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Youssef, S. H., M. A. M. Hegazy, D. Mohamed, and A. M. Badawey, "ANALYSIS OF PARACETAMOL, PSEUDOEPHEDRINE AND BROMPHENIRAMINE IN COMTREX® TABLETS USING CHEMOMETRIC METHODS", WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, vol. 6, issue 6, pp. 1644-1659, 2017. souha_paper_world_journal_of_pharmacy_and_pharmaceutical_sciences.pdf
Youssef, D., and N. H. Solouma, "Accurate detection of blood vessels improves the detection of exudates in color fundus images", International Journal of Computer Methods and Programs in Biomedicine (CMPB), vol. 108, issue 3, pp. 1052-1061, 2012.
Youssef, S. H., D. Mohamed, M. A. M. Hegazy, and A. Badawey, "Analytical methods for the determination of paracetamol, pseudoephedrine and brompheniramine in Comtrex tablets", BMC chemistry, vol. 13, issue 78, pp. 1-15, 2019. bmc_chemistry.pdf
Youssef, G., Z. Saad, W. Ammar, and Yasser Sharaf, "Assessment of left ventricular regional wall motion abnormalities using regional time-volume curves obtained by real time three-dimensional echocardiography", The Egyptian heart journal, vol. 70, issue 3, pp. 189-194, 2018. 3d_assessment_of_swma.pdf
Youssef, S. H., M. A. M. Hegazy, D. Mohamed, and A. M. Badawey, Analysis of paracetamol, pseudo-ephedrine andbrompheniramine in comtrex tablets using chemometric methods, : World journal of pharmacy and pharmaceutical sciences, 2017. Abstract
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Youssef, S. H., D. Mohamed, M. A. M. Hegazy, and A. Badawey, "Analytical methods for the determination of paracetamol, pseudoephedrine and brompheniramine in Comtrex tablets", BMC chemistry, vol. 13, issue 1: BioMed Central, pp. 1-15, 2019. Abstract
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Youssef, D., and N. Solouma, "Accurate Detection of Blood Vessels I mproves the Detection of Exudates in Color Fundus Images", Computer methods and programs in biomedicine, vol. 108, pp. 1052–1061, 2012.
Youssef, G., "Aortic valve diseases in pregnancy", E-Journal of Cardiology Practice, vol. Vol. 18, issue N° 19, 2020. avd_during_pregnancy.pdf
Youssef, M. F., K. M. F. Elsayed, and A. H. Zahran, "Adaptive radio duty cycling in ContikiMAC: Proposal and analysis", Internet of Things (WF-IoT), 2014 IEEE World Forum on: IEEE, pp. 491–495, 2014. Abstract
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Youssef, F. S., H. A. El-Banna, H. Y. Elzorba, and A. M. Galal, "Application of some nanoparticles in the field of veterinary medicine", International Journal of Veterinary Science and Medicine, vol. VOL. 7, issue NO. 1, pp. 78–93, 2019.
Youssef, S. H., M. A. ‑M. Hegazy, D. Mohamed, and A. M. Badawey, Analysis of paracetamol, pseudoephedrine and cetirizine in Allercet Cold, , 2018. Abstract
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Youssef, O., H. Anwar, A. G. Mohamed, O. Mansour, I. Gouda, and W. Hamimy, "Axillary Lymph Nodes Retrieval Is Not Affected After Neoadjuvant Chemotherapy for Locally Advanced Breast Cancer", ANNALS OF SURGICAL ONCOLOGY, vol. 17, no. 2: SPRINGER 233 SPRING ST, NEW YORK, NY 10013 USA, pp. S193–S193, 2010. Abstract
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Youssef, R. M., M. A. Saleh, M. M. Korany, Z. A. Nour, and M. El-Kalioby, "Assessment of tissue E-cadherin and its proteolytic serum fragment in pemphigus vulgaris before and after remission: A case-control study.", Journal of cosmetic dermatology, 2022. Abstract

BACKGROUND: E-cadherin is a classic cadherin that mediates keratinocyte adhesion.

AIMS: To assess the tissue expression of E-cadherin and its proteolytic serum fragment (soluble E-cadherin) in pemphigus vulgaris (PV) before and after clinical remission compared with controls.

PATIENTS: Thirty-seven PV patients and thirty controls were enrolled. Pemphigus disease area index (PDAI) was calculated for patients at baseline and after remission. Punch biopsy specimens were taken from patients before, and after remission, and from controls for assessment of tissue E-cadherin by immunofluorescence. Similarly, serum samples were collected for assessment of serum soluble E-cadherin by ELISA.

RESULTS: Presence, intensity, and mean intensity of tissue E-cadherin were significantly reduced in PV patients before treatment compared with controls (p < 0.001). Detected E-cadherin showed mainly a basal and suprabasal distribution with cell surface and a cytoplasmic expression. Serum E-cadherin was significantly higher in patients before treatment compared with controls (p = 0.006). With remission, tissue E-cadherin presence, intensity, mean intensity, and serum E-cadherin showed statistically significant improvement (p = 0.003, <0.001, <0.001, and 0.003 respectively). Tissue E-cadherin presence and serum E-cadherin level reached values equivalent to the controls (p = 0.49 and 0.44, respectively).

CONCLUSIONS: Disruption of tissue E-cadherin and upregulation of serum soluble E-cadherin can contribute to the pathogenesis of PV. Clinical remission of PV is associated with normalization of tissue and serum E-cadherin.

Youssef, G., W. Ammar, Z. Saad, and Yasser Sharaf, "Assessment of left ventricular regional wall motion abnormalities using regional time-volume curves obtained by real time three-dimensional echocardiography", The Egyptian Heart Journal, vol. 70, issue 70, pp. 189-194, 2018.
Youssef, S. H., M. A. B. D. E. L. - M. Hegazy, D. Mohamed, and A. M. Badawey, "Analysis of paracetamol, pseudoephedrine and cetirizine in Allercet Cold® capsules using spectrophotometric techniques", Chemistry Central Journal, vol. 12, issue 1: BioMed Central, pp. 1-14, 2018. Abstract
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Yousry, S. M., Y. Sedky, and A. Sobieh, "Association of IL-4 (intron 3) and IL-10 (-1082) gene polymorphisms with risk of mitral valve disease in children with rheumatic heart disease", Cardiology in the Young, vol. 26, issue 7: Cambridge University Press, pp. 1290, 2016. Abstract
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Yousry, S. M., Y. Sedky, and A. Sobieh, "Association of IL-4 (intron 3) and IL-10 (-1082) gene polymorphisms with risk of mitral valve disease in children with rheumatic heart disease", Cardiology in the young: Cambridge Univ Press, pp. 1–7, 2015. Abstract
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Yousry, M., A. Kamel, and O. Hegazi, "Aligning Organization Measurements with Organization Strategic Goals", The Egyptian Computer Journa, vol. 37, issue 2, 2009.
Yousry, S. M., Y. Sedky, and A. Sobieh, "Association of IL-4 (intron 3) and IL-10 (-1082) gene polymorphisms with risk of mitral valve disease in children with rheumatic heart disease", Cardiology in the Young, vol. 26, issue 7: Cambridge University Press, pp. 1290-1296, 2016. Abstract
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Yousry, S. M., Y. Sedky, and A. Sobieh, "Association of IL-4 (intron 3) and IL-10 (-1082) gene polymorphisms with risk of mitral valve disease in children with rheumatic heart disease.", Cardiology in the young, pp. 1-7, 2015 Oct 28. Abstract

Aim Rheumatic heart disease is an inflammatory disease of cardiac tissue. The underlying pathogenic mechanisms highlight a complex interplay of immunological, genetic, and environmental factors. The aim of the present study was to investigate whether IL-4 (intron 3) and IL-10 (-1082) gene polymorphisms could be associated with susceptibility and/or severity of rheumatic heart disease among patients from the Egyptian population. Materials and methods A cohort of 140 Egyptian children with rheumatic heart disease and 100 healthy controls were enrolled in this case-control study. Genotyping for IL-4 (intron 3) and IL-10 (-1082) gene polymorphisms was carried out for all patients using a polymerase chain reaction-based analysis.

RESULTS: No significant difference in the distribution of genotypes and allelic frequencies between rheumatic heart disease cases and controls for IL-4 (intron 3) (p=0.17; OR 1.07, 95% CI 0.82-3.74) and IL-10 (-1082) (p=0.49; OR 1.03, 95% CI 0.65-2.71) gene polymorphisms was observed. Further categorisation of patients into mitral valve disease and combined valve disease subgroups showed that cases with mitral valve disease have significantly higher frequency of the RP2 allele of IL-4 (intron 3) (p=0.03; OR 2.98, 95% CI 1.93-6.15) and the G allele of IL-10 (-1082) (p=0.04; OR 2.14, 95% CI 1.62-4.95) when compared with controls. Discussion Our study shows that IL-4 (intron 3) and IL-10 (-1082) gene polymorphisms are not significantly associated with susceptibility to rheumatic heart disease, but they might play a role in the pathogenesis of patients with mitral valve disease.

Yousef, H. A., E. A. Abdelfattah, and M. Augustyniak, "Antioxidant enzyme activity in responses to environmentally induced oxidative stress in the 5th instar nymphs of Aiolopus thalassinus (Orthoptera: Acrididae)", Environmental Science and Pollution Research, vol. 26, no. 4: Springer Berlin Heidelberg, pp. 3823–3833, 2019. Abstract
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Yousef, A. A., F. Y. Mohamed, N. F. Boraey, N. E. Akeel, A. A. Soliman, N. M. Waked, M. I. A. Hashem, H. Shehata, D. S. Fahmy, and A. Ismael, "Association of Plasminogen Activator Inhibitor 1 (PAI-1) 4G/5G Polymorphism and Susceptibility to SLE in Egyptian Children and Adolescents: A Multicenter Study [Corrigendum]", Journal of Inflammation Research, vol. 14: Dove Press, pp. 265-266, 2021. Abstract
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Yousef, H. A., E. A. Abdelfattah, and M. Augustyniak, "Antioxidant enzyme activity in responses to environmentally induced oxidative stress in the 5th instar nymphs of Aiolopus thalassinus (Orthoptera: Acrididae)", Environmental Science and Pollution Research, vol. 26, no. 4: Springer Berlin Heidelberg, pp. 3823–3833, 2019. Abstract
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Yousef, H. A., E. A. Abdelfattah, and M. Augustyniak, "Antioxidant enzyme activity in responses to environmentally induced oxidative stress in the 5th instar nymphs of Aiolopus thalassinus (Orthoptera: Acrididae)", Environmental Science and Pollution Research, vol. 26, issue 4, pp. 3823–3833, 2019.
Yousef, H. A., E. A. Abdelfattah, and M. Augustyniak, "Antioxidant enzyme activity in responses to environmentally induced oxidative stress in the 5th instar nymphs of Aiolopus thalassinus (Orthoptera: Acrididae)", Environmental Science and Pollution Research, vol. 26, no. 4: Springer Berlin Heidelberg, pp. 3823–3833, 2019. Abstract
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