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EM El-Sayed, SM Badran, A. M. H. A. A. M., "Behavior and fate of polychlorinated biphnels during processing of some dairy products", Bulletin of the international Dairy Federation, vol. 472: Bulletin of the international Dairy Federation, pp. 55-65, 2014. Abstract
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Hamada, A. K., M. Z. Rashad, and M. G. Darwesh, "Behavior analysis in a learning environment to identify the suitable learning style", International Journal of Computer Science & Information Technology (IJCSIT), vol. 3, no. 2, pp. 48–59, 2011. Abstract
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Mostafa, H., M. El-Ramly, A. Elkorany, and H. Shaban, "behavio2auth : Sensor-based Behavior Biometric Authentication for Smartphones", 6th annual international conference on arabwoman computing, Morroco, March, 2019.
Kapiel, T., "Beginning of a new era of artificial life", Al Masry Elyoum, vol. 4323, 2016. Abstract

بداية عصر جديد للحياة الاصطناعية
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Beginning of a new era of artificial life

Amer, A., and W. Zhang, "Before And After Operational Assessment Of Mini-Roundabout Success Stories", 5th International Road Safety and Simulation (RSS 2015), Orlando, FL, University of Central Florida (UCF)University of Tennessee, Knoxville (UTK) , pp. 12, 2015. Abstract
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Abdel-Salam, A.M., E. - S. M. A., and H. S. Abdelkader, "Beet necrotic ringspot virus, a new ilarvirus infecting sugarbeet in Egypt. Biological, biochemical, serological, and genomic studies", Arab J. Biotech., vol. 9, no. (2), pp. 395–414, 2006. Abstract
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Hala A.H. Khattab, I. Z. A. Abdallah, and K. A. Ahmed., "Bees honey abolishes the physiological disorders induced by some synthetic food colourant additives administered to young male albino rats", Med. J. Cairo Univ., Vol., vol. 73, No. 2, pp. 111- 126., 2005.
Jallon, J. M., Y. Risler, and M. Iwatsubo, "Beef liver L-Glutamate dehydrogenase mechanism: presteady state study of the catalytic reduction of 2.oxoglutarate by NADPH.", Biochemical and biophysical research communications, vol. 67, issue 4, pp. 1527-36, 1975 Dec 15. Abstract
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, "bee venom loaded chitosan nanoparticles as treatment for amoebiasis in mice", journal of the Egyptian society of parasitology, vol. 47(2), issue 1110-0583, pp. 443-458, 2017.
ZOH, H. U. S. S. E. I. N. F. O. U. A. D., A. M. E. Amir, A. M. A. N. Y. E. L. S. A. Y. E. D. SABER, A. B. D. E. L. W. A. H. A. B. K. H. A. L. I. L. ABDELWAHAB, and M. I. Nassar, "BEE VENOM LOADED CHITOSAN NANOPARTICLES AS TREATMENT FOR AMOEBIASIS IN MICE", Journal of the egyptian society of parasitology, vol. 47, issue 2, pp. 607-616, 2017.
Nassar, M. I., D. I. N. A. H. ABD EL-MONEM, M. Youssef, S. A. M. A. R. M. IBRAHIM, S. O. H. A. M. MOHAMED, M. O. H. M. E. D. S. A. L. A. H. ABD-ALDAYEM, and E. M. A. N. A. L. A. A. E. L. D. I. N. ABDELFATTAH, "Bee venom drug potentiality on the macromolecules damage of the larval gut of hermetia illucens (l.),(diptera: stratiomyidae)", Journal of the Egyptian Society of Parasitology, vol. 50, no. 3: The Egyptian Society of Parasitology, pp. 488–493, 2020. Abstract
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Nassar, M. I., D. I. N. A. H. ABD EL-MONEM, M. Youssef, S. A. M. A. R. M. IBRAHIM, S. O. H. A. M. MOHAMED, M. O. H. M. E. D. S. A. L. A. H. ABD-ALDAYEM, and E. M. A. N. A. L. A. A. E. L. D. I. N. ABDELFATTAH, "Bee venom drug potentiality on the macromolecules damage of the larval gut of hermetia illucens (l.),(diptera: stratiomyidae)", Journal of the Egyptian Society of Parasitology, vol. 50, no. 3: The Egyptian Society of Parasitology, pp. 488–493, 2020. Abstract
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Nassar, M. I., D. I. N. A. H. ABD EL-MONEM, M. Youssef, S. A. M. A. R. M. IBRAHIM, S. O. H. A. M. MOHAMED, M. O. H. M. E. D. S. A. L. A. H. ABD-ALDAYEM, and E. M. A. N. A. L. A. A. E. L. D. I. N. ABDELFATTAH, "Bee venom drug potentiality on the macromolecules damage of the larval gut of hermetia illucens (l.),(diptera: stratiomyidae)", Journal of the Egyptian Society of Parasitology, vol. 50, no. 3: The Egyptian Society of Parasitology, pp. 488–493, 2020. Abstract
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Nassar, M. I., D. I. N. A. H. ABD EL-MONEM, M. Youssef, S. A. M. A. R. M. IBRAHIM, S. O. H. A. M. MOHAMED, M. O. H. M. E. D. S. A. L. A. H. ABD-ALDAYEM, and E. M. A. N. A. L. A. A. E. L. D. I. N. ABDELFATTAH, "Bee venom drug potentiality on the macromolecules damage of the larval gut of hermetia illucens (l.),(diptera: stratiomyidae)", Journal of the Egyptian Society of Parasitology, vol. 50, no. 3: The Egyptian Society of Parasitology, pp. 488–493, 2020. Abstract
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Badawi, H. M., R. M. Abdelsalam, O. M. E. Abdel-Salam, E. R. Youness, N. M. Shaffie, and E. - E. D. S. Eldenshary, "Bee venom attenuates neurodegeneration and motor impairment and modulates the response to L-dopa or rasagiline in a mice model of Parkinson's disease.", Iranian journal of basic medical sciences, vol. 23, issue 12, pp. 1628-1638, 2020. Abstract

OBJECTIVES: This study aimed to investigate the effect of bee venom, a form of alternative therapy, on rotenone-induced Parkinson's disease (PD) in mice. Moreover, the possible modulation by bee venom of the effect of L-dopa/carbidopa or rasagiline was examined.

MATERIALS AND METHODS: Rotenone (1.5 mg/kg, subcutaneously; SC) was administered every other day for two weeks and at the same time mice received the vehicle (DMSO, SC), bee venom (0.065, 0.13, and 0.26 mg/kg; intradermal; ID), L-dopa/carbidopa (25 mg/kg, intraperitoneal; IP), L-dopa/carbidopa+bee venom (0.13 mg/kg, ID), rasagiline (1 mg/kg, IP) or rasagiline+bee venom (0.13 mg/kg, ID). Then, wire hanging and staircase tests were performed and mice were euthanized and brains' striata separated. Oxidative stress biomarkers namely, malondialdehyde (MDA), nitric oxide (NO), reduced glutathione (GSH), paraoxonase-1 (PON-1), and total antioxidant capacity (TAC) were measured. Additionally, butyrylcholinesterase (BuChE), monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-alpha (TNF-α), and dopamine (DA) were evaluated. Brain histopathological changes and caspase-3- expression were done.

RESULTS: Bee venom significantly enhanced motor performance and inhibited rotenone-induced oxidative/nitrosative stress, observed as a reduction in both MDA and NO along with increasing GSH, PON-1, and TAC. Besides, bee venom decreased MCP-1, TNF-α, and caspase-3 expression together with an increase in BuChE activity and DA content.

CONCLUSION: Bee venom alone or in combination with L-dopa/carbidopa or rasagiline alleviated neuronal degeneration compared with L-dopa/carbidopa or rasagiline treatment only. Bee venom via its antioxidant and cytokine reducing potentials might be of value either alone or as adjunctive therapy in the management of PD.

Mansour, G. H., M. A. El-Magd, D. H. Mahfouz, I. A. Abdelhamid, M. F. Mohamed, N. S. Ibrahim, A. H. A. A. Wahab, and E. M. Elzayat, "Bee venom and its active component Melittin synergistically potentiate the anticancer effect of Sorafenib against HepG2 cells", Bioorganic Chemistry, vol. 116, 2021.
Mansour, G. H., M. A. El-Magd, D. H. Mahfouz, I. A. Abdelhamid, M. F. Mohamed, N. S. Ibrahim, A. H. A. A. Wahab, and E. M. Elzayat, "Bee venom and its active component Melittin synergistically potentiate the anticancer effect of Sorafenib against HepG2 cells", Bioorganic Chemistry, vol. 116: Elsevier, pp. 105329, 2021. Abstract
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Mansour, G. H., M. A. El-Magd, D. H. Mahfouz, I. A. Abdelhamid, M. F. Mohamed, N. S. Ibrahim, A. Hady A. Abdel Wahab, and E. M. Elzayat, Bee venom and its active component Melittin synergistically potentiate the anticancer effect of Sorafenib against HepG2 cells, , vol. 116, pp. 105329, 2021. AbstractWebsite

There are current attempts to find a safe substitute or adjuvant for Sorafenib (Sorf), the standard treatment for advanced hepatocellular carcinoma (HCC), as it triggers very harsh side effects and drug-resistance. The therapeutic properties of Bee Venom (BV) and its active component, Melittin (Mel), make them suitable candidates as potential anti-cancer agents per-se or as adjuvants for cancer chemotherapy. Hence, this study aimed to evaluate the combining effect of BV and Mel with Sorf on HepG2 cells and to investigate their molecular mechanisms of action. Docking between Mel and different tumor-markers was performed. The cytotoxicity of BV, Mel and Sorf on HepG2 and THLE-2 cells was conducted. Combinations of BV/Sorf and Mel/Sorf were performed in non-constant ratios on HepG2. Expression of major cancer-related genes and oxidative stress status was evaluated and the cell cycle was analyzed. The computational analysis showed that Mel can bind to and inhibit XIAP, Bcl2, MDM2, CDK2 and MMP12. Single treatments of BV, Mel and Sorf on HepG2 showed lower IC50than on THLE-2. All combinations revealed a synergistic effect at a combination index (CI) < 1. Significant upregulation (p < 0.05) of p53, Bax, Cas3, Cas7 and PTEN and significant downregulation (p < 0.05) of Bcl-2, Cyclin-D1, Rac1, Nf-κB, HIF-1a, VEGF and MMP9 were observed. The oxidative stress markers including MDA, SOD, CAT and GPx showed insignificant changes, while the cell cycle was arrested at G2/M phase. In conclusion, BV and Mel have a synergistic anticancer effect with Sorf on HepG2 that may represent a new enhancing strategy for HCC treatment.

Mansour, G. H., M. A. El-Magd, D. H. Mahfouz, I. A. Abdelhamid, M. F. Mohamed, N. S. Ibrahim, A. H. A. A. Wahab, and E. M. Elzayat, "Bee venom and its active component Melittin synergistically potentiate the anticancer effect of Sorafenib against HepG2 cells", Bioorganic Chemistry, vol. 116: Academic Press, pp. 105329, 2021. Abstract
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Mansour, G. H., M. A. El-Magd, D. H. Mahfouz, I. A. Abdelhamid, M. F. Mohamed, N. S. Ibrahim, A. H. A. A. Wahab, and E. M. Elzayat, "Bee venom and its active component Melittin synergistically potentiate the anticancer effect of Sorafenib against HepG2 cells", Bioorganic Chemistry, vol. 116: Academic Press, pp. 105329, 2021. Abstract
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Aziz, M. M., I. K. Eyada, M. A. Abd El Megeid, and A. OM, "Bedside Evaluation of Fluid Responsiveness in Shock State using Electrical Cardiometry.", Indian Journal of Public Health Research & Development, vol. 10, no. 12, 2019. Abstract
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F.A.abdelaziz, S.elsherbini, R.ibrahim, H.algebaly, and A.Behairy, "Bedside echo for hemodynamic measurements of critically ill children with septic shock in egyptian pediatric intensive care unit", 28th annual meeting of the European Society of paediatric and neonatal intensive care, Lisbon, portugal, 7 june, 2017.
Mohammed, A. I. E., A. Fahmy, R. hosny, and H. Elatroush, Bedside CXR vs chest ultrasound for detection of pneumothorax in ICU patients, , 2017.