Imperial College of Science, Technology & Medicine, University of London, 1986. Abstract

users need to evaluate IS while still under development

Elfiky, A. A., "Human papillomavirus E6: Host cell receptor, GRP78, binding site prediction", Journal of Medical Virology, vol. 92, issue 12, pp. 3759 - 3765, 2020. Abstract
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Elmoselhy, S. A., B. S. Azzam, S. M. Metwalli, and H. H. Dadoura, Hybrid Shape Optimization and Failure Analysis of Laminated Fibrous Composite E-Springs for Vehicle Suspension, : SAE Technical Paper, 2006. Abstract
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Gates, T., M. Helal, and W. D. Ree, Hydraulic Design of a Canal System for Gravity Irrigation, : EWUP, 1984. Abstract
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