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Zekri, A. - R. N., A. A. - M. Nassar, M. N. E. - D. El-Rouby, H. I. Shousha, A. B. Barakat, E. D. El-Desouky, N. A. Zayed, O. S. Ahmed, A. S. E. - D. Youssef, A. O. Kaseb, et al., "Disease Progression from Chronic Hepatitis C to Cirrhosis and Hepatocellular Carcinoma is Associated with Increasing DNA Promoter Methylation. ", Asian Pacific Journal of Cancer Prevention, vol. 14, pp. 6721-6726, 2013.
Zekri, A. R., A. A. Nassar, M. N. Elrouby, H. I. Shousha, and A. B. Barakat, "Disease progression from chronic hepatitis C to cirrhosis and hepatocellular carcinoma is associated with increasing DNA promoter methylation", Asian Pac J Cancer Prev., vol. 14, issue 11, pp. 6721-6, 2014.
Zekri, A. - R. N., Z. K. Hassan, A. A. Bahnassy, H. M. Khaled, M. N. El-Rouby, R. M. Haggag, and F. O. U. A. D. M. ABU-TALEB, "Differentially expressed genes in metastatic advanced Egyptian bladder cancer.", Asian Pacific journal of cancer prevention : APJCP, vol. 16, issue 8, pp. 3543-9, 2015. Abstract

BACKGROUND: Bladder cancer is one of the most common cancers worldwide. Gene expression profiling using microarray technologies improves the understanding of cancer biology. The aim of this study was to determine the gene expression profile in Egyptian bladder cancer patients.

MATERIALS AND METHODS: Samples from 29 human bladder cancers and adjacent non-neoplastic tissues were analyzed by cDNA microarray, with hierarchical clustering and multidimensional analysis.

RESULTS: Five hundred and sixteen genes were differentially expressed of which SOS1, HDAC2, PLXNC1, GTSE1, ULK2, IRS2, ABCA12, TOP3A, HES1, and SRP68 genes were involved in 33 different pathways. The most frequently detected genes were: SOS1 in 20 different pathways; HDAC2 in 5 different pathways; IRS2 in 3 different pathways. There were 388 down-regulated genes. PLCB2 was involved in 11 different pathways, MDM2 in 9 pathways, FZD4 in 5 pathways, p15 and FGF12 in 4 pathways, POLE2 in 3 pathways, and MCM4 and POLR2E in 2 pathways. Thirty genes showed significant differences between transitional cell cancer (TCC) and squamous cell cancer (SCC) samples. Unsupervised cluster analysis of DNA microarray data revealed a clear distinction between low and high grade tumors. In addition 26 genes showed significant differences between low and high tumor stages, including fragile histidine triad, Ras and sialyltransferase 8 (alpha) and 16 showed significant differences between low and high tumor grades, like methionine adenosyl transferase II, beta.

CONCLUSIONS: The present study identified some genes, that can be used as molecular biomarkers or target genes in Egyptian bladder cancer patients.

Zekkos, D., N. Matasovic, R. El-Sherbiny, A. Athanasopoulos-Zekkos, I. Towhata, and M. Maugeri, "Dynamic properties of municipal solid waste", GEOTECHNICAL SPECIAL PUBLICATION, vol. 209, pp. 113, 2008. Abstract
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Zeini, N. T., "Diagnose the viability of separation of power in Egypt: a cybernetics perspective", Kybernetes, vol. 52, issue 4, pp. 1351-1369, 2023.
Zein, H., and H. Omar, "Designing and Manufacturing of Miniature Savonius Wind ‎Turbine", International Engineering Conference and Exhibition IECE‎, Riyadh, Saudi Arabia‎, 5 December, 2017. 4th_paper.pdf
Zeid, F. A., and H. Kuhn, "Der Einfluss von Kieselsaure auf die Halmstabilitat von Getride.", Zeitschrift für Landwirtschaftliche Forschung,, vol. 26, pp. 105–111, 1971. Abstract
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Zeid, F. A., and H. Kuhn, "Der Einfluss von Kieselsaure auf die Halmstabilitat von Getride.", Zeitschrift für Landwirtschaftliche Forschung,, vol. 26, pp. 105–111, 1971. Abstract
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Zeeneldin, A. A., A. A. Gaber, and F. M. Taha, "Does fasting during Ramadan trigger non-adherence to oral hormonal therapy in breast cancer patients?", Journal of the Egyptian National Cancer Institute, vol. 24, issue 3, pp. 133-7, 2012 Sep. Abstract

PURPOSE: To estimate the effect of fasting during Ramadan (the ninth lunar month) on adherence to oral hormonal therapies (OHT) among breast cancer (BC) patients.

PATIENTS AND METHODS: During Ramadan 2010, 139 BC patients were interviewed at the Egyptian National Cancer Institute. They were asked about fasting as well as intake of OHT in Ramadan and in the preceding month.

RESULTS: The median age was 50years and most patients were postmenopausal with good performance status and non-metastatic disease. The median number of fasting days was 18% and 93% of patients were fasting 80% or more of Ramadan. Tamoxifen and aromatase inhibitors were used in 64% and 36%, respectively. Adherence to OHT during Ramadan and its preceding month were 94.2% and 95.7%, respectively (p=0.77). In univariate analysis, non-adherence prior to Ramadan and shorter duration of OHT were predictors of non-adherence during Ramadan (P<0.001, 0.003, respectively). Fasting, age, performance status, presence of metastases and type of hormonal therapy were not good predictors of adherence.

CONCLUSIONS: While most of patients receiving OHT for BC are fasting during Ramadan, this does not negatively impact compliance with treatment.

Zeeneldin, A., N. Gad Elmawla, A. Elkhodary, and N. Allahloubi, Dose-dense chemotherapy versus conventional chemotyherapy as primary therapy in advanced breast cancer, , Cairo, Cairo, 2001.
Zeeneldin, A. A., A. A. Gaber, and F. M. Taha, "Does fasting during Ramadan trigger non-adherence to oral hormonal therapy in breast cancer patients?", Journal of the Egyptian National Cancer Institute: Elsevier, 2012. Abstract
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Zayed, R. A., D. Omran, A. A. Zayed, and L. O. Elmessery, Determinants of infection outcome in HCV genotype- 4, , 2017.
Zayed, A., A. A. Awash, M. A. Esmail, H. A. Al-Mohamadi, M. Al-Salwai, A. Al-Jasari, I. Medhat, M. E. Morales-Betoulle, and A. Mnzava, "Detection of Chikungunya virus in Aedes aegypti during 2011 outbreak in Al Hodayda, Yemen", Acta tropica, vol. 123, no. 1: Elsevier, pp. 62–66, 2012. Abstract
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Zayed, R. A., D. Omran, A. A. Zayed, and L. O. Elmessery, "Determinants of Infection Outcome in HCV-genotype 4", Viral Immunology, vol. 30 , issue 8, pp. 560-567, 2017.
Zayed, R. A., E. Rushdy, and D. ’aA. Saleh, "Detection of HCV RNA in the Peripheral Blood Mononuclear Cells of Serum HCV RNA Negative Egyptian Patients under Interferon Treatment.", Am J Med Sci., vol. 340, issue 6, pp. 435-438, 2010. Abstract

INTRODUCTION:
Despite recent success after the introduction of combination therapy with interferon (IFN)-α and ribavirin, approximately 60% of patients with hepatitis C virus (HCV) genotype 4 fail to respond. Resistance to antiviral therapy remains a serious problem in the management of chronic hepatitis C. In most patients, HCV RNA could be detected in peripheral blood mononuclear cell (PBMC).
OBJECTIVE:
The authors aimed to investigate the predictive value of HCV RNA in PBMC of patients with chronic hepatitis C after IFN treatment, which may act as the source of HCV reinfection of hepatic cells.
METHODS:
Seventy patients with chronic hepatitis C were treated with IFN plus ribavirin for 48 weeks; they all achieved clearance of HCV RNA from serum. At the end of treatment, PBMC and serum were examined by real-time polymerase chain reaction for detection of HCV RNA. Six months later, HCV RNA in serum was monitored to detect sustained virologic response.
RESULTS:
: Analysis revealed the presence of detectable HCV RNA in the PBMC of 27% of patients despite clearance of serum HCV RNA. During follow-up, 80% of the patients who became serum HCV positive 6 months after the end of treatment had detectable level of HCV RNA in PBMC at the end of treatment.
CONCLUSIONS:
The absence of HCV in the serum of patients by the end of treatment does not exclude future viremia. The patient might still be a source of infection to others. It is strongly encouraged to test for HCV in PBMC to detect lack of response to treatment and persisting infection.

Zayat, D. A. L. M., E. M. Attalla, H.S.Abouelenein, and M. A. Elnaggar, "Dosimetric comparison of Intensity-modulated radiotherapy versus 3D conformal radiotherapy in patients with prostate and pancreatic cancer", The Journal of Radiology. Photon, vol. 125, pp. 142-155, 2014. imrtversus_3dc__prostate__pancreatic_cancer.pdf
Zayat, D. A. L. M., E. M. Attalla, H.S.Abouelenein, and W. Khalil, "Dosimetric Comparison of Intensity-Modulated Radiotherapy versus 3D Conformal Radiotherapy in Patients with Head and Neck Cancer", Journal of Multidisciplinary Engineering Science and Technology (JMEST), vol. Vol. 2, issue Issue 4, pp. 678-682, 2015. dosimetric_comparison_of_imrt_vs_3dc_hn.pdf
Zayat, D. M. A. L., E. M. Attalla, H. S. Abouelenein, and Y. M. Elkerm, "Dosimetric comparison of Intensity-modulated radiotherapy versus three dimensional conformal radiotherapy for patients with brain tumors. ", Open Journal of Radiology, vol. 4, issue 1, pp. 85-96, 2014. dosimetric_comparison_of.pdf
Zawilla, N. H., A. A. M. Mohammad, N. M. El Kousy, and S. M. E. - M. Aly, "Determination of aceclofenac in bulk and pharmaceutical formulations", Journal of pharmaceutical and biomedical analysis, vol. 27, issue 1-2, pp. 243-251, 2002.
Zawilla, N. H., A. - A. M. Mohammad, and S. M. E. - M. Aly, "Determination of meloxicam in bulk and pharmaceutical formulations", Journal of pharmaceutical and biomedical analysis, vol. 32, issue 6, pp. 1135-1144, 2003.
Zawilla, N. H., A. - A. M. Mohammad, S. M. E. - M. Aly, and others, "Determination of meloxicam in bulk and pharmaceutical formulations", Journal of pharmaceutical and biomedical analysis, vol. 32, no. 6: Elsevier, pp. 1135–1144, 2003. Abstract
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Zarif, P., A. A. A. Mahmoud, M. M. Abdelhaq, H. M. S.Mikhail, and A. Farag, "Dexmedetomidine versus Magnesium Sulfate as Adjunct during Anesthesia for Laparoscopic Colectomy", Anesthesiology Research and Practice, 2016.