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2024
Marey Mahmoud, H. H., A. M. A. Kamel, and M. F. Ali, "Developing Low Cost Eco-friendly Restoration Mortars for Historic Lime-based Stucco and Building Materials", Periodica Polytechnica: Civil Engineering, vol. 68, issue 2, pp. 657 - 668, 2024.
H. Marey Mamoud, A. Kamel, A. M. F., "Developing Low Cost Eco-friendly Restoration Mortars for Historic Lime-based Stucco and Building Materials", Periodica Polytechnica Civil Engineering, vol. 68, issue 2, pp. 657–668, 2024.
Galal, S. A. B., E. S. ElZanfaly, E. M. Hussien, E. A. H. Amer, and H. E. Zaazaa, "Development of chromatographic methods to determine multivitamins formulation depending on their solubility and polarity: comparative study using three greenness assessment tools", BMC chemistry, vol. 18, no. 1: Springer International Publishing Cham, pp. 20, 2024. Abstract
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Anter, A., M. A. N. El-Ghany, M. I. M. Ibrahim, R. A. Charmy, M. Yosri, and H. Tallima, "Development of user-friendly protocols for single-cell arachidonic acid production in developing countries", Bioresource Technology Reports, vol. 25, pp. 101737, 2024.
Mohamed, H. M., and Z.A.R.Khamis, "Diagnosis of the deterioration and conservation of Bes pottery jar from the tomb of Petah Umm Uya in Saqqara", International Journal of Conservation Science, vol. 15, pp. 449-460, 2024. diagnosis_of_the_deterioration_and_conservationr.pdf
Omar, S., M. F. Ali, and A. E. samar Ghania, "Diagnostic Investigation and Conservation Methods of the Wall Ceramic Mosaic in The Historical Church of the Blessed Virgin Mary, Mostorod, Egypt", Shedet, vol. 12 , issue 12, pp. 398 - 419, 2024.
Mandouh, M. I., I. B. Shaheed, M. Bionaz, A. A. Elolimy, H. A. Mansour, S. A. Mohamed, M. M. El-Attrouny, O. A. A. Farid, M. R. Mousa, and A. M. Abdelatty, "Dietary hydrolyzed soya lecithin affects feed intake, abundance of bacteria in the caecum, fatty acid composition and area of adipocytes in pre-mating primiparous V-line female rabbit.", Journal of animal physiology and animal nutrition, vol. 108, issue 3, pp. 557-565, 2024. Abstract

This study aimed at investigating the effect of hydrolyzed soya lecithin; also called lysolecithin or lysophosphatidylcholine, on growth performance, caecal microbiota and fat depots in pre-breeding primiparous rabbits does. For this, 60 V-Line primiparous rabbits does (5-6 months) were used in a 30-day experiment. Does were allotted into three iso-nitrogenous iso-caloric dietary treatments (n = 20/group) as follows: (1) CON received 0% soya lecithin, (2) LECL group was fed a basal diet supplemented with 0.5% soya lecithin and (3) LECH group was fed a basal diet supplemented with 1% soya lecithin. Growth performance indices were measured, caecum samples were collected for measurement of specific bacteria via qPCR, and several fat depots including periovarian fat were sampled for adipocyte morphometry and fatty acid profiling. Statistical analysis was performed using GLM procedures of SAS v9.4. Soya lecithin increased feed intake (p < 0.05). The abundance of caecal Bifidobacteria species, Ruminococcus species and phylum Butryvibrio-specific genes increased (p < 0.05) in rabbits receiving soya lecithin in their diet, soya lecithin increased the level of polyunsaturated fatty acids in subcutaneous and perirenal fat (p < 0.05) and increased the level of monounsaturated fatty acids in periovarian fat (p < 0.05); additionally, the adipocyte area increased in periovarian and perirenal fat (p < 0.05). In conclusion, soya lecithin at a dose of 0.5% increased feed intake and energy storage in adipocytes and improved the fatty acid profile of periovarian fat.

Hossam-Elden, N., N. Abu-Elala, S. E. Ali, M. S. Khattab, and M. S. Marzouk, "Dietary Immune Nutritive Effect of Chitosan/Chitosan Nanoparticles on the Nile Tilapia: Short-term Exposure", Egyptian Journal of Aquatic Biology and Fisheries, vol. 28, pp. 157 - 183, 2024.
Hossam-Elden, N., N. Abu-Elala, S. E. Ali, M. S. Khattab, and M. S. Marzouk, "Dietary Immune Nutritive Effect of Chitosan/Chitosan Nanoparticles on the Nile Tilapia: Short-term Exposure", Egyptian Journal of Aquatic Biology and Fisheries, vol. 28, pp. 157 - 183, 2024.
Al-Suwailem, N. K., N. N. Kamel, A. O. Abbas, F. S. Nassar, D. A. A. Elsayed, G. F. Gouda, and H. M. Safaa, "Dietary Moringa Leaf Supplementation Affects Heat-Stressed Broilers: II-Blood Metabolites, Antioxidant Activity and Meat Quality", Advances in Animal and Veterinary Sciences, vol. 12, issue 6, pp. 1066-1073, 2024.
Mahdally, N. H., R. A. ElShiekh, B. Thissera, A. Eltaher, A. Osama, M. Mokhtar, N. M. Elhosseiny, M. O. N. A. T. KASHEF, S. Magdeldin, and A. M. El Halawany, "Dihydrophenazine: a multifunctional new weapon that kills multidrug-resistant Acinetobacter baumannii and restores carbapenem and oxidative stress susceptibilities", Journal of Applied Microbiology, vol. 135, issue 5: Oxford University Press, pp. lxae100, 2024. Abstract
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Mahdally, N. H., R. A. ElShiekh, B. Thissera, A. Eltaher, A. Osama, M. Mokhtar, N. M. Elhosseiny, M. O. N. A. T. KASHEF, S. Magdeldin, A. M. El Halawany, et al., "Dihydrophenazine: a multifunctional new weapon that kills multidrug-resistant Acinetobacter baumannii and restores carbapenem and oxidative stress susceptibilities", Journal of Applied Microbiology, vol. 135, no. 5: Oxford University Press, pp. lxae100, 2024. Abstract
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Mahdally, N. H., R. A. ElShiekh, B. Thissera, A. Eltaher, A. Osama, M. Mokhtar, N. M. Elhosseiny, M. O. N. A. T. KASHEF, S. Magdeldin, A. M. El Halawany, et al., "Dihydrophenazine: A multifunctional new weapon that kills multidrug-resistant Acinetobacter baumannii and restores carbapenem and oxidative stress susceptibilities.", Journal of applied microbiology, 2024. Abstract

AIMS: The current work aims to fully characterize a new antimicrobial agent against Acinetobacter baumannii, which continues to represent a growing threat to healthcare settings worldwide. With minimal treatment options due to the extensive spread of resistance to almost all the available antimicrobials, the hunt for new antimicrobial agents is a high priority.

METHODS AND RESULTS: An Egyptian soil-derived bacterium strain NHM-077B proved to be a promising source for a new antimicrobial agent. Bio-guided fractionation of the culture supernatants of NHM-077B followed by chemical structure elucidation identified the active antimicrobial agent as 1-hydroxy phenazine. Chemical synthesis yielded more derivatives, including dihydrophenazine (DHP), which proved to be the most potent against A. baumannii, yet it exhibited a safe cytotoxicity profile against human skin fibroblasts. Proteomics analysis of the cells treated with DHP revealed multiple proteins with altered expression that could be correlated to the observed phenotypes and potential mechanism of the antimicrobial action of DHP. DHP is a multi-pronged agent that affects membrane integrity, increases susceptibility to oxidative stress, interferes with amino acids/protein synthesis, and modulates virulence-related proteins. Interestingly, DHP in sub-inhibitory concentrations re-sensitizes the highly virulent carbapenem-resistant A. baumannii strain AB5075 to carbapenems providing great hope in regaining some of the benefits of this important class of antibiotics.

CONCLUSIONS: This work underscores the potential of DHP as a promising new agent with multifunctional roles as both a classical and non-conventional antimicrobial agent that is urgently needed.

Ali, I., K. Wassif, and H. Bayomi, "Dimensionality reduction for Images of IoT using Machine Learning", Scientific Reports, vol. Volume 14, 2024.
Moustafa, E. A., H. A. Allam, M. A. Fouad, E. A. M. Kerdawy, N. N. E. El-Sayed, C. Wagner, H. A. Abdel-Aziz, and M. A. Ezzat, "Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer’s disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation", Bioorganic Chemistry , vol. 146, pp. 107324, 2024. paper24.pdf
Moustafa, E. A., H. A. Allam, M. A. Fouad, E. A. M. Kerdawy, N. N. E. El-Sayed, C. Wagner, H. A. Abdel-Aziz, and M. A. Ezzat, "Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer’s disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation", Bioorganic Chemistry , vol. 146, pp. 107324, 2024. paper24.pdf
Moustafa, E. A., H. A. Allam, M. A. Fouad, E. A. M. Kerdawy, N. N. E. El-Sayed, C. Wagner, H. A. Abdel-Aziz, and M. A. Ezzat, "Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer’s disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation", Bioorganic Chemistry , vol. 146, pp. 107324, 2024. paper24.pdf
Moustafa, E. A., H. A. Allam, M. A. Fouad, E. A. M. Kerdawy, N. N. E. El-Sayed, C. Wagner, H. A. Abdel-Aziz, and M. A. Ezzat, "Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer’s disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation", Bioorganic Chemistry , vol. 146, pp. 107324, 2024. paper24.pdf
Moustafa, E. A., H. A. Allam, M. A. Fouad, E. A. M. Kerdawy, N. N. E. El-Sayed, C. Wagner, H. A. Abdel-Aziz, and M. A. Ezzat, "Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer’s disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation", Bioorganic Chemistry , vol. 146, pp. 107324, 2024. paper24.pdf
EL-Hady, M., M. H. Abbas, F. A. Khanday, L. A. Said, and A. G. Radwan, "DISH: Digital image steganography using stochastic-computing with high-capacity", Multimedia Tools and Applications: Springer US New York, pp. 1-16, 2024. Abstract
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Mohamed, E. L., M. H. Abbas, F. A. Khanday, L. A. Said, and A. G. Radwan, DISH: Digital image steganography using stochastic-computing with high-capacity, , 2024. Abstract
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Saleh, S. M., O. S. El-Tawil, M. B. Mahmoud, S. S. Abd El-Rahman, E. M. El-Saied, and P. A. Noshy, "Do Nanoparticles of Calcium Disodium EDTA Minimize the Toxic Effects of Cadmium in Female Rats?", Biological trace element research, vol. 202, issue 5, pp. 2228-2240, 2024. Abstract

The present study aims to investigate the ability of CaNa2EDTA (ethylenediaminetetraacetic acid) macroparticles and nanoparticles to treat cadmium-induced toxicity in female rats and to compare their efficacies. Forty rats were divided into 4 equal groups: control, cadmium, cadmium + CaNaEDTA macroparticles and Cd + CaNaEDTA nanoparticles. Cadmium was added to the drinking water in a concentration of 30 ppm for 10 weeks. CaNaEDTA macroparticles and nanoparticles (50 mg/kg) were intraperitoneally injected during the last 4 weeks of the exposure period. Every two weeks, blood and urine samples were collected for determination of urea, creatinine, metallothionein and cadmium concentrations. At the end of the experiment, the skeleton of rats was examined by X-ray and tissue samples from the kidney and femur bone were collected and subjected to histopathological examination. Exposure to cadmium increased the concentrations of urea and creatinine in the serum and the concentrations of metallothionein and cadmium in serum and urine of rats. A decrease in bone mineralization by X-ray examination in addition to various histopathological alterations in the kidney and femur bone of Cd-intoxicated rats were also observed. Treatment with both CaNaEDTA macroparticles and nanoparticles ameliorated the toxic effects induced by cadmium on the kidney and bone. However, CaNaEDTA nanoparticles showed a superior efficacy compared to the macroparticles and therefore can be used as an effective chelating antidote for treatment of cadmium toxicity.