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2021
Sultan, A. M., A. E. W. E. Ghareeb, A. Farag, and H. A. Abdelrahman, "Histopathological study on the effect of allopurinol on the rat pups", Ciência e Técnica Vitivinícola, vol. 36, issue 10, pp. 46-59, 2021.
Zaki, A. R., A. A. A. Khalaf, Marwa A Ibrahim, A. M. Mekkawy, and P. A. Noshy, "Histopathological, immunohistochemical and molecular changes in the lung, heart and skin of drowned rats at different postmortem intervals", Histopathological, immunohistochemical and molecular changes in the lung, heart and skin of drowned rats at different postmortem intervals, vol. 24, issue 3 and 4, pp. 34-48, 2021.
Zaki, A. R., A. A. A. Khalaf, M. A. Ibrahim, A. M. Mekkawy, and P. A. Noshy, "Histopathological, immunohistochemical and molecular changes in the lung, heart and skin of drowned rats at different postmortem intervals.", International Journal of Medical Toxicology & Legal Medicine, vol. 24, pp. 34-48, 2021.
Abdelhafiz, A. S., A. Ali, M. A.Fouda, D. M.Sayed, M. M. Kamel, L. M. Kamal, M. A. Khalil, and R. M.Bakry, "HLA-B*15 predicts survival in Egyptian patients with COVID-19", Human Immunology, 2021. AbstractWebsite

Genetic differences among individuals could affect the clinical presentations and outcomes of COVID-19. Human Leukocyte Antigens are associated with COVID-19 susceptibility, severity, and prognosis. This study aimed to identify HLA-B and -C genotypes among 69 Egyptian patients with COVID-19 and correlate them with disease outcomes and other clinical and laboratory data. HLA-B and -C typing was performed using Luminex-based HLA typing kits. Forty patients (58%) had severe COVID-19; 55% of these patients died, without reported mortality in the moderate group. The alleles associated with severe COVID-19 were HLA-B*41, -B*42, -C*16, and -C*17, whereas HLA-B*15, -C*7, and -C*12 were significantly associated with protection against mortality. Regression analysis showed that HLA-B*15 was the only allele associated with predicted protection against mortality, where the likelihood of survival increased with HLA-B*15 (P < 0.001). Patient survival was less likely to occur with higher total leukocytic count, ferritin, and creatinine levels. This study provides interesting insights into the association between HLA class I alleles and protection from or severity of COVID-19 through immune response modulation. This is the first study to investigate this relationship in Egyptian patients. More studies are needed to understand how HLA class I alleles interact and affect Cytotoxic T lymphocytes and natural killer cell function.

Habib, E. I., M. S. Elsheemy, ahmed hossam, S. morsy, H. A. Hussein, A. Y. Abdelaziz, M. S. Abdelazim, and H. Fathy, "Holmium Laser Enucleation Versus Bipolar Plasmakinetic Resection for Management of Lower Urinary Tract Symptoms in Patients with Large-Volume Benign Prostatic Hyperplasia: Randomized-Controlled Trial.", Journal of endourology, vol. 35, issue 2, pp. 171-179, 2021. Abstract

To compare the safety and efficacy of holmium laser enucleation of prostate (HoLEP) bipolar plasmakinetic resection of prostate (BPRP) in the management of large-sized (≥75 g) benign prostatic hyperplasia (BPH). This randomized-controlled trial recruited 145 symptomatic BPH patients who had failed medical management, and who had undergone either HoLEP (Versa pulse 100 W;  = 73) or BPRP (AUTOCON II 400 ESU;  = 72). Both groups were compared using the Mann-Whitney, chi-square, Student-, or Fisher exact tests as appropriate. Preoperative postoperative findings (24 months) were compared using paired -test or Wilcoxon signed-rank test. The two groups were comparable for most preoperative findings including prostate size ( = 0.629), although HoLEP included more patients on anticoagulants ( = 0.001). HoLEP was associated with significantly less operative duration ( < 0.001), hemoglobin loss ( < 0.001), catheterization duration ( = 0.009), and hospital stay ( < 0.001). There was no significant difference in total complications ( = 0.291) and each separate complication. Blood transfusion was reported only with BPRP ( = 0.058). At 24 months of follow-up, there was significant improvement in all the parameters in each group (International Prostate Symptom Score [IPSS], maximum urinary flow rate [Q] quality of life [QoL], and postvoid residual urine [PVRU];  < 0.001). There was no significant difference between both groups in postoperative IPSS ( = 0.08), Q ( = 0.051), QoL ( = 0.057), or PVRU ( = 0.069). There was significantly better percentage improvement of both IPSS ( = 0.006) and QoL ( = 0.025) in HoLEP. HoLEP and smaller removed (resected or enucleated) tissues were associated with a reduction in the primary outcomes (hemoglobin loss and operative duration) in logistic regression analysis. HoLEP showed better safety profile with significantly less operative duration, hemoglobin loss, hospital stay, and catheterization duration. Although both procedures were effective, HoLEP showed significantly better percentage improvement of both IPSS and QoL. ClinicalTrials.gov Identifier: NCT04143399.

Latifi, F., Z. Baruti-Gafurri3, I. Haziri, S. Manxhuka-Kërliu, L. Shahini, A. Podrimaj-Bytyqi, A. Sinani, and S. S. Abdelgayed, "Hormonal and Histopathological Fertility Assessments of Male Dogs in Kosovo", Indian Journal of Animal Research, vol. 55, issue 4, pp. 433-438, 2021. final-attachment-published-b-1267.pdf
Muhammed, E. S. E., S. A. ElRahman, A. AlAhwany, and A. E. W. E. Ghareeb, "HORMONAL CHANGES IN MEN SUFFERING FROM NON OBSTRUCTIVE AZOOSPERMIA AND SECONDARY INFERTILITY", Ciência e Técnica Vitivinícola, vol. 36, issue 6, pp. 81-93, 2021.
Atta, N. F., A. Galal, Y. M. Ahmed, and M. G. Abdelkader, "Host guest inclusion complex/polymer-CNT composite for efficient determination of uric acid in presence of interfering species", Journal of Electroanalytical Chemistry, vol. 882, pp. 115012, 2021.
Elfiky, A., and I. M. Ibrahim, "Host-cell recognition through GRP78 is enhanced in the new UK variant of SARS-CoV-2, in silico", Journal of Infection, 2021.
Elfiky, A. A., and I. M. Ibrahim, "Host-cell recognition through GRP78 is enhanced in the new UK variant of SARS-CoV-2, in silico", Journal of Infection, vol. 82, no. 5: Elsevier, pp. 186–230, 2021. Abstract
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asmaa ahmed sayed, M. M. Ahmed, I. Talat, S. S. A. Soliman, and S. Fares, "House officers choice of Family medicine speciality amid the implementation of the New Universal Health Insurance Low", Jounal of primary care and community Health, issue 2150-1319, 2021.
Mansour, S., S. Wallace, V. Sadiraj, and M. Hassan, "How Do Electoral and Voice Accountability Affect Corruption? Experimental Evidence from Egypt", European Journal of Political Economy, vol. 68, issue June 2021, pp. 101994, 2021.
Mansour, S., S. Wallace, V. Sadiraj, and M. Hassan, "How Do Electoral and Voice Accountability Affect Corruption? Experimental Evidence from Egypt", European Journal of Political Economy, vol. 68, issue June 2021, pp. 101994, 2021.
El-Komy, M. H. M., A. Abdelnaby, and M. El-Kalioby, "How does COVID-19 impact psoriasis practice, prescription patterns, and healthcare delivery for psoriasis patients? A cross-sectional survey study.", Journal of cosmetic dermatology, 2021. Abstract

BACKGROUND: Psoriasis is a chronic skin disease that needs continuous medical care. During COVID-19, delivering medical service was negatively affected.

AIMS: To describe the impact of COVID-19 on psoriasis healthcare delivery, management, and practice.

METHODS: This observational cross-sectional study was conducted on 197 dermatologists using a validated online questionnaire. The survey evaluated the effect of COVID-19 on the decisions, prescription patterns, appointments rescheduling, and healthcare delivery for psoriasis patients by dermatologists. The questionnaire was developed and validated with a reliability score >0.7.

RESULTS: During the pandemic, most dermatologists delayed initiating biological/immunosuppressive therapy for psoriasis unless urgently needed by the patient. For patients already receiving biologics or immunosuppressive treatment, most dermatologists favored continuation of therapy. Almost half (44.2%) of participants do not perform SARS-CoV-2 PCR screening before initiating biologics/immunosuppressive therapy. Dermatologists also reported an increased prescription of topical medications (79.2%), natural sunlight (28.4%), acitretin (26.9%), and home UVB (21.3%). Opinions regarding the use of hydroxychloroquine for COVID-19 treatment/prophylaxis for psoriasis patients were controversial. Intervals between face-to-face follow-up visits were prolonged by 71.6% of dermatologists. More than half of participants reported that their patients discontinued treatment without medical consultation. More than three fourth of responders either agreed or strongly agreed that COVID-19 negatively affected psoriasis patients.

CONCLUSIONS: The COVID-19 pandemic has a negative impact on psoriasis management and healthcare delivery. Dermatologists are cautious about using biologics and immunosuppressive drugs during the pandemic, making case-by-case decisions. Psoriasis patients need compliance monitoring, and psychological support during the pandemic, which can be facilitated by teledermatology.

Mahmoudi, M., W. Bejaoui, M. B. Ali, A. Hedfi, M. Almalki, N. Essid, E. Mahmoudi, R. Rizk, O. Pacioglu, D. Urkmez, et al., "How effective is wastewater treatment? A case study under the light of taxonomic and feeding features of meiobenthic nematodes", Environmental Science and Pollution Research, vol. 29, issue 2022, pp. 2566–2578, 2021.
Bofana, J., M. Zhang, B. Wu, H. Zeng, M. Nabil, N. Zhang, A. Elnashar, F. Tian, J. M. da Silva, A. Botão, et al., "How long did crops survive from floods caused by Cyclone Idai in Mozambique detected with multi-satellite data", Remote Sensing of Environment, vol. 269, pp. 112808, 2021. AbstractWebsite

Floods are causing massive losses of crops and agricultural infrastructures in many regions across the globe. During the 2018/2019 agricultural year, heavy rains from Cyclone Idai caused flooding in Central Mozambique and had the greatest impact on Sofala Province. The main objectives of this study are to map the flooding durations, evaluate how long crops survived the floods, and analyse the dynamics of the affected crops and their recovery following various flooding durations using multi-source satellite data. Our results indicate that Otsu method-based flooding mapping provides reliable flood extents and durations with an overall accuracy higher than 90%, which facilitates the assessment of how long crops can survive floods and their recovery progress. Croplands in both Buzi and Tica administrative units were the most severely impacted among all the regions in Sofala Province, with the largest flooded cropland extent at 23,101.1 ha in Buzi on 20 March 2019 and the most prolonged flooding duration of more than 42 days in Tica and Mafambisse. Major summer crops, including maize and rice, could survive when the fields were inundated for up to 12 days, while all crops died when the flooding duration was longer than 24 days. The recovery of surviving crops to pre-flooding status took a much longer time, from approximately 20 days to as long as one month after flooding. The findings presented herein can assist decision making in developing countries or remote regions for flood monitoring, mitigation and damage assessment.

Aboelhassan, R., S. Ali, M. Ali, and N. A. Abdel-Fatah, "How much can GIT cancer patients afford for effective and safe treatment?", Annals of Oncology, vol. 32, issue S3, pp. S98-S99, 2021.
Abou-Elella, G. M., MOURAD FAHMY HASSAN, E. M. A. K. Elsaeidy, M. S. Nawar, and I. M. Zidan, "How organic medicinal plants affect life table parameters of Tetranychus urticae (Acari: Tetranychidae)?", Persian Journal of Acarology, vol. 10, issue 1, pp. 69-83, 2021. Abstract
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Kar, M., N. Muluk, and H. Negm, "How Should Rhinitis Be Managed During Pregnancy", Challenges in Rhinology: Springer, 2021.
Issak, M., M. M. Ali, S. H. N. Taha, F. A. Mahmoud, H. A. Zaghla, M. K. Nour, S. F. Ibrahim, and A. S. Alsawii, "HPLC DETECTION OF SERUM AND URINARY PARAPHENYLENE DIAMINE (PPD) LEVEL AND ITS METABOLITES IN RELATION TO CARDIAC TOXICITY", Egypt J. Forensic Sci. Appli. Toxicol. , vol. 21, issue 3, pp. 31-42, 2021.
Okba, M., R. El-Shiekh, M. Abu-Elghait, M. Sobeh, and R. Ashour, "HPLC-PDA-ESI-MS/MS Profiling and Anti-Biofilm Potential of Eucalyptussideroxylon Flowers", Antibiotics, vol. 10, issue 761, 2021.
Fayed, A. S., M. A. Hegazy, E. B. Kamel, and M. S. Eissa, "HPLC-UV and TLC-Densitometry Methods for Simultaneous Determination of Sofosbuvir and Daclatasvir: Application to Darvoni® Tablet", Journal of Chromatographic Science, 2021. Abstract
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