Publications

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2011
Sakr, S., E. Pascalau, A. Awad, and M. Weske, "BPModelMasher: Manage Your Process Variants Effectively", Proceedings of the Demo Track of the Nineth Conference on Business Process Management 2011, Clermont-Ferrand, France, August 31st, 2011, 2011. Abstract
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Xiao, K., A. E. Hassanien, Y. Sun, and E. K. K. Ng, "Brain mr image tumor segmentation with ventricular deformation", Image and Graphics (ICIG), 2011 Sixth International Conference on: IEEE, pp. 297–302, 2011. Abstract
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Xiao, K., A. E. Hassanien, Y. Sun, and E. K. K. Ng, "Brain mr image tumor segmentation with ventricular deformation", Image and Graphics (ICIG), 2011 Sixth International Conference on: IEEE, pp. 297–302, 2011. Abstract
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Mohammed, R. H. A., Y. Y. Sabry, and A. A. Nasef, "Brain MRI screening showing evidences of early central nervous system involvement in patients with systemic sclerosis.", Rheumatology international, vol. 31, issue 5, pp. 667-71, 2011. Abstract

Systemic sclerosis is a multisystem autoimmune collagen disease where structural and functional abnormalities of small blood vessels prevail. Transient ischemic attacks, ischemic stroke, and hemorrhage have been reported as primary consequence of vascular central nervous system affection in systemic sclerosis. Magnetic resonance imaging is considered to be the most sensitive diagnostic technique for detecting symptomatic and asymptomatic lesions in the brain in cases of multifocal diseases. The objective of this study is to detect subclinical as well as clinically manifest cerebral vasculopathy in patients with systemic sclerosis using magnetic resonance imaging. As much as 30 female patients with systemic sclerosis aged 27-61 years old, with disease duration of 1-9 years and with no history of other systemic disease or cerebrovascular accidents, were enrolled. Age-matched female control group of 30 clinically normal subjects, underwent brain magnetic resonance examination. Central nervous system (CNS) involvement in the form of white matter hyperintense foci of variable sizes were found in significantly abundant forms in systemic sclerosis patients on magnetic resonance evaluation than in age-related control group, signifying a form of CNS vasculopathy. Such foci showed significant correlation to clinical features of organic CNS lesion including headaches, fainting attacks and organic depression as well as to the severity of peripheral vascular disease with insignificant correlation with disease duration. In conclusion, subclinical as well as clinically manifest CNS ischemic vasculopathy is not uncommon in systemic sclerosis patients and magnetic resonance imaging is considered a sensitive noninvasive screening tool for early detection of CNS involvement in patients with systemic sclerosis.

Yip, C. - H. a, E. b Cazap, B. O. c d Anderson, K. L. e Bright, M. f Caleffi, F. g h Cardoso, A. M. i Elzawawy, J. B. j Harford, G. D. k l Krygier, S. m Masood, et al., "Breast cancer management in middle-resource countries (MRCs): Consensus statement from the Breast Health Global Initiative", Breast, vol. 20, no. SUPPL. 2, pp. S12-S19, 2011. AbstractWebsite

In middle resource countries (MRCs), cancer control programs are becoming a priority as the pattern of disease shifts from infectious diseases to non-communicable diseases such as breast cancer, the most common cancer among women in MRCs. The Middle Resource Scenarios Working Group of the BHGI 2010 Global Summit met to identify common issues and obstacles to breast cancer detection, diagnosis and treatment in MRCs. They concluded that breast cancer early detection programs continue to be important, should include clinical breast examination (CBE) with or without mammography, and should be coupled with active awareness programs. Mammographic screening is usually opportunistic and early detection programs are often hampered by logistical and financial problems, as well as socio-cultural barriers, despite improved public educational efforts. Although multidisciplinary services for treatment are available, geographical and economic limitations to these services can lead to an inequity in health care access. Without adequate health insurance coverage, limited personal finances can be a significant barrier to care for many patients. Despite the improved availability of services (surgery, pathology, radiology and radiotherapy), quality assurance programs remain a challenge. Better access to anticancer drugs is needed to improve outcomes, as are rehabilitation programs for survivors. Focused and sustained government health care financing in MRCs is needed to improve early detection and treatment of breast cancer. © 2011 Elsevier Ltd.

et el 52- Rashwan, M., "Building an Arabic lexical Semantic Analyzer;", 7th International Computing Conference in Arabic (ICCA2011), Riyadh, KSA., 2011. Abstract
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-, A. R., M. Kunze, A. Awad, and M. Weske, "Business Process Configuration Wizard and Consistency Checker for {BPMN} 2.0", Enterprise, Business-Process and Information Systems Modeling - 12th International Conference, {BPMDS} 2011, and 16th International Conference, {EMMSAD} 2011, held at CAiSE 2011, London, UK, June 20-21, 2011. Proceedings, pp. 231–245, 2011. Abstract
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Soltana, A., A. G. Radwanb, and A. M. Solimand, "Butterworth Passive Filter in the Fractional-Order", Microelectronics (ICM), 2011 International Conference, 2011. Abstract
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Soltana, A., A. G. Radwanb, and A. M. Solimand, "Butterworth Passive Filter in the Fractional-Order", Microelectronics (ICM), 2011 International Conference, 2011. Abstract
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2010
Ramadan, H. M., "Buckling Analysis of Vertically Curved Box Profiles Subjected to In-plane Moments", 6th International Engineering and Construction Conference (IECC'6), AISC, Cairo, Egypt, June, 2010.
Macky, T. A., "Bimatoprost versus travoprost in an Egyptian population: a hospital-based prospective, randomized study.", Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, vol. 26, issue 6, pp. 605-10, 2010 Dec. Abstract

PURPOSE: To compare the efficacy of bimatoprost and travoprost on intraocular pressure (IOP) reduction in an Egyptian population.

METHODS: Patients with primary open-angle glaucoma or ocular hypertension were randomized to receive either bimatoprost 0.03% or travoprost 0.004% once daily. IOPs were measured at baseline; 2 weeks; and 1, 2, 4, and 6 months using Goldman applanation tonometery.

RESULTS: Seventy-two patients were included: 34 and 38 (P = 0.142) with a baseline mean IOP = 26.52 ± 5.185 and 26.36 ± 1.605 mm Hg (P = 0.629) for bimatoprost and travoprost, respectively. Both drops provided statistically significant IOP reductions from baseline at all visits (P < 0.001). Bimatoprost provided greater (nonsignificant) mean IOP reductions from baseline than travoprost at each visit. Mean IOP reductions was 8.77 mm Hg (33.39%) and 8.42 mm Hg (31.54%) at 2 weeks (P = 0.703), and 8.47 mm Hg (31.61%) and 7.84 mm Hg (29.50%) at 6 months (P = 0.536) for bimatoprost and travoprost, respectively. IOPs at 2 weeks were ≤18 mm Hg in 20 (58.8%) versus 19 (50%) eyes (P = 0.603), and ≤16 mm Hg in 12 (35%) versus 12 (32%) eyes (P = 0.456); and at 6 months ≤18 mm Hg in 22 (65%) versus 14 (37%) eyes (P = 0.045), and ≤16 mm Hg in 12 (35%) versus 7 (18%) eyes (P = 0.037) for bimatoprost and travoprost, respectively. Ocular adverse and clinical success occurred equally with both drops.

CONCLUSION: Both drops lowered IOP effectively but bimatoprost showed a greater non-significant reductions in mean IOP from baseline.

Amer, A., H. Rakha, and I. El-Shawarby, "A Behavioral Modeling Framework of Driver Behavior at Onset of Yellow Indication at Signalized Intersections", Transportation Research Board 89th Annual Meeting, Washington, DC, 2010. Abstract
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Ahmed, M. A., N. Okasha, S. F. Mansour, and S. I. El-dek, "Bi-modal improvement of the physico-chemical characteristics of PEG and MFe2O4 subnanoferrite", Journal of Alloys and Compounds, vol. 496, issue 1-2, pp. 345 - 350, 2010. AbstractWebsite

MFe2O4 (M = Mn2+, Ni2+, Co2+ and Cu2+) ferrite powders were prepared by flash auto-combustion reaction. The structural identification of the samples was carried out using X-ray diffraction (XRD), transmission electron microscope (TEM), selected area electron diffraction (SAED) and IR spectra. The study established the formation of sub-nanosized particles especially for MFe2O4 (M = Ni, Co and Cu) ferrites. MFe2O4/PEG (polyethylene glycol) composites were prepared by cold uniaxial pressing. The magnetic properties were studied by carrying out the hysteresis of MFe2O4 and PEG/MFe2O4 composite at room temperature. The data showed that MnFe2O4 has the highest saturation magnetization while CoFe2O4 has the largest coercive field due to the high anisotropy of Co2+ ions. The ac electrical conductivity as well as the dielectric constant ε′ and loss tangent tan δ were measured at different frequencies at room temperature. The highest conductivity is achieved for PEG/Ni Fe2O4 and the lowest value of tan δ is obtained for PEG/MnFe2O4 amongst all PEG/MFe2O4 nanocomposites. © 2010 Elsevier B.V. All rights reserved.

Hussein, M. M., S. M. Metwalli, A. - N. A. Mohamed, and A. A. Shabana, "BELT DRIVE MECHANICS WITH ABSOLUTE NODAL COORDINATE FINITE ELEMENT VERIFICATION", ASME 2010 International Mechanical Engineering Congress & Exposition, Vancouver, British Colombia, Canada, 12-18 November, 2010.
Ismail, I. H., C. Andrin, D. McDonald, and M. J. Hendzel, "BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair.", J Cell Biol, vol. 191, no. 1, United States, pp. 45-60, 10, 2010. Abstract

Polycomb group (PcG) proteins are major determinants of cell identity, stem cell pluripotency, and epigenetic gene silencing during development. The polycomb repressive complex 1, which contains BMI1, RING1, and RING2, functions as an E3-ubuiquitin ligase. We found that BMI1 and RING2 are recruited to sites of DNA double-strand breaks (DSBs) where they contribute to the ubiquitylation of $\gamma$-H2AX. In the absence of BMI1, several proteins dependent on ubiquitin signaling, including 53BP1, BRCA1, and RAP80, are impaired in recruitment to DSBs. Loss of BMI1 sensitizes cells to ionizing radiation to the same extent as loss of RNF8. The simultaneous depletion of both proteins revealed an additive increase in radiation sensitivity. These data uncover an unexpected link between the polycomb and the DNA damage response pathways, and suggest a novel function for BMI1 in maintaining genomic stability

AHMED, A. A., P. Leinweber, and O. Kühn, "Binding of chlorinated environmentally active chemicals to soil surfaces: chromatographic measurements and molecular dynamics simulations", 2nd Interdisciplinary Scientific Seminar, Rostock-Warnemünde, March 25, 2010.
Abdou, N. - E. M. I., and M. Y. Abdou, "Bacterial Conjunctivitis in Cattle and Antibiotic Sensitivity of the Isolates", Research Journal of Animal and Veterinary Sciences, vol. 5, pp. 38-42, 2010. bacterial_conjunctivitis_2010.pdf
M. Moustafa, Laila. A. Mohamed, M. A. Mahmoud, and E. -gendyM. Y. W.S. Soliman, "Bacterial Infections Affecting Marine Fishes in Egypt", Journal of American Science , vol. 6, no.11, pp. 603-612, 2010. Abstract

Some fish species are suffering from continuous depletion due to devastating environmental changes at their native aquatic environment. Qarun Lake and Suez Gulf are among the most vulnerable areas. Thus, representative fish samples from those areas were inspected for the presence of any fish pathogenic bacteria. The inspected samples included six different species; Epinephelus tuvina, Siganus rivulatus, and Dedlechilus labiosus native to Suez Gulf at Suez governorate; Tilapia zilli, Mugil capito and Solea vulgaris native to Qarun Lake at El- Fayoum governorate. A total of 600 samples were examined throughout the different year seasons. Gram positive and negative fish pathogenic bacteria were isolated from a total of 245 fish sample. Among those samples, the following bacteria were retrieved in the following percentages respectively, 17.55% (V. anguillarum), 16.73% (V. alginolyticus), 15.51% (P. piscicida), 15.91% (Ps. fluorescens), 13.46% (S. fecalis), 11.02% (A. hydrophila), 6.12% (A. sobria) and 3.67% were infected with Staph. aureus. The Siganus rivulatus was the highest infected fish species with a prevalence of 8.33%, while Mugil capito was the lowest infected species (5.67 %). The highest total prevalence of bacterial infection was recorded in summer season (40.81%) while the lowest was recorded in winter (15.91%). The aforementioned bacterial isolates were successfully re-isolated from experimentally infected fish. The retrieved isolates were matched against standard isolates as well as confirmed to be positive using semi- automated (API 20 E) and conventional biochemical tests.

Moustafa, M., M. A. Laila, M. A. Mahmoud, and -gendyM. E. Y. W. S. Soliman, "Bacterial Infections Affecting Marine Fishes in Egypt", Journal of American Science , , , vol. vol. 6, no.11, pp. 603-612, 2010. Abstract

Some fish species are suffering from continuous depletion due to devastating environmental changes at their native aquatic environment. Qarun Lake and Suez Gulf are among the most vulnerable areas. Thus, representative fish samples from those areas were inspected for the presence of any fish pathogenic bacteria. The inspected samples included six different species; Epinephelus tuvina, Siganus rivulatus, and Dedlechilus labiosus native to Suez Gulf at Suez governorate; Tilapia zilli, Mugil capito and Solea vulgaris native to Qarun Lake at El- Fayoum governorate. A total of 600 samples were examined throughout the different year seasons. Gram positive and negative fish pathogenic bacteria were isolated from a total of 245 fish sample. Among those samples, the following bacteria were retrieved in the following percentages respectively, 17.55% (V. anguillarum), 16.73% (V. alginolyticus), 15.51% (P. piscicida), 15.91% (Ps. fluorescens), 13.46% (S. fecalis), 11.02% (A. hydrophila), 6.12% (A. sobria) and 3.67% were infected with Staph. aureus. The Siganus rivulatus was the highest infected fish species with a prevalence of 8.33%, while Mugil capito was the lowest infected species (5.67 %). The highest total prevalence of bacterial infection was recorded in summer season (40.81%) while the lowest was recorded in winter (15.91%). The aforementioned bacterial isolates were successfully re-isolated from experimentally infected fish. The retrieved isolates were matched against standard isolates as well as confirmed to be positive using semi- automated (API 20 E) and conventional biochemical tests.

Moustafa, M., AM Laila, A. M. Mahmoud, WS Soliman, and M. Y. El-Gendy, "Bacterial Infections Affecting Marine Fishes in Egypt", Journal of American Science, vol. 6, issue 11, pp. 603-612, 2010. bacterial_infections_affecting_marine_fishes_in_egypt.pdf
Hadidi, E. N. M. N., and R. Hamdy, "Basketry accessories: footwear, bags and fans in ancient Egypt", Journal of Archaeological Science (07 December 2010, 2010. CU-PDF.pdf
Hadidi, E. N. M. N., and R. S. Hamdy, "Basketry accessories: footwear, bags and fans in ancient Egypt", Journal of Archaeological Science , vol. 30, pp. 1-12 , 2010.
D, M., E. - E. N, E. - T. AM, and B. DA, "Bcl-2 expression in mycosis fungoides before and after PUVA therapy", Photodermatol Photoimmunol Photomed, vol. 26, issue 2, pp. 107-9, 2010. Abstract

PUVA is the first therapeutic choice in early stages of mycosis fungoides (MF). In this study the effect of PUVA on bcl-2 expression in MF was assessed in 15 patients (three stage Ia and 12 stage Ib) and 10 controls. Two biopsies were taken from each patient before and after 24 sessions of PUVA therapy. Histopathological assessment and immunohistochemical staining for bcl-2 was performed and showed positive bcl-2 staining of lymphocytes in 53% of MF cases (8/15) before PUVA, with no statistically significant difference in the bcl-2 level before and after PUVA therapy (P value 0.3). A statistically significant difference was found in the bcl-2 level between control samples and MF patients’ biopsies before (P value 0.02) and after PUVA therapy (P value 0.011). In conclusion, a lack of decline in the bcl-2 level and the absence of clinical or histopathological correlation with the bcl-2 level before and after PUVA therapy in MF patients suggest that PUVA-induced apoptosis in MF cases may occur through
pathways other than bcl-2 inhibition.

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