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Zaghloul, M. A. S., M. Wang, G. Milione, M. - J. Li, S. Li, Y. - K. Huang, T. Wang, and K. P. Chen, "Discrimination of temperature and strain in Brillouin optical time domain analysis using a multicore optical fiber", Sensors, vol. 18, issue 4: Multidisciplinary Digital Publishing Institute, pp. 1176, 2018. Abstract
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saied zaghloul, H., "Does Aroclor 1254 Affect the Reproductive and Thyroid Function Male Albino Rats? ", the 5th Annual Scientific Conference of Forensic Medicine and Toxicology Department, Faculty of Medicine, Cairo University, November, 2001, November,2001.
ZAHER, H., D. Bassiouny, R. A. N. I. A. ABDEL HAY, N. E. S. R. I. N. SAMIR, N. Ragab, and S. Sayed, "Dermoscopic and Immunohistochemical Changes in Acquired Melanocytic Nevi following Narrow-Band Ultraviolet B Therapy.", Dermatology (Basel, Switzerland), vol. 232, issue 3, pp. 273-8, 2016. Abstract

BACKGROUND: Acquired melanocytic nevi (AMN) have been reported to undergo morphological and dermoscopic changes following exposure to narrow-band ultraviolet B (NB-UVB) radiation.

OBJECTIVE: To study the morphological, dermoscopic and immunohistochemical changes in AMN following NB-UVB radiation.

METHODS: Suberythemogenic NB-UVB sessions were delivered to 40 patients with AMN. For each patient, a minimum of 2 nevi were selected. One nevus was surgically removed from each patient prior to sessions as control; for the other nevus, dermoscopic images were captured before and after NB-UVB sessions. The images were evaluated for changes. At the end, another nevus was surgically removed for immunohistochemical assessment of Ki-67 and melan-A.

RESULTS: Our study showed a statistically significant increase in the size of AMN following NB-UVB radiation. Benign dermoscopic changes were observed. Statistically significant positive correlations were found between some dermoscopic findings and the total cumulative dose of NB-UVB. Immunohistochemical analysis did not show any significant change in the exposed AMN.

CONCLUSION: AMN irradiated with repeated suberythemogenic doses of NB-UVB showed benign morphological and dermoscopic changes, and this was confirmed by our immunohistochemical study.

ZAHER, H., D. Bassiouny, R. Abdel Hay, N. E. S. R. I. N. SAMIR, N. Ragab, and S. Sayed, "Dermoscopic and Immunohistochemical Changes in Acquired Melanocytic Nevi following Narrow-Band Ultraviolet B Therapy", Dermatology, vol. 232, no. 3: Karger Publishers, pp. 273–278, 2016. Abstract
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ZAHER, H., D. Bassiouny, R. Abdel Hay, N. E. S. R. I. N. SAMIR, N. Ragab, and S. Sayed, "Dermoscopic and Immunohistochemical Changes in Acquired Melanocytic Nevi following Narrow-Band Ultraviolet B Therapy", Dermatology, vol. 232, issue 3: Karger Publishers, pp. 273-8, 2016. Abstract

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ZAHER, A. S. H. R. A. F. F., A. El-Malah, and Z. Mahmoud, "Design, Synthesis and Anticancer Screening of Novel Benzothienopyarno Fused System: A Step in Discovering a Promising Anticancer Motif", Der Pharma Chemica, 2017,), vol. 9, issue 13, pp. 68-79, 2017. aza_paper.pdf
ZAHER, A. S. H. R. A. F. F., A. El-Malah, and Z. Mahmoud, "Design, Synthesis And Anticancer Screening Of Novel Benzothienopyarno Fused System: A Step In Discovering A Promising Anticancer Agent", Der Pharma Chemica, vol. 9, issue 13, pp. 68-79, 2017.
Zaid, S. A., O. A. Mahgoub, K. Elmetwally, and S. E. Abo-Shady, "Direct Torque Control of a Six Phase Induction Motor Drive", Journal of Engineering and Applied Science, issue 56, 2009. Abstract
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Zaid, H. A. A., S. A. Akl, M. A. E. Ela, A. El-Banbi, and M. H. Sayyouh, "Development of an analytical model to predict oil reservoirs performance using mechanical waves propagation", Journal of Engg. Research - Online First Artical, vol. DOI:10.36909/jer.14863, pp. 15, 2021. hesham_abu_zaid-2021.pdf
Zaid, S. A., O. A. Mahgoub, K. El-Metwally, and S. E. Abo-Shady, "Dual Inverter Based Direct Torque Control of a Six Phase Induction Motor", Journal of Engineering and Computer Science (QJECS), vol. 3, issue 1, 2010. Abstract
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Zakaria, M., and O. Khashaba, "Diagnostic accuracy of the mean platelet volume in oral lichen planus", Journal of The Arab Society for Medical Research, vol. 14, issue 1687-4293, pp. 52–56, 2019.
Zaki, H., M. Nassef, A. A. Badr, and A. F. Al-Sadek, "Discovering the Relationship between Heat-Stress Gene Expression and Gene SNPs Features using Rough Set Theory", International Journal of Advanced Computer Science and Applications(IJACSA), issue 2, pp. 90-98, 2020.
Zaki, I., M. K. Abdelhameid, I. M. El-Deen, K. O. Mohamed, A. H. A. A. Wahab, and A. M. Ashmawy, "Design, synthesis and screening of 1, 2, 4-triazinone derivatives as potential antitumor agents with apoptosis inducing activity on MCF-7 breast cancer cell line", European Journal of Medicinal Chemistry, vol. 156, issue -, pp. 563-579, 2018.
Zaki, S. A., H. Zhu, J. Yao, A. R. Sayed, and M. A. Abdelbaky, "Detection and localization the open and short circuit faults in PV system: A MILP approach", 2020 Asia Energy and Electrical Engineering Symposium (AEEES): IEEE, pp. 187-193, 2020. Abstract
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Zaki, B. M., E. A. Mahmoud, and A. A. Aly, "Diacerein: A potential therapeutic drug for the management of experimental periodontitis in rats.", Electronic physician, vol. 7, no. 5: The Electronic Physician, pp. 1290–1295, 2015. Abstract
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Zaki, S. M., S. A. Fattah, and D. S. Hassan, "The differential effects of high-fat and high- -fructose diets on the liver of male albino rat and the proposed underlying mechanisms.", Folia morphologica, vol. 78, issue 1, pp. 124-136, 2019. Abstract

BACKGROUND: The Western-style diet is characterised by the high intake of energy- -dense foods. Consumption of either high-fructose diet or saturated fat resulted in the development of metabolic syndrome. Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome. Many researchers studied the effect of high-fat diet (HFD), high-fructose diet (HFruD) and high-fructose high-fat diet (HFHF) on the liver. The missing data are the comparison effect of these groups i.e. are effects of the HFHF diet on the liver more pronounced? So, this study was designed to compare the metabolic and histopathological effect of the HFD, HFruD, and HFHF on the liver. The proposed underlying mechanisms involved in these changes were also studied.

MATERIALS AND METHODS: Twenty four rats were divided into four groups: con- trol, HFD, HFruD, and HFHF. Food was offered for 6 weeks. Biochemical, light microscopic, immunohistochemical (Inducible nitric oxide synthase [iNOS] and alpha-smooth muscle actin [α-SMA]), real-time polymerase chain reaction (gene expression of TNF-α, interleukin-6, Bax, BCL-2, and caspase 3), histomorphometric analysis and oxidative/antioxidative markers (thiobarbituric acid reactive substances [TBARS], malondialdehyde [MDA]/glutathione [GSH] and superoxide dismutase [SOD]) were done.

RESULTS: The HFD, HFruD and HFHF groups developed a cluster of liver disorders; steatosis, necrosis, inflammation, apoptosis, ballooning degeneration and cytopla- smic vacuolations. Internal metabolic impairments include elevated serum levels of glucose, triglycerides, low density lipoprotein and decreased serum levels of high density lipoprotein and albumin. The immunoreaction of the α-SMA and iNOS was strong in these groups. The oxidant markers (MDA and TBARS) were elevated, while the antioxidant markers (SOD and GSH) were decreased. The area per cent of collagen, inflammatory markers, caspase 3 and Bax were elevated, while the BCL-2/Bax ratio was decreased. The decrease in PAS, antioxidant markers and the elevation of the α-SMA, iNOS, inflammatory and oxidant markers were obvious in the HFHF when compared to that of the other groups.

CONCLUSIONS: High-fat diet, HFruD, and HFHF developed morphologic hepatic changes ranging from steatosis to necrosis and inflammation, besides the deve- lopment of internal metabolic impairments. The chief factors of hepatic injury were fat accumulation in the hepatocytes, oxidative stress and highly elevated iNOS. Compared to the other groups, HFHF's effect was more prominent.

Zaki, S. M., S. A. Fattah, and D. S. Hassan, "The differential effects of high-fat and high fructose diets on the liver of male albino rat and the proposed underlying mechanisms.", Folia morphologica, 2018 Jul 16. Abstract

BACKGROUND: The western-style diet is characterized by the high intake of energy-dense foods. Consumption of either high fructose diet or saturated fat resulted in the development of metabolic syndrome. Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome. Many researchers studied the effect of high-fat diet (HFD), high fructose diet (HFruD) and high fructose high-fat diet (HFHF) on the liver. The missing data are the comparison effect of these groups i.e. are effects of the HFHF diet on the liver more pronounced? So, this study was designed to compare the metabolic and histopathological effect of the HFD, HFruD, and HFHF on the liver. The proposed underlying mechanisms involved in these changes were also studied.

MATERIALS AND METHODS: 24 rats were divided into four groups: control, HFD, HFruD, and HFHF. Food was offered for 6 weeks. Biochemical, light microscopic, immunohistochemical { Inducible nitric oxide synthase (iNOS) and alpha-smooth muscle actin (α-SMA)}, Real-time PCR (gene expression of TNF-α, IL-6, Bax, BCL2, and caspase 3), histomorphometric analysis and oxidative/antioxidative markers {thiobarbituric acid reactive substances (TBARS), malondialdehyde (MDA)/glutathione (GSH) and superoxide dismutase (SOD)} were done.

RESULTS: The HFD, HFruD and HFHF groups developed a cluster of liver disorders; steatosis, necrosis, inflammation, apoptosis, ballooning degeneration and cytoplasmic vacuolations. Internal metabolic impairments include elevated the serum levels of glucose, triglycerides, LDL and decreased the serum levels of HDL and albumin. The immunoreaction of the α-SMA and iNOS was strong in these groups. The oxidant markers (MDA and TBARS) were elevated, while the antioxidant markers (SOD and GSH) were decreased. The area % of collagen, inflammatory markers, caspase 3 and Bax elevated, while the BCL-2/Bax ratio decreased. The decrease of PAS, antioxidant markers and the elevation of the α-SMA, iNOS, inflammatory and oxidant markers were obvious in the HFHF when compared to that of the other groups.

CONCLUSIONS: HFD, HFruD, and HFHF developed morphologic hepatic changes ranging from steatosis to necrosis and inflammation, besides the development of internal metabolic impairments. The chief factors of hepatic injury were fat accumulation in the hepatocytes, oxidative stress and highly elevated iNOS. Compared to the other groups, HFHF's effect was more prominent.

Zaki, M. S., S. N. Saleem, W. B. Dobyns, A. J. Barkovich, H. Bartsch, A. M. Dale, M. Ashtari, N. Akizu, J. G. Gleeson, and A. M. Grijalvo-Perez, "Diencephalic–mesencephalic junction dysplasia: a novel recessive brain malformation", Brain, vol. 135, no. 8: Oxford University Press, pp. 2416–2427, 2012. Abstract

We describe six cases from three unrelated consanguineous Egyptian families with a novel characteristic brain malformation at the level of the diencephalic–mesencephalic junction. Brain magnetic resonance imaging demonstrated a dysplasia of the diencephalic–mesencephalic junction with a characteristic ‘butterfly’-like contour of the midbrain on axial sections. Additional imaging features included variable degrees of supratentorial ventricular dilatation and hypoplasia to complete agenesis of the corpus callosum. Diffusion tensor imaging showed diffuse hypomyelination and lack of an identifiable corticospinal tract. All patients displayed severe cognitive impairment, post-natal progressive microcephaly, axial hypotonia, spastic quadriparesis and seizures. Autistic features were noted in older cases. Talipes equinovarus, non-obstructive cardiomyopathy and persistent hyperplastic primary vitreous were additional findings in two families. One of the patients required shunting for hydrocephalus; however, this yielded no change in ventricular size suggestive of dysplasia rather than obstruction. We propose the term ‘diencephalic–mesencephalic junction dysplasia’ to characterize this autosomal recessive malformation.

Zaki, S. A., G. M. El-Kherbawy, A. A. Ayad, and D. A. Gad El-Rab, "Developing Functional Cereal Flakes with Probiotics", 23rd International ICFMH Symposium Food Micro 2012, 3-7 September, 2012, Istanbul, Turkey: ICFMH, 2012. Abstract
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Zaki, S. A., H. Zhu, M. A. Fakih, A. R. Sayed, and J. Yao, "Deep‐learning–based method for faults classification of PV system", IET Renewable Power Generation, vol. 15, issue 1, pp. 193-205, 2021. Abstract
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Zaki, S. A., H. Zhu, J. Yao, A. R. Sayed, and M. A. Abdelbaky, "Detection and localization the open and short circuit faults in PV system: A MILP approach", 2020 Asia Energy and Electrical Engineering Symposium (AEEES): IEEE, pp. 187–193, 2020. Abstract
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