Publications

Export 2954 results:
Sort by: Author Title Type [ Year  (Asc)]
2023
El-Kahawy, R. M., and M. S. Mabrouk, "Benthic foraminifera as bioindicators for the heavy metals in the severely polluted Hurghada Bay, Red Sea coast, Egypt", Environmental Science and Pollution Research , vol. 30, pp. 70437–70457, 2023. s11356-023-27242-4_1.pdf
El-Kahawy, R. M., and M. S. Mabrouk, "Benthic foraminifera as bioindicators for the heavy metals in the severely polluted Hurghada Bay, Red Sea coast, Egypt", Environmental Science and Pollution Research , vol. 30, pp. 70437–70457, 2023. s11356-023-27242-4_1.pdf
Moustafa, M., M. H. Mousa, M. S. Saad, T. Basha, and S. M. Elbasiouny, "Bifurcation analysis of motoneuronal excitability mechanisms under normal and ALS conditions", Frontiers in Cellular Neuroscience, vol. 17: Frontiers Media SA, pp. 1093199, 2023. Abstract
n/a
Moustafa, M., M. H. Mousa, M. S. Saad, T. Basha, and S. M. Elbasiouny, "Bifurcation analysis of motoneuronal excitability mechanisms under normal and ALS conditions.", Frontiers in cellular neuroscience, vol. 17, pp. 1093199, 2023. Abstract

INTRODUCTION: Bifurcation analysis allows the examination of steady-state, non-linear dynamics of neurons and their effects on cell firing, yet its usage in neuroscience is limited to single-compartment models of highly reduced states. This is primarily due to the difficulty in developing high-fidelity neuronal models with 3D anatomy and multiple ion channels in XPPAUT, the primary bifurcation analysis software in neuroscience.

METHODS: To facilitate bifurcation analysis of high-fidelity neuronal models under normal and disease conditions, we developed a multi-compartment model of a spinal motoneuron (MN) in XPPAUT and verified its firing accuracy against its original experimental data and against an anatomically detailed cell model that incorporates known MN non-linear firing mechanisms. We used the new model in XPPAUT to study the effects of somatic and dendritic ion channels on the MN bifurcation diagram under normal conditions and after amyotrophic lateral sclerosis (ALS) cellular changes.

RESULTS: Our results show that somatic small-conductance Ca-activated K (SK) channels and dendritic L-type Ca channels have the strongest effects on the bifurcation diagram of MNs under normal conditions. Specifically, somatic SK channels extend the limit cycles and generate a subcritical Hopf bifurcation node in the V-I bifurcation diagram of the MN to replace a supercritical node Hopf node, whereas L-type Ca channels shift the limit cycles to negative currents. In ALS, our results show that dendritic enlargement has opposing effects on MN excitability, has a greater overall impact than somatic enlargement, and dendritic overbranching offsets the dendritic enlargement hyperexcitability effects.

DISCUSSION: Together, the new multi-compartment model developed in XPPAUT facilitates studying neuronal excitability in health and disease using bifurcation analysis.

Moustafa, M., M. H. Mousa, M. S. Saad, T. Basha, and S. M. Elbasiouny, "Bifurcation analysis of motoneuronal excitability mechanisms under normal and ALS conditions.", Frontiers in cellular neuroscience, vol. 17, pp. 1093199, 2023. Abstract

INTRODUCTION: Bifurcation analysis allows the examination of steady-state, non-linear dynamics of neurons and their effects on cell firing, yet its usage in neuroscience is limited to single-compartment models of highly reduced states. This is primarily due to the difficulty in developing high-fidelity neuronal models with 3D anatomy and multiple ion channels in XPPAUT, the primary bifurcation analysis software in neuroscience.

METHODS: To facilitate bifurcation analysis of high-fidelity neuronal models under normal and disease conditions, we developed a multi-compartment model of a spinal motoneuron (MN) in XPPAUT and verified its firing accuracy against its original experimental data and against an anatomically detailed cell model that incorporates known MN non-linear firing mechanisms. We used the new model in XPPAUT to study the effects of somatic and dendritic ion channels on the MN bifurcation diagram under normal conditions and after amyotrophic lateral sclerosis (ALS) cellular changes.

RESULTS: Our results show that somatic small-conductance Ca-activated K (SK) channels and dendritic L-type Ca channels have the strongest effects on the bifurcation diagram of MNs under normal conditions. Specifically, somatic SK channels extend the limit cycles and generate a subcritical Hopf bifurcation node in the V-I bifurcation diagram of the MN to replace a supercritical node Hopf node, whereas L-type Ca channels shift the limit cycles to negative currents. In ALS, our results show that dendritic enlargement has opposing effects on MN excitability, has a greater overall impact than somatic enlargement, and dendritic overbranching offsets the dendritic enlargement hyperexcitability effects.

DISCUSSION: Together, the new multi-compartment model developed in XPPAUT facilitates studying neuronal excitability in health and disease using bifurcation analysis.

Abdel-Aziz, A. B., K. A. Alrefaey, R. M. El-taweel, H. Sh, K. Pal, I. S. Fahim, L. A. Said, and A. G. Radwan, "Bio-inspired adsorption sheets from waste material for anionic methyl orange dye removal", SN Applied Sciences, vol. 5, issue 12: Springer International Publishing Cham, pp. 371, 2023. Abstract
n/a
El-Kahawy, R. M., N. Aboul-Ela, A. N. El-Barkooky, and W. G. Kassab, "Bio-sequence stratigraphy of the Neogene: an example from El-Wastani gas field, onshore Nile Delta, Egypt", Journal of Micropalaeontology, vol. 42, issue 2, pp. 147-169, 2023. jm-42-147-2023.pdf
Altemimia, A. B., M. J. Mohammedb, Z. T. Alkanana, S. H. Abdulrahman, S. A. Allaithad, T. G. Abedelmaksoude, Q. H. ALKaisyf, M. A. A. Najmg, F. Cacciolah, and V. P. Srinivasani, "Bioactive compounds of Citrullus colocynthis aerial parts: characterization and biological properties", Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology, 2023.
Eloutify, Y. T., R. A. El-Shiekh, K. M. Ibrahim, A. R. Hamed, A. A. Al-karmalawy, A. A. Shokry, Y. H. Ahmed, B. Avula, K. Katragunta, and I. A. Khan, "Bioactive fraction from Plumeria obtusa L. attenuates LPS-induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF-MS and molecular docking", Inflammopharmacology, vol. 31, issue 2: Springer International Publishing Cham, pp. 859-875, 2023. Abstract
n/a
Yousra T. Eloutify, Riham A. El-Shiekh, K. M. I. A. H. A. A. - K. R. A., and B. A. K. K. I. K. M. M. A. & R. Aya A. Shokry, Yasmine H. Ahmed, "Bioactive fraction from Plumeria obtusa L. attenuates LPS-induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF-MS and molecular docking", Inflammopharmacology, vol. 31, pp. 859–875, 2023.
Eloutify, Y. T., R. A. El-Shiekh, K. M. Ibrahim, A. R. Hamed, A. A. Al-karmalawy, A. A. Shokry, Y. H. Ahmed, B. Avula, K. Katragunta, I. A. Khan, et al., "Bioactive fraction from Plumeria obtusa L. attenuates LPS-induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF-MS and molecular docking", Inflammopharmacology, vol. 31, no. 2: Springer International Publishing Cham, pp. 859–875, 2023. Abstract
n/a
Elkhashab, R. A., A. Mahran, M. M. Badr, and A. M. Abu-Seida, "Bioactivity and pH of Nano-White MTA versus NeoMTATM Plus® and MTA Angelus® as root repair materials: An in vitro study", International Arab Journal of Dentistry, vol. 14, issue 2, pp. 103-111, 2023. bioactivity_of_nano_mta.pdf
Eloutify, Y. T., R. A. El-Shiekh, K. M. Ibrahim, R. Elshimy, B. Avula, K. Katragunta, I. A. Khan, and M. R. Meselhy, "Bioassay-Guided Isolation of Antimicrobial Components and LC/QToF Profile of Plumeria obtusa: Potential for the Treatment of Antimicrobial Resistance", ACS omega, vol. 8, issue 7: ACS Publications, pp. 6476-6491, 2023. Abstract
n/a
Eloutify, Y. T., R. A. El-Shiekh, K. M. Ibrahim, R. Elshimy, B. Avula, K. Katragunta, I. A. Khan, and M. R. Meselhy, "Bioassay-guided isolation of antimicrobial components and LC/QToF profile of Plumeria obtusa: Potential for the treatment of antimicrobial resistance", ACS omega, vol. 8, no. 7: American Chemical Society, pp. 6476–6491, 2023. Abstract
n/a
AL-SHOUBKI, A. D. A. M. A., M. H. Teaima, R. abdelmonem, M. A. El-Nabarawi, and S. F. Elhabal, "BIOAVAILABILITY ENHANCEMENT STRATEGIES FOR RIVAROXABAN: A NOTEWORTHY REVIEW", International Journal of Applied Pharmaceutics, vol. 15, issue 6, pp. 33-37, 2023.
Samer, M., B. A. Mohamed, S. S. Abdeen, and K. Abdelbary, "Biobutanol and bioethanol production from agricultural wastes: A cell phone application for computing the bioconversion rates", Agricultural Engineering International: CIGR Journal, vol. 25, issue 3, pp. 268-283, 2023.
Mohamed, B. A., and M. Samer, "Biobutanol production from agricultural wastes", Valorization of Wastes for Sustainable Development, Amsterdam, Elsevier, 2023.
Azeem, M., T. - R. Sun, P. G. Soundari Arockiam Jeyasundar, R. - X. Han, H. Li, H. Abdelrahman, S. M. Shaheen, Y. - G. Zhu, and G. Li, "Biochar-derived dissolved organic matter (BDOM) and its influence on soil microbial community composition, function, and activity: A review", Critical Reviews in Environmental Science and Technology: Taylor & Francis, pp. 1-23, 2023. AbstractWebsite
n/a
EL-SHOURBAGY, N. M., S. M. Farag, M. A. M. Moustafa, L. A. Al-Shuraym, Samy Sayed, and O. H. ZYAAN, "BIOCHEMICAL AND INSECTICIDAL EFFICACY OF CLOVE AND BASIL ESSENTIAL OILS AND TWO PHOTOSENSITIZERS AND THEIR COMBINATIONS ON Aphis gossypii GLOVER (HEMIPTERA: APHIDIDAE)", Bioscience Journal, vol. 39, issue e39100, pp. 1-14, 2023. moustafa2023_8_bioscience_journal.pdf