Elrahman, N. R. A. E. A.,
Association between Long Noncoding RNA Taurine Upregulated Gene1 (TUG1) and microRNA-377 In Vitiligo,
, cairo, ( Cairo University), 2019.
AbstractBackground: Vitiligo is the commonest hypopigmented skin disorder. Taurine upregulated gene1(TUG1), one of Long noncoding RNAs (LncRNA) that plays a role in melanogenesis. microRNA-377 (miRNA-377) is a conserved non-coding RNA that regulates angiogenesis and promotes oxidative stress. Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily. PPARγ activators stimulate melanogenesis. Interleukin-17(IL17) has been implicated in the pathogenesis of several immunological diseases.
Aim: This work aimed to detect the expression levels of TUG1, miRNA-377, PPARγ and IL-17 among vitiligo subjects and to investigate their possible role in the pathogenesis of vitiligo.
Methods: This study was conducted on 30 healthy control and 30 vitiligo patients. TUG1 and miRNA-377 were detected in serum by real- time-PCR, Also PPARγ and IL-17 were assessed in tissue by Real-time PCR.
Results: TUG1and PPARγ level was significantly down regulated in vitiligo group compared to control group, on the other hand miRNA-377 and IL-17 was significantly up regulated in vitiligo group compared to control group.
Conclusion: This study demonstrated the dysregulated expressions of TUG1 and miR-377 in patients with vitiligo and suggested that both contributed to its pathogenesis and that might be through PPARγ and IL-17.
Key words: Vitiligo /TUG1/ miRNA377/ PPAR γ / IL17.
adrousy Gomaa, M. A., M. Albatrawy, A. ahmed albakry, and A. Khoweiled,
Attention and hyperactivit symptoms in offspring of bipolar pateints,,
, cairo, cairo university, 2005.
Zawbaa, H. M., and A. E. Hassanien,
Automatic Soccer Video Summarization,
, Cairo, Cairo Unversity, 2012.
Abstract This thesis presents an automatic soccer video summarization system using machine learning (ML) techniques. The proposed system is composed of ve phases. Namely; in the pre-processing phase, the system segments the whole video stream into small video shots. Then, in the shot processing
phase, it applies two types of classication (shot type classication and play / break classification) to the video shots resulted from the pre-processing phase. Afterwards, in the replay detection phase, the proposed system applies two machine learning algorithms, namely; support vector machine (SVM) and articial neural network (ANN), for emphasizing important segments with championship logo appearance. Also, in the excitement event detection phase, the proposed system uses both machine learning algorithms for detecting the scoreboard which contain an information about the score of the game. The proposed system also uses k-means algorithm and Hough line transform for detecting vertical goal posts and Gabor lter for detecting goal net. Finally, in the event detection and summarization phase, the proposed system highlights the most important events during the match. Experiments on real soccer videos demonstrate encouraging results. The event detection and summarization has attained recall 94% and precision 97.3% for soccer match videos from ve international soccer championships.